CopciAB_250393
Coprinopsis cinerea A43mutB43mut pab1-1 #326

General data

Systematic name CopciAB_250393 Strain Coprinopsis cinerea Okayama 7
Standard name CBK1 Synonyms 250393
Uniprot id Functional description Extension to Ser/Thr-type protein kinases
Location scaffold_6:1695617..1697838 Strand +
Gene length (nt) 2222 Transcript length (nt) 1705
CDS length (nt) 1461 Protein length (aa) 486

Reciprocal best hits in model fungi

Strain name Gene / Protein name

Orthologs in mushroom models

Strain name Gene / Protein name Pident E-value Bits
Hypsizygus marmoreus strain 51987-8 Hypma_RDB20909 86.3 5.353E-288 878
Pleurotus eryngii ATCC 90797 Pleery1_1445279 88.3 6.123E-276 843
Pleurotus ostreatus PC15 PleosPC15_2_1065976 88.3 5.206E-276 843
Pleurotus ostreatus PC9 PleosPC9_1_88355 88.3 5.096E-276 843
Agaricus bisporus var bisporus (H97) Agabi_varbisH97_2_185974 88.4 4.922E-275 840
Agaricus bisporus var. burnettii JB137-S8 Agabi_varbur_1_118835 88.4 5.129E-275 840
Lentinula edodes B17 Lened_B_1_1_3063 83.8 3.108E-272 832
Lentinula edodes NBRC 111202 Lenedo1_1125643 83.8 3.928E-272 832
Lentinula edodes W1-26 v1.0 Lentinedodes1_21982 83.6 8.655E-272 831
Schizophyllum commune H4-8 Schco3_2619461 86.5 9.898E-272 831
Flammulina velutipes Flave_chr06AA00879 84.9 2.141E-269 824

