CopciAB_263750
Coprinopsis cinerea A43mutB43mut pab1-1 #326

General data

Systematic name CopciAB_263750 Strain Coprinopsis cinerea Okayama 7
Standard name - Synonyms 263750
Uniprot id Functional description Protein tyrosine kinase
Location scaffold_4:2987934..2990160 Strand +
Gene length (nt) 2227 Transcript length (nt) 2163
CDS length (nt) 1263 Protein length (aa) 420

Reciprocal best hits in model fungi

Strain name Gene / Protein name

Orthologs in mushroom models

Strain name Gene / Protein name Pident E-value Bits
Agaricus bisporus var bisporus (H97) Agabi_varbisH97_2_196107 73.5 3.62E-192 597
Agrocybe aegerita Agrae_CAA7261863 74 1.135E-191 596
Agaricus bisporus var. burnettii JB137-S8 Agabi_varbur_1_116790 73 4.123E-191 594
Hypsizygus marmoreus strain 51987-8 Hypma_RDB16681 71.1 4.416E-186 580
Schizophyllum commune H4-8 Schco3_69382 65.5 2.967E-172 540
Flammulina velutipes Flave_chr07AA00199 62.1 1.804E-157 497
Lentinula edodes B17 Lened_B_1_1_9212 63.2 2.001E-154 488
Lentinula edodes W1-26 v1.0 Lentinedodes1_4952 63.2 2.509E-154 488
Lentinula edodes NBRC 111202 Lenedo1_1042002 65.2 2.754E-153 485
Pleurotus eryngii ATCC 90797 Pleery1_1584789 58 6.153E-153 484
Ganoderma sp. 10597 SS1 v1.0 Gansp1_150064 60.5 4.215E-147 467
Grifola frondosa Grifr_OBZ70876 63.2 6.67E-132 423
Pleurotus ostreatus PC9 PleosPC9_1_84351 53.3 6.216E-112 365
Auricularia subglabra Aurde3_1_1161521 52.1 1.765E-84 286
Pleurotus ostreatus PC15 PleosPC15_2_1025103 81.3 1.137E-81 277

Expression

Name Summary Attribution Assay type
Carbon metabolism Transcriptional changes along alternative morphogenetic paths of C. cinerea Xie et al. 2020 RNA-Seq
Sample Mean cpm SD cpm Se of mean
sclerotia 114.5001 23.9723 13.8404
oidia 106.7811 17.9757 10.3783
vegetative_mycelium 76.4726 10.4814 6.0515
primordia 50.7843 4.0622 2.3453
hyphal_knot 121.7957 7.9687 4.6008
young_fruiting_body 105.8303 15.7871 9.1147
Complex carbon sources 1 (long incubation) Expression profiling on diverse complex carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Control - glucose 74.0402 8.502 4.9086
Wheat bran 41.9857 4.2112 2.4313
Horse manure 45.9811 22.9405 13.2447
Oak leaves 73.3919 8.4008 4.8502
Hay 61.8658 5.3552 3.0918
Corn stalk 58.6574 3.9805 2.2981
Pectine 49.9381 4.7899 2.7654
Microcrystalline cellulose 64.4769 8.4608 4.8849
Xylose 77.3418 8.3392 4.8146
Cellobiose 75.4775 5.8898 3.4005
Lignin 68.0752 8.4108 4.856
Apple peels 86.2409 6.0626 3.5003
Coprinopsis challenged with bacteria Transcriptional response to Bacillus subtilis and Escherichia coli. Kombrink et al. 2018 RNA-Seq
Sample Mean cpm SD cpm Se of mean
Control 43.5572 4.7987 2.7705
Bsubtilis 35.0963 1.486 0.858
Ecoli 32.5828 0.8703 0.5024
Early development 1 Time series expression profiling of basidiospore and oidium germination Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
BS 0h 178.6827 7.6399 4.4109
BS 4h 101.7713 6.3635 3.674
BS 8h 61.7023 17.2538 9.9615
BS 12h 38.8898 8.7073 5.0272
Oidia 0 h 29.6633 14.4146 8.3223
Oidia 18 h 38.7705 7.6424 4.4123
Sclerotia 80.396 11.3814 6.571
Early development 2 Time series expression profiling of mycelial growth, light induction and fruiting body initiation. Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
DM 12h 39.176 10.2871 5.9393
DM 36h 30.7155 4.0145 2.3178
DM 60h 52.3984 16.6477 9.6115
DM 84h 90.4452 13.2469 7.6481
DM 108h 106.3794 13.8511 7.9969
DM 132h 106.2285 25.7663 14.8762
DM 156hAE 104.5317 8.7877 5.0736
ELI1hAE 63.1378 10.2287 5.9056
ELI2hAE 58.8546 5.7907 3.3433
LI2hAE 69.2873 13.8406 7.9909
LI6hAE 89.4364 8.7394 5.0457
LI12hAE 75.1084 4.8239 2.7851
LI18hAE 112.4152 15.6797 9.0527
LI 24hAE 134.1541 36.5914 21.126
DM 156hAM 103.8887 27.6408 15.9584
ELI1hAM 54.72 23.452 13.54
ELI2hAM 39.7464 5.2827 3.0499
LI2hAM 26.3953 5.1141 2.9526
LI6hAM 53.7384 6.5666 3.7913
LI12hAM 109.5552 35.8742 20.712
LI18hAM 151.2562 32.5556 18.796
LI 24hAM 214.1669 42.2566 24.3969
LI 24hHK 192.8834 68.481 39.5375
L/D 6h 209.0807 36.3473 20.9851
L/D 12h 205.1648 66.3474 38.3057
L/D 18h 113.3595 32.3531 18.6791
L/D 24h 130.2815 17.2987 9.9874
Fruiting body development RNA-Seq analysis of fruiting body development Krizsan et al. 2019 RNA-Seq
Sample Mean cpm SD cpm Se of mean
Vegetative mycelium 73.4406 6.6732 3.8528
Hyphal knots 53.841 2.2207 1.2821
Primordium 1 52.6849 20.0087 11.552
Primordium 2 55.0145 14.8428 8.5695
Young Fruiting body cap 38.6157 14.1925 8.194
Younf fruiting body gill 38.8907 22.8399 13.1866
Young fruiting body stipe 45.6432 5.8537 3.3796
Mature fruiting body cap_gill 97.0048 14.4742 8.3567
Mature fruiting body stipe 258.6807 16.0594 9.2719
Nitrogen sources (12h incubation) Expression profiling on diverse nitrogen sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Complete medium - control 111.2915 9.1392 5.2765
NH4NO3 67.9954 6.4322 3.7136
Proline 65.981 5.7049 3.2937
Tryptophan 77.1515 12.0651 6.9658
Isoleucin 67.9851 0.4397 0.2539
Arginine 85.0043 4.4911 2.5929
Metionine 72.9229 5.3944 3.1144
NaNO3 68.0101 4.7609 2.7487
Plant biomass (12h incubation) Expression profiling on diverse plant biomasses as carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose - control 111.2915 9.1392 5.2765
Citrus peel 58.4264 5.62 3.2447
Poplar leaves 110.6682 5.5847 3.2243
Typha leaves 82.9739 23.9809 13.8454
Overwintered Salix leaves 80.7161 2.1439 1.2378
Reed flowering 81.0545 7.755 4.4774
Tigernut 85.1765 6.7677 3.9073
Energy cane 94.1321 20.1341 11.6244
Guar gum 107.1537 38.0412 21.9631
Apple peels 43.194 9.9317 5.7341
Cellobiose 54.5077 4.091 2.3619
Corn stalk 62.8184 11.6368 6.7185
Horse manure 77.607 15.8551 9.1539
Lignin 53.0302 30.8806 17.8289
Microcrystalline cellulose 57.5346 6.6428 3.8352
Oak leaves 69.1643 19.0922 11.0229
Pectin esterified 51.8118 11.2583 6.5