Expression

Name Summary Attribution Assay type
Carbon metabolism Transcriptional changes along alternative morphogenetic paths of C. cinerea Xie et al. 2020 RNA-Seq
Sample Mean cpm SD cpm Se of mean
sclerotia 111.6876 8.8789 5.1262
oidia 122.7506 13.1027 7.5648
vegetative_mycelium 101.3878 8.1617 4.7121
primordia 95.1803 2.4934 1.4396
hyphal_knot 120.4266 5.407 3.1217
young_fruiting_body 80.9154 13.8332 7.9866
Complex carbon sources 1 (long incubation) Expression profiling on diverse complex carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Control - glucose 109.8383 7.1987 4.1562
Wheat bran 135.9699 24.3914 14.0824
Horse manure 134.8312 25.1677 14.5306
Oak leaves 91.8284 23.286 13.4442
Hay 113.9374 24.1317 13.9324
Corn stalk 101.5482 18.8622 10.8901
Pectine 104.8418 4.0192 2.3205
Microcrystalline cellulose 122.1431 4.3453 2.5087
Xylose 113.5246 8.7985 5.0798
Cellobiose 129.6372 10.8089 6.2405
Lignin 90.4056 7.4903 4.3245
Apple peels 146.7125 8.9789 5.184
Coprinopsis challenged with bacteria Transcriptional response to Bacillus subtilis and Escherichia coli. Kombrink et al. 2018 RNA-Seq
Sample Mean cpm SD cpm Se of mean
Control 177.3226 10.4356 6.025
Bsubtilis 144.9703 2.5658 1.4814
Ecoli 93.6089 4.9692 2.869
Early development 1 Time series expression profiling of basidiospore and oidium germination Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
BS 0h 19.8289 3.2734 1.8899
BS 4h 28.0881 7.3267 4.2301
BS 8h 26.393 4.0456 2.3357
BS 12h 46.2199 7.9698 4.6014
Oidia 0 h 27.8638 2.1011 1.2131
Oidia 18 h 35.2624 4.2947 2.4795
Sclerotia 62.5253 4.4201 2.552
Early development 2 Time series expression profiling of mycelial growth, light induction and fruiting body initiation. Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
DM 12h 62.4625 0.4388 0.2533
DM 36h 59.0005 2.6174 1.5112
DM 60h 71.2939 13.8398 7.9904
DM 84h 83.1562 4.4972 2.5965
DM 108h 64.1633 2.3232 1.3413
DM 132h 64.1181 8.0828 4.6666
DM 156hAE 93.4468 16.912 9.7642
ELI1hAE 65.8333 5.4355 3.1382
ELI2hAE 69.1364 1.6119 0.9306
LI2hAE 66.4461 7.4941 4.3267
LI6hAE 84.5357 11.0387 6.3732
LI12hAE 70.4211 8.5299 4.9247
LI18hAE 63.993 3.6502 2.1074
LI 24hAE 60.7519 2.8474 1.6439
DM 156hAM 63.9546 13.6342 7.8717
ELI1hAM 46.7635 9.91 5.7215
ELI2hAM 57.9137 12.6431 7.2995
LI2hAM 61.0897 5.3373 3.0815
LI6hAM 72.5229 4.3629 2.5189
LI12hAM 54.5748 9.7251 5.6148
LI18hAM 55.8124 5.0477 2.9143
LI 24hAM 62.7505 15.6957 9.0619
LI 24hHK 43.4769 10.7125 6.1849
L/D 6h 73.5604 8.4907 4.9021
L/D 12h 67.6593 10.0999 5.8312
L/D 18h 75.6322 7.8181 4.5138
L/D 24h 64.2464 9.0576 5.2294
Fruiting body development RNA-Seq analysis of fruiting body development Krizsan et al. 2019 RNA-Seq
Sample Mean cpm SD cpm Se of mean
Vegetative mycelium 78.0684 9.1224 5.2668
Hyphal knots 84.8466 6.7442 3.8938
Primordium 1 89.6408 9.8745 5.7011
Primordium 2 90.0925 10.0125 5.7807
Young Fruiting body cap 94.5169 7.3288 4.2313
Younf fruiting body gill 93.2394 4.3968 2.5385
Young fruiting body stipe 84.4518 4.5812 2.645
Mature fruiting body cap_gill 111.7096 21.6356 12.4913
Mature fruiting body stipe 134.546 10.9005 6.2934
Nitrogen sources (12h incubation) Expression profiling on diverse nitrogen sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Complete medium - control 97.1454 14.3743 8.299
NH4NO3 102.9892 16.7166 9.6513
Proline 77.6376 5.9622 3.4423
Tryptophan 96.6752 24.6172 14.2127
Isoleucin 82.8613 4.7841 2.7621
Arginine 82.1607 4.1587 2.401
Metionine 70.728 1.5976 0.9224
NaNO3 74.5404 2.2841 1.3187
Plant biomass (12h incubation) Expression profiling on diverse plant biomasses as carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose - control 97.1454 14.3743 8.299
Citrus peel 54.3067 2.486 1.4353
Poplar leaves 96.3161 9.388 5.4202
Typha leaves 84.9215 12.9033 7.4497
Overwintered Salix leaves 89.7605 15.6873 9.0571
Reed flowering 73.0383 18.8549 10.8859
Tigernut 81.6868 0.9226 0.5326
Energy cane 90.7507 16.5722 9.568
Guar gum 109.0791 41.8766 24.1775
Apple peels 109.2955 15.3174 8.8435
Cellobiose 91.4685 5.1228 2.9576
Corn stalk 113.9765 3.9276 2.2676
Horse manure 110.4951 2.369 1.3677
Lignin 66.8025 20.4529 11.8085
Microcrystalline cellulose 87.314 13.965 8.0627
Oak leaves 113.3577 12.8747 7.4332
Pectin esterified 99.8917 20.0851 11.5962