Poplar sawdust 87.9459 12.4839 7.2076
Wheat bran 54.4519 13.2973 7.6772
Chlamydomonas reinhardtii 113.2931 11.4507 6.6111
Vertatryl alcohol 127.578 18.1249 10.4644
Furfural 56.8589 10.6771 6.1644
Autoclaved mycelium 86.366 9.6378 5.5644
Simple and complex carbon and nitrogen sources Expression profiling on diverse complex carbon and nitrogen sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose control 46.4768 5.6947 3.2879
Ribose 65.1959 7.2579 4.1904
Mannose 48.3892 1.825 1.2905
Fructose 54.5282 1.9247 1.1112
Arabinose 76.2087 7.5766 4.3744
Xylose 59.0119 4.2497 2.4535
Galacturonic acid 63.3263 2.6194 1.5123
Rhamnogalacturonan 52.1153 0.9307 0.5373
Pectin esterified 48.6922 5.1519 2.9744
Polygalacturonic acid 58.6581 4.3892 2.5341
Sodium acetate 56.2085 6.3148 3.6458
No nitrogen 53.975 8.1599 4.7111
BSA 49.0973 2.9885 1.7254
Glutamine 48.8542 4.8641 2.8083
No phosphate 43.4244 3.8098 2.1996
No carbon 53.5436 5.2878 3.7391
No sulphur 43.1227 2.0762 1.1987
Simple and complex carbon sources (12h incubation) Expression profiling on diverse complex carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose - control 111.2915 9.1392 5.2765
Amylose 116.6198 10.792 6.2308
Fucose 106.1472 14.6831 8.4773
Galactose 93.1353 14.667 8.468
Lactose 78.2537 5.3918 3.113
Maltose 99.7403 9.1062 5.2575
Mannitol 80.726 8.0065 4.6225
Rhamnose 101.9772 6.0694 3.5042
Sorbitol 92.41 11.6404 6.7206
Trehalose 103.0399 7.4068 4.2763
Glycerol 93.118 9.2925 5.365
Glucuronic acid 104.1123 15.5249 8.9633
Arabinan 103.9072 30.0959 17.3759
Galactan 69.8542 12.7416 7.3564
Galactomannan 85.3167 10.7977 6.2341
Glucan 80.2877 12.8883 7.4411
Xylan 102.7386 15.7695 9.1045
Xyloglucan 125.1751 11.6745 6.7403
Arabinogalactan 102.31 6.6105 3.8166
Pectin 92.2997 48.8088 28.1798
Rhamnogalacturonan 99.213 10.5804 6.1086
Polygalacturonic acid 91.7084 9.7314 5.6184
Mannan 112.3031 11.7178 6.7653
Amylopectin 91.4382 19.1021 11.0286
Inulin 78.4349 5.3356 3.0805
BSA 102.5958 2.1981 1.2691
Starvation induced by water agar transfer Expression profiling on starvation induced by transfer to water agar Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Control 52.3984 16.6477 9.6115
2h WAT 96.255 8.2588 4.7682
4h WAT 131.3947 61.2606 35.3688
8h WAT 84.4342 48.3672 27.9248
16h WAT 80.6328 19.9828 11.5371
24h WAT 74.4285 10.9913 6.3458
WAT hyphal knot -30h 44.0605 10.7428 6.2024
WAT hyphal knot -22h 41.9075 3.1565 1.8224
WAT hyphal knot -15h 48.4647 15.2121 8.7827
WAT hyphal knot -7.5h 81.9735 26.3553 15.2162
WAT hyphal knot 64.2796 17.0273 9.8307
WAT hyphal knot +7.5h 88.9678 27.3689 15.8014
Straw time series Time series expression profiling on straw as a carbon source Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose control 30.5371 12.3711 7.1425
Straw 3h 24.9868 2.0515 1.1844
Straw 6h 22.1209 11.0549 6.3826
Straw 12h 47.6844 6.697 3.8665
Straw 24h 63.5375 22.4747 12.9758
Stress conditions 1 Expression profiling under various stress conditions Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Flask control 100.3553 11.97 6.9109
Frost (-20C, 30min) 123.6829 4.1562 2.3996
Heat shock (47C, 2h) 112.9967 17.1602 9.9075
High CO2 100.9687 15.3506 8.8627
Drought (4% agar, 12h) 141.4575 22.5116 12.9971
Oxidative (1mM H2O2, 3h) 69.1649 19.766 11.4119
Acidic (pH4, 3h) 85.5468 15.8033 9.124
Alkaline (pH9, 3h) 107.3055 11.9487 6.8986
Osmotic (sorbitol 2h) 88.6505 16.2299 9.3704
CongoRed (3h) 106.5271 11.938 6.8924
Cobalt chloride control 174.811 25.9988 15.0104
Cobalt chloride 2mM 103.3673 15.6801 9.0529
Stress conditions 2 Expression profiling under various stress conditions Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Flask control 84.5041 17.6655 10.1992
Cold stimulation 85.923 25.5485 14.7505
Scratched surface 45.104 13.0952 7.5605
Ca2+, 200mM, 24h 33.8493 14.0052 8.0859
Cu2+, 2mM, 6h 43.6368 16.8489 9.7277
Voriconazole 62.085 5.8021 3.3498
Trichoderma interaction, early 56.9373 18.1653 10.4877
Trichoderma interaction 60h 54.8925 7.7903 4.4977
Cobalt chloride 2mM repeat 36.3913 2.6341 1.5208
Hypoxia 92.2294 10.1028 5.8329
Hypoxia control 92.037 12.9204 7.4596
Protoplastation control 120.7783 1.1431 0.8083
Protoplastation 3.5h 92.0472 3.7864 2.6774
Protoplastation 1.5h 86.3678 11.3489 8.0249

General data

Systematic name -
Protein id CopciAB_263750.T0
Description Protein tyrosine kinase

Annotation summary

0 100 200 300 400 420

Conserved domains

Analysis Signature accession Signature description InterPro Accession Start End
CDD cd00180 PKc - 191 377
Pfam PF00069 Protein kinase domain IPR000719 181 363

SignalP

Prediction Start End Score
No records

Transmembrane domains

Domain n Start End Length
No records

InterPro

Accession Description
IPR011009 Protein kinase-like domain superfamily
IPR000719 Protein kinase domain

GO

Go id Term Ontology
GO:0004672 protein kinase activity MF
GO:0005524 ATP binding MF
GO:0006468 protein phosphorylation BP

KEGG

KEGG Orthology
No records

EggNOG

COG category Description
D Protein tyrosine kinase

CAZy

Class Family Subfamily
No records

Transcription factor

Group
No records

Conservation of CopciAB_263750 across fungi.

Arrow shows the origin of gene family containing CopciAB_263750.

Protein

Sequence id CopciAB_263750.T0
Sequence >CopciAB_263750.T0
MAHRPGFGRNISVQVASPTNDLKAGVVSATTGPPSARTKPMQVKRVTLTSKKNWWMVEMDEEDEVQPLNNSINSF
SSSEETAVEHEPAVVYKEYNHGIDEQVVHHHHHPSHKVEESPPPSPVYHPSRHPNSIFSFPTPTAYAAPPNATAS
LTPFAHGSASELFKCVVKKPDVIQLEINGEMQSNASDVTVQFLAELRVYTTVARHRNICAFYGCLENVGIVLEYL
ECRTLYDVIMARPPLTLAQKIDYHNQLLDGLTHLHSYRLSHGDLSLLNVQVTRDSNTIKLLDFGRSVSADSDFKS
PHDEPVDPFPYLHSRQQPKLPAVRIEQIHPGTRPFSAPEILRGECQDPLLADAYSFGMILVCLDRCECVDVKPWD
QRKDKLPGDLFENCELFEERAREYLKKWNEGRRALDKKDMIPEEI
Length 420