Poplar sawdust 126.6937 26.2122 15.1336
Wheat bran 126.4398 17.0883 9.866
Chlamydomonas reinhardtii 107.8922 6.6411 3.8342
Vertatryl alcohol 50.5317 2.9271 1.6899
Furfural 57.928 4.5531 2.6287
Autoclaved mycelium 84.7306 11.0285 6.3673
Simple and complex carbon and nitrogen sources Expression profiling on diverse complex carbon and nitrogen sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose control 182.126 4.4803 2.5867
Ribose 165.7785 14.2233 8.2118
Mannose 185.067 17.0398 12.049
Fructose 181.4404 27.4594 15.8537
Arabinose 175.745 10.2164 5.8985
Xylose 176.2344 12.7259 7.3473
Galacturonic acid 166.7778 7.0734 4.0839
Rhamnogalacturonan 168.2896 8.3105 4.7981
Pectin esterified 160.5503 4.3031 2.4844
Polygalacturonic acid 170.517 7.5613 4.3655
Sodium acetate 170.4507 11.3598 6.5586
No nitrogen 146.0879 6.5978 3.8092
BSA 160.3558 5.8 3.3487
Glutamine 149.8827 3.5847 2.0696
No phosphate 129.846 8.8096 5.0862
No carbon 164.9323 10.5784 7.4801
No sulphur 157.2005 15.9825 9.2275
Simple and complex carbon sources (12h incubation) Expression profiling on diverse complex carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose - control 97.1454 14.3743 8.299
Amylose 151.6448 6.4364 3.716
Fucose 128.3031 14.2214 8.2107
Galactose 131.4047 15.1543 8.7493
Lactose 105.1316 6.3752 3.6807
Maltose 117.6973 10.6373 6.1415
Mannitol 109.2219 2.8159 1.6258
Rhamnose 105.8736 14.4191 8.3248
Sorbitol 132.4602 6.916 3.993
Trehalose 109.4313 19.4701 11.241
Glycerol 107.2605 28.1386 16.2458
Glucuronic acid 145.9069 8.343 4.8168
Arabinan 118.4892 29.5655 17.0697
Galactan 93.8501 9.2177 5.3218
Galactomannan 133.1449 68.1168 39.3273
Glucan 96.7205 30.3899 17.5456
Xylan 133.5541 3.7846 2.1851
Xyloglucan 134.4545 10.4918 6.0574
Arabinogalactan 147.0799 13.8585 8.0012
Pectin 95.1769 22.1218 12.772
Rhamnogalacturonan 70.107 7.1635 4.1359
Polygalacturonic acid 112.2837 18.1872 10.5004
Mannan 116.0884 16.1655 9.3332
Amylopectin 97.8818 28.7249 16.5843
Inulin 111.6011 11.3946 6.5787
BSA 55.4557 6.0608 3.4992
Starvation induced by water agar transfer Expression profiling on starvation induced by transfer to water agar Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Control 71.2939 13.8398 7.9904
2h WAT 75.8718 9.8409 5.6816
4h WAT 68.1947 7.8909 4.5558
8h WAT 67.9275 7.5205 4.342
16h WAT 64.3788 6.9692 4.0237
24h WAT 66.2106 3.6648 2.1159
WAT hyphal knot -30h 56.7524 6.501 3.7533
WAT hyphal knot -22h 73.0812 3.6286 2.095
WAT hyphal knot -15h 73.9915 6.3451 3.6634
WAT hyphal knot -7.5h 70.2881 5.595 3.2303
WAT hyphal knot 64.5095 10.8023 6.2367
WAT hyphal knot +7.5h 79.3201 5.1292 2.9614
Straw time series Time series expression profiling on straw as a carbon source Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose control 81.3979 3.0094 1.7375
Straw 3h 61.7441 3.5388 2.0431
Straw 6h 62.3618 14.6772 8.4739
Straw 12h 72.22 3.3323 1.9239
Straw 24h 80.9402 8.6185 4.9759
Stress conditions 1 Expression profiling under various stress conditions Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Flask control 37.2651 9.2299 5.3289
Frost (-20C, 30min) 37.7603 2.7055 1.562
Heat shock (47C, 2h) 30.229 4.3256 2.4974
High CO2 48.2479 10.4101 6.0103
Drought (4% agar, 12h) 51.3719 16.5459 9.5528
Oxidative (1mM H2O2, 3h) 26.08 1.7769 1.0259
Acidic (pH4, 3h) 36.1987 7.9951 4.6159
Alkaline (pH9, 3h) 41.2531 2.3555 1.36
Osmotic (sorbitol 2h) 42.1664 5.1815 2.9915
CongoRed (3h) 28.1512 5.0046 2.8894
Cobalt chloride control 36.1815 2.3049 1.3307
Cobalt chloride 2mM 34.4397 4.0347 2.3294
Stress conditions 2 Expression profiling under various stress conditions Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Flask control 51.5153 28.3257 16.3538
Cold stimulation 52.2898 11.8386 6.835
Scratched surface 39.0653 7.7107 4.4517
Ca2+, 200mM, 24h 28.3365 1.6194 0.9349
Cu2+, 2mM, 6h 41.7932 14.016 8.0921
Voriconazole 48.9276 2.6428 1.5258
Trichoderma interaction, early 53.1707 7.2351 4.1772
Trichoderma interaction 60h 22.4366 8.9764 5.1826
Cobalt chloride 2mM repeat 52.1385 10.7451 6.2037
Hypoxia 52.3964 6.195 3.5767
Hypoxia control 63.7103 9.8294 5.675
Protoplastation control 44.5509 0.6192 0.4378
Protoplastation 3.5h 39.6386 8.9019 6.2946
Protoplastation 1.5h 41.4632 2.2493 1.5905