Coding

Sequence id CopciAB_263750.T0
Sequence >CopciAB_263750.T0
ATGGCACACCGACCAGGATTCGGCAGGAATATCAGCGTGCAGGTCGCCTCGCCGACCAACGACCTCAAGGCAGGC
GTTGTATCTGCAACCACAGGGCCGCCGTCAGCTCGAACGAAACCGATGCAAGTGAAGCGGGTGACATTGACATCG
AAGAAGAATTGGTGGATGGTGGAAATGGACGAGGAGGACGAAGTCCAGCCTCTGAACAACTCAATAAACTCTTTC
TCCTCATCGGAAGAAACAGCCGTCGAACATGAACCAGCCGTTGTCTACAAGGAATACAACCATGGAATCGACGAG
CAGGTCGTCCACCACCACCACCATCCATCCCACAAGGTCGAGGAATCGCCACCACCATCGCCAGTATATCACCCT
TCGCGGCACCCCAATTCCATCTTCTCGTTCCCAACACCGACGGCCTACGCAGCGCCCCCCAATGCGACGGCCAGT
TTAACACCATTCGCGCACGGATCAGCATCAGAATTGTTCAAATGTGTGGTGAAGAAGCCGGATGTCATTCAGCTC
GAAATCAATGGCGAGATGCAGTCGAATGCTTCAGATGTGACCGTCCAGTTCCTGGCTGAACTGCGGGTGTACACA
ACCGTCGCTCGACATCGCAATATCTGCGCTTTCTATGGCTGCTTGGAGAACGTCGGGATCGTGCTGGAGTATCTC
GAATGCCGGACGTTATACGATGTGATAATGGCCCGGCCTCCCTTAACCCTCGCTCAAAAGATCGACTATCACAAT
CAACTCCTCGACGGACTCACACACCTCCATTCATATCGGCTAAGTCACGGTGACTTGTCGTTACTGAACGTCCAG
GTCACAAGGGACTCCAACACCATCAAGTTGCTCGACTTTGGGCGTTCGGTTTCTGCGGATTCGGACTTCAAATCG
CCTCATGATGAACCCGTCGATCCGTTCCCCTACCTCCACAGCCGCCAGCAACCCAAACTTCCCGCCGTCAGGATC
GAACAGATCCACCCCGGCACCCGACCTTTCTCCGCCCCGGAGATCCTGCGAGGCGAATGCCAGGATCCTCTGCTA
GCCGATGCATATTCGTTTGGGATGATCCTTGTATGTCTGGATCGGTGCGAGTGTGTAGATGTGAAACCTTGGGAT
CAGAGGAAGGACAAGCTACCGGGCGACCTGTTCGAAAATTGCGAACTGTTCGAGGAGAGGGCGAGGGAGTACCTG
AAGAAGTGGAATGAAGGCAGACGGGCGTTGGACAAGAAGGATATGATACCGGAGGAAATTTGA
Length 1263