General data

Systematic name CBK1
Protein id CopciAB_250393.T0
Description Extension to Ser/Thr-type protein kinases

Annotation summary

0 100 200 300 400 486

Conserved domains

Analysis Signature accession Signature description InterPro Accession Start End
Pfam PF00069 Protein kinase domain IPR000719 117 416

SignalP

Prediction Start End Score
No records

Transmembrane domains

Domain n Start End Length
No records

InterPro

Accession Description
IPR000719 Protein kinase domain
IPR008271 Serine/threonine-protein kinase, active site
IPR017441 Protein kinase, ATP binding site
IPR000961 AGC-kinase, C-terminal
IPR011009 Protein kinase-like domain superfamily

GO

Go id Term Ontology
GO:0004672 protein kinase activity MF
GO:0005524 ATP binding MF
GO:0006468 protein phosphorylation BP
GO:0004674 protein serine/threonine kinase activity MF

KEGG

KEGG Orthology
K08286

EggNOG

COG category Description
T Extension to Ser/Thr-type protein kinases

CAZy

Class Family Subfamily
No records

Transcription factor

Group
No records

Conservation of CopciAB_250393 across fungi.

Arrow shows the origin of gene family containing CopciAB_250393.

Protein

Sequence id CopciAB_250393.T0
Sequence >CopciAB_250393.T0
MHQHLATAGPSKSPMNSQGDRTGTIQRPDDYVYFERSTAKFSSDAVARATAAKLKLESYYKMAVDSAIERNARRI
EMETRLTQLHTQDAKDREIRKYSKTESQHLRLRRTKIKLSDFKTVKVIGKGAFGEVRLVQKVDTGKVYAMKSLQK
AEMLKRDQLAHVRAERDVLAESTSPWVVQLFYSFQDPLYLYLIMEFLPGGDLMTMLMKYDVFSEDVTRFYMAECI
LAIEAVHNLGYIHRDIKPDNVLIDRNGHLKLSDFGLSTGLHKATDGEIYKRYLEQEKTKDNSRNSVQVNPINLTM
SREQIATWKANRRKLAYSTVGTPDYIAPEVFMMKGYGKECDWWSLGAIFFECLVGYAPFCSDNPGDTYKKIIDWP
RYLIFPEEVYISKEGEDLIRGMMNWADKRLTVEQIKNHPWFFGADWNSLRYIEPPFVPRLSSITDTSYFPTDDLG
NVSNQLDQVESVSAEKDLAFLGFTFKRFTGGPGASG
Length 486

Coding

Sequence id CopciAB_250393.T0
Sequence >CopciAB_250393.T0
ATGCACCAACACCTGGCGACTGCTGGCCCATCCAAATCACCCATGAACAGCCAAGGAGATCGCACTGGAACCATC
CAAAGACCAGACGACTATGTCTACTTTGAACGGTCGACAGCCAAGTTCAGCTCAGATGCCGTGGCGCGTGCAACG
GCTGCAAAGCTGAAGCTTGAGTCGTACTACAAGATGGCAGTCGACTCTGCTATTGAAAGAAATGCAAGGCGAATC
GAGATGGAGACGAGACTCACGCAATTGCATACTCAAGATGCGAAGGATAGAGAAATTCGAAAATACTCCAAGACT
GAGTCGCAGCATCTGAGGCTCAGGAGAACGAAGATCAAGCTGTCAGACTTCAAGACTGTCAAGGTCATCGGGAAG
GGTGCCTTTGGTGAGGTACGCCTGGTCCAGAAAGTCGACACCGGAAAGGTCTACGCAATGAAGAGCTTGCAGAAG
GCCGAGATGTTAAAGCGGGATCAGTTGGCCCACGTGCGGGCAGAACGCGATGTTCTGGCAGAGTCCACCTCACCA
TGGGTCGTTCAGCTCTTCTACTCCTTCCAAGACCCGCTATACCTCTATCTCATCATGGAGTTCCTTCCTGGAGGC
GATCTAATGACCATGTTGATGAAATACGACGTGTTCTCGGAAGACGTCACCCGATTCTACATGGCTGAATGTATC
CTGGCGATCGAAGCGGTCCACAACTTGGGGTACATTCATCGGGACATCAAGCCGGACAATGTGTTGATTGACCGG
AATGGTCACTTGAAGTTGTCGGATTTCGGTCTCTCCACTGGACTCCACAAGGCCACCGACGGAGAAATCTACAAA
CGGTATCTGGAACAAGAGAAGACCAAGGACAATTCGCGGAACAGTGTTCAAGTCAACCCCATTAACCTTACCATG
AGCCGTGAACAGATCGCGACCTGGAAGGCTAATCGACGGAAGTTGGCGTATTCGACGGTCGGAACTCCCGACTAT
ATTGCTCCGGAAGTGTTCATGATGAAGGGCTACGGAAAGGAGTGCGACTGGTGGTCACTGGGTGCCATTTTCTTC
GAATGCTTGGTTGGCTATGCGCCCTTCTGCTCGGACAACCCGGGGGATACGTACAAGAAGATCATCGACTGGCCA
CGTTACCTCATCTTCCCAGAAGAGGTATACATCTCCAAGGAGGGGGAGGACCTTATTAGAGGCATGATGAATTGG
GCAGACAAGCGACTGACTGTGGAACAGATCAAGAACCACCCCTGGTTCTTCGGCGCCGATTGGAACTCCCTCCGC
TACATCGAACCACCATTTGTTCCCCGTCTTAGCTCGATAACGGATACCTCATATTTCCCTACCGACGATCTTGGC
AATGTGTCCAACCAGTTGGACCAAGTGGAGAGCGTCAGTGCGGAGAAGGACCTTGCTTTCCTCGGATTCACATTC
AAACGGTTTACGGGTGGGCCTGGAGCCTCTGGTTAA
Length 1461