Transcript

Sequence id CopciAB_263750.T0
Sequence >CopciAB_263750.T0
GGCACTTTTGACTTGTACCATCTACCGCGCAAAGCGCAAACCTCGATTTATCGCCTCAGTTCTTATTTCTACCGC
TTGATTCAACTTCTCAAATGGCACACCGACCAGGATTCGGCAGGAATATCAGCGTGCAGGTCGCCTCGCCGACCA
ACGACCTCAAGGCAGGCGTTGTATCTGCAACCACAGGGCCGCCGTCAGCTCGAACGAAACCGATGCAAGTGAAGC
GGGTGACATTGACATCGAAGAAGAATTGGTGGATGGTGGAAATGGACGAGGAGGACGAAGTCCAGCCTCTGAACA
ACTCAATAAACTCTTTCTCCTCATCGGAAGAAACAGCCGTCGAACATGAACCAGCCGTTGTCTACAAGGAATACA
ACCATGGAATCGACGAGCAGGTCGTCCACCACCACCACCATCCATCCCACAAGGTCGAGGAATCGCCACCACCAT
CGCCAGTATATCACCCTTCGCGGCACCCCAATTCCATCTTCTCGTTCCCAACACCGACGGCCTACGCAGCGCCCC
CCAATGCGACGGCCAGTTTAACACCATTCGCGCACGGATCAGCATCAGAATTGTTCAAATGTGTGGTGAAGAAGC
CGGATGTCATTCAGCTCGAAATCAATGGCGAGATGCAGTCGAATGCTTCAGATGTGACCGTCCAGTTCCTGGCTG
AACTGCGGGTGTACACAACCGTCGCTCGACATCGCAATATCTGCGCTTTCTATGGCTGCTTGGAGAACGTCGGGA
TCGTGCTGGAGTATCTCGAATGCCGGACGTTATACGATGTGATAATGGCCCGGCCTCCCTTAACCCTCGCTCAAA
AGATCGACTATCACAATCAACTCCTCGACGGACTCACACACCTCCATTCATATCGGCTAAGTCACGGTGACTTGT
CGTTACTGAACGTCCAGGTCACAAGGGACTCCAACACCATCAAGTTGCTCGACTTTGGGCGTTCGGTTTCTGCGG
ATTCGGACTTCAAATCGCCTCATGATGAACCCGTCGATCCGTTCCCCTACCTCCACAGCCGCCAGCAACCCAAAC
TTCCCGCCGTCAGGATCGAACAGATCCACCCCGGCACCCGACCTTTCTCCGCCCCGGAGATCCTGCGAGGCGAAT
GCCAGGATCCTCTGCTAGCCGATGCATATTCGTTTGGGATGATCCTTGTATGTCTGGATCGGTGCGAGTGTGTAG
ATGTGAAACCTTGGGATCAGAGGAAGGACAAGCTACCGGGCGACCTGTTCGAAAATTGCGAACTGTTCGAGGAGA
GGGCGAGGGAGTACCTGAAGAAGTGGAATGAAGGCAGACGGGCGTTGGACAAGAAGGATATGATACCGGAGGAAA
TTTGAACACCTTCGCCGTTGACGGTTTTGGCCCGCCCGACTAGCCTGCTACTCCATCCTCATTCAGCCCCGCCTA
TGCCGCCGCCTATCCATCTCCCCCTGATCCTGATCACAGCCCAACTACTGACCGCAGAAACCGTTTTCTACGGAC
AAAAAGAGACGACAACGACGACGATGATGAAACCGGGGGTGCTTCCACGAACTCAGGAAAAGAAACATGACGACG
ACCCTATGTTATATACACCCAACCCCTCCCCACTATGCCGCTCAATTTATAATCGCCTCATTCGCGAAGTACGCT
ATTTCCGGAACCTTTTCGCGGAAATTATGCCATTTGTCGCTATACCGGAGTCCCGTCTGTGACCCTATTTAACCT
CTTTCGAACTCTTTCGGTTTTTCTTGGTGGCCCTTTTTTTGTTCTCTCAAGTTTCGAACTTTCCGATTCTTTGGA
ACGCTGTTGAGGGAAGGAAGGGCATATCGGGCTTGGCGGAGAGAAAGGAGAGGAGGATTGCTGCCGTGTTGGAAC
CTGAAGGGTGCTTATCTGGAGAGGCTCATTGCAGACGGAGATTTCACTTGGTACAACCTCGTAATTATTCACTGA
TCGTGTACTTCTTCCTATTGGACTTCCCCAGTCCGCTTACCTCTTGCTCATCATGGTTTGCTCTATTGTAGTCAT
TTCATTCTTGTCGTCTGTTTCCTCGGTTCGTGTGCATAATTACTACCCCTTCTCTTCCCCGTGTAGCTACTAGTG
TGACTGTTCTCTACTTTTTTGGAGCTGTTGTTACAATCGTGTAAATCACCTTGCTGGTGTTCA
Length 2163