Transcript

Sequence id CopciAB_250393.T0
Sequence >CopciAB_250393.T0
AACCTCGTAGCACAACGCCAACCGACAGTCGGCAACCGTCGCTACCTGACAGCAAAGCTAGATTCTCGTGGCCAT
CGTTCGCGACGACCACCGACGGCCGCTTTAGTTCCCGACTTCCTTCAAAGCCCCAACCGAATCAGTAACTCTTGT
CTATGCACCAACACCTGGCGACTGCTGGCCCATCCAAATCACCCATGAACAGCCAAGGAGATCGCACTGGAACCA
TCCAAAGACCAGACGACTATGTCTACTTTGAACGGTCGACAGCCAAGTTCAGCTCAGATGCCGTGGCGCGTGCAA
CGGCTGCAAAGCTGAAGCTTGAGTCGTACTACAAGATGGCAGTCGACTCTGCTATTGAAAGAAATGCAAGGCGAA
TCGAGATGGAGACGAGACTCACGCAATTGCATACTCAAGATGCGAAGGATAGAGAAATTCGAAAATACTCCAAGA
CTGAGTCGCAGCATCTGAGGCTCAGGAGAACGAAGATCAAGCTGTCAGACTTCAAGACTGTCAAGGTCATCGGGA
AGGGTGCCTTTGGTGAGGTACGCCTGGTCCAGAAAGTCGACACCGGAAAGGTCTACGCAATGAAGAGCTTGCAGA
AGGCCGAGATGTTAAAGCGGGATCAGTTGGCCCACGTGCGGGCAGAACGCGATGTTCTGGCAGAGTCCACCTCAC
CATGGGTCGTTCAGCTCTTCTACTCCTTCCAAGACCCGCTATACCTCTATCTCATCATGGAGTTCCTTCCTGGAG
GCGATCTAATGACCATGTTGATGAAATACGACGTGTTCTCGGAAGACGTCACCCGATTCTACATGGCTGAATGTA
TCCTGGCGATCGAAGCGGTCCACAACTTGGGGTACATTCATCGGGACATCAAGCCGGACAATGTGTTGATTGACC
GGAATGGTCACTTGAAGTTGTCGGATTTCGGTCTCTCCACTGGACTCCACAAGGCCACCGACGGAGAAATCTACA
AACGGTATCTGGAACAAGAGAAGACCAAGGACAATTCGCGGAACAGTGTTCAAGTCAACCCCATTAACCTTACCA
TGAGCCGTGAACAGATCGCGACCTGGAAGGCTAATCGACGGAAGTTGGCGTATTCGACGGTCGGAACTCCCGACT
ATATTGCTCCGGAAGTGTTCATGATGAAGGGCTACGGAAAGGAGTGCGACTGGTGGTCACTGGGTGCCATTTTCT
TCGAATGCTTGGTTGGCTATGCGCCCTTCTGCTCGGACAACCCGGGGGATACGTACAAGAAGATCATCGACTGGC
CACGTTACCTCATCTTCCCAGAAGAGGTATACATCTCCAAGGAGGGGGAGGACCTTATTAGAGGCATGATGAATT
GGGCAGACAAGCGACTGACTGTGGAACAGATCAAGAACCACCCCTGGTTCTTCGGCGCCGATTGGAACTCCCTCC
GCTACATCGAACCACCATTTGTTCCCCGTCTTAGCTCGATAACGGATACCTCATATTTCCCTACCGACGATCTTG
GCAATGTGTCCAACCAGTTGGACCAAGTGGAGAGCGTCAGTGCGGAGAAGGACCTTGCTTTCCTCGGATTCACAT
TCAAACGGTTTACGGGTGGGCCTGGAGCCTCTGGTTAAGGGAGGTTCTGAAGCTGGAACCATCGCCTTTTGTATA
TTTTTTAAAAGCGTGGAAACGTCATATTTCATCTCAATGCAAAGTTGTAAAGTCT
Length 1705

Gene

Sequence id CopciAB_250393.T0
Sequence >CopciAB_250393.T0
AACCTCGTAGCACAACGCCAACCGACAGTCGGCAACCGTCGCTACCTGACAGCAAAGCTAGATTCTCGTGGCCAT
CGTTCGCGACGACCACCGACGGCCGCTTTAGTTCCCGACTTCCTTCAAAGCCCCAACCGAATCAGTAACTCTTGT
CTATGCACCAACACCTGGCGACTGCTGGCCCATCCAAATCACCCATGAACAGCCAAGGAGATCGCACTGGAACCA
TCCAAAGACCAGACGACTGTAAGCCAGCTTCTCCGTGCTAGTAACAACTGCCACCAACGTGTCTCCATCGGTAGA
TGTCTACTTTGAACGGTCGACAGCCAAGTTCAGCTCAGATGCCGTGGCGCGTGCAACGGCTGCAAAGCTGAAGCT
TGAGTCGTACTACAAGATGGCAGTCGACTCTGCTATTGAAAGAAATGCAAGGTCAGCAATCCGCAACTACGACGA
TGCGAACGATCGAGCAACAGAGATGTCCTGACATGATATACCGCTCCACGTACCACCAGGCGAATCGAGATGGAG
ACGAGACTCACGCAATTGCATACTCAAGATGCGAAGGATAGAGAAATTCGAAAATACTCCAAGACTGAGTCGCAG
CATCTGAGGCTCAGGAGAACGAAGATCAAGCTGTCAGACTTCAAGACTGTCAAGGTCATCGGGAAGGGTGCCTTT
GGTGAGGTATAGCTTCTGGTGTTTGGAACTCGGGGTCATGTCCCTGATTGTTCGCTATTAGGTACGCCTGGTCCA
GAAAGTCGACACCGGAAAGGTCTACGCAATGAAGAGCTTGCAGAAGGCCGAGATGTTAAAGCGGGATCAGGTATG
TGTCGCCCATCTAATACCCCACACCATACGCTGAACCTATTCGTAGTTGGCCCACGTGCGGGCAGAACGCGATGT
TCTGGCAGAGTCCACCTCACCATGGGTCGTTCAGCTCTTCTACTCCTTCCAAGACCCGCTATACCTCTATCTCAT
CATGGAGTTCCTTCCTGGAGGCGATCTAATGACCATGTTGATGAAATACGACGTGTTCTCGGAAGACGTCACCCG
ATTCTACATGGCTGAATGTATCCTGGCGATCGAAGCGGTCCACAACTTGGGGTACATTCATCGGTGCGTATCTCC
CATCCCTCAGCACCCCGCAGCTCTAAACAGGAACTAGGGACATCAAGCCGGACAATGTGTTGATTGACCGGAATG
GTCACTTGAAGTTGTCGGATTTCGGTCTCTCCACTGGACTCCACAAGGCCACCGACGGAGAAATCTACAAACGGT
ATCTGGAACAAGAGAAGACCAAGGACAATTCGCGGAACAGTGTTCAAGTCAACCCCATTAACCTTACCATGAGCC
GTGAACAGATCGCGACCTGGAAGGCTAATCGACGGAAGTTGGTATGTTATACACTTCTCGTCTAACCTATATCCT
ATGTTAACTCGACCTTTACAGGCGTATTCGACGGTCGGAACTCCCGACTATGTAAGTTCCTTGCTTCGGAGCCTT
GGACTGTCCGCTCAAATGTCCTTAATAGATTGCTCCGGAAGTGTTCATGATGAAGGGCTACGGAAAGGAGTGCGA
CTGGTGGTCACTGGGTGCCATTTTCTTCGAATGCTTGGTTGGCTATGCGCCCTTCTGCTCGGACAACCCGGGGGA
TACGTACAAGAAGATCATCGACTGGCCACGTTACCTCATCTTCCCAGAAGAGGTATACATCTCCAAGGAGGGGGA
GGACCTTATTAGAGGGTATGTTCGCCTTATATATTACCTTTTGGGACATCTGAATCTTACGCTATTCGTCCTCAG
CATGATGAATTGGGCAGACAAGCGACTGACTGTGGAACAGATCAAGAACCACCCCTGGTTCTTCGGCGCCGATTG
GAACTCCCTCCGCTACATCGAACCACCATTTGTTCCCCGTCTTAGCTCGATAACGGATACCTCATATTTCCCTAC
CGACGATCTTGGCAATGTGTCCAACCAGTTGGACCAAGTGGAGAGCGTCAGTGCGGAGAAGGACCTTGCTTTCCT
CGGGTACGTAGATTCCGTTCATCTCCATTGTTCTAATCTGGACTTACTCGCCTTTGCAGATTCACATTCAAACGG
TTTACGGGTGGGCCTGGAGCCTCTGGTTAAGGGAGGTTCTGAAGCTGGAACCATCGCCTTTTGTATATTTTTTAA
AAGCGTGGAAACGTCATATTTCATCTCAATGCAAAGTTGTAAAGTCT
Length 2222