Gene

Sequence id CopciAB_263750.T0
Sequence >CopciAB_263750.T0
GGCACTTTTGACTTGTACCATCTACCGCGCAAAGCGCAAACCTCGATTTATCGCCTCAGTTCTTATTTCTACCGC
TTGATTCAACTTCTCAAATGGCACACCGACCAGGATTCGGCAGGAATATCAGCGTGCAGGTCGCCTCGCCGACCA
ACGACCTCAAGGCAGGCGTTGTATCTGCAACCACAGGGCCGCCGTCAGCTCGAACGAAACCGATGCAAGTGAAGC
GGGTGACATTGACATCGAAGAAGAATTGGTGGATGGGCGAGTTTAATCATCCTCTAGCCTTGAGACAAGCGCATG
TCTAACCAAGCCTCGTAACATGCAGTGGAAATGGACGAGGAGGACGAAGTCCAGCCTCTGAACAACTCAATAAAC
TCTTTCTCCTCATCGGAAGAAACAGCCGTCGAACATGAACCAGCCGTTGTCTACAAGGAATACAACCATGGAATC
GACGAGCAGGTCGTCCACCACCACCACCATCCATCCCACAAGGTCGAGGAATCGCCACCACCATCGCCAGTATAT
CACCCTTCGCGGCACCCCAATTCCATCTTCTCGTTCCCAACACCGACGGCCTACGCAGCGCCCCCCAATGCGACG
GCCAGTTTAACACCATTCGCGCACGGATCAGCATCAGAATTGTTCAAATGTGTGGTGAAGAAGCCGGATGTCATT
CAGCTCGAAATCAATGGCGAGATGCAGTCGAATGCTTCAGATGTGACCGTCCAGTTCCTGGCTGAACTGCGGGTG
TACACAACCGTCGCTCGACATCGCAATATCTGCGCTTTCTATGGCTGCTTGGAGAACGTCGGGATCGTGCTGGAG
TATCTCGAATGCCGGACGTTATACGATGTGATAATGGCCCGGCCTCCCTTAACCCTCGCTCAAAAGATCGACTAT
CACAATCAACTCCTCGACGGACTCACACACCTCCATTCATATCGGCTAAGTCACGGTGACTTGTCGTTACTGAAC
GTCCAGGTCACAAGGGACTCCAACACCATCAAGTTGCTCGACTTTGGGCGTTCGGTTTCTGCGGATTCGGACTTC
AAATCGCCTCATGATGAACCCGTCGATCCGTTCCCCTACCTCCACAGCCGCCAGCAACCCAAACTTCCCGCCGTC
AGGATCGAACAGATCCACCCCGGCACCCGACCTTTCTCCGCCCCGGAGATCCTGCGAGGCGAATGCCAGGATCCT
CTGCTAGCCGATGCATATTCGTTTGGGATGATCCTTGTATGTCTGGATCGGTGCGAGTGTGTAGATGTGAAACCT
TGGGATCAGAGGAAGGACAAGCTACCGGGCGACCTGTTCGAAAATTGCGAACTGTTCGAGGAGAGGGCGAGGGAG
TACCTGAAGAAGTGGAATGAAGGCAGACGGGCGTTGGACAAGAAGGATATGATACCGGAGGAAATTTGAACACCT
TCGCCGTTGACGGTTTTGGCCCGCCCGACTAGCCTGCTACTCCATCCTCATTCAGCCCCGCCTATGCCGCCGCCT
ATCCATCTCCCCCTGATCCTGATCACAGCCCAACTACTGACCGCAGAAACCGTTTTCTACGGACAAAAAGAGACG
ACAACGACGACGATGATGAAACCGGGGGTGCTTCCACGAACTCAGGAAAAGAAACATGACGACGACCCTATGTTA
TATACACCCAACCCCTCCCCACTATGCCGCTCAATTTATAATCGCCTCATTCGCGAAGTACGCTATTTCCGGAAC
CTTTTCGCGGAAATTATGCCATTTGTCGCTATACCGGAGTCCCGTCTGTGACCCTATTTAACCTCTTTCGAACTC
TTTCGGTTTTTCTTGGTGGCCCTTTTTTTGTTCTCTCAAGTTTCGAACTTTCCGATTCTTTGGAACGCTGTTGAG
GGAAGGAAGGGCATATCGGGCTTGGCGGAGAGAAAGGAGAGGAGGATTGCTGCCGTGTTGGAACCTGAAGGGTGC
TTATCTGGAGAGGCTCATTGCAGACGGAGATTTCACTTGGTACAACCTCGTAATTATTCACTGATCGTGTACTTC
TTCCTATTGGACTTCCCCAGTCCGCTTACCTCTTGCTCATCATGGTTTGCTCTATTGTAGTCATTTCATTCTTGT
CGTCTGTTTCCTCGGTTCGTGTGCATAATTACTACCCCTTCTCTTCCCCGTGTAGCTACTAGTGTGACTGTTCTC
TACTTTTTTGGAGCTGTTGTTACAATCGTGTAAATCACCTTGCTGGTGTTCA
Length 2227