CopciAB_375402
Coprinopsis cinerea A43mutB43mut pab1-1 #326

General data

Systematic name CopciAB_375402 Strain Coprinopsis cinerea Okayama 7
Standard name - Synonyms 375402
Uniprot id Functional description Protein tyrosine kinase
Location scaffold_1:3946082..3947616 Strand -
Gene length (nt) 1535 Transcript length (nt) 1258
CDS length (nt) 858 Protein length (aa) 285

Reciprocal best hits in model fungi

Strain name Gene / Protein name

Orthologs in mushroom models

Strain name Gene / Protein name Pident E-value Bits
Lentinula edodes W1-26 v1.0 Lentinedodes1_1938 36.1 6.413E-45 164
Lentinula edodes B17 Lened_B_1_1_4505 37.1 1.197E-43 160
Hypsizygus marmoreus strain 51987-8 Hypma_RDB27269 34.5 2.005E-41 154
Agrocybe aegerita Agrae_CAA7269732 30.5 5.603E-34 132

Expression

Name Summary Attribution Assay type
Carbon metabolism Transcriptional changes along alternative morphogenetic paths of C. cinerea Xie et al. 2020 RNA-Seq
Sample Mean cpm SD cpm Se of mean
sclerotia 0.2328 0.2102 0.1213
oidia 0.282 0.2146 0.1239
vegetative_mycelium 0.6513 0.6052 0.3494
primordia 0.0236 0.0408 0.0236
hyphal_knot 0.5299 0.2397 0.1384
young_fruiting_body 0.0429 0.0744 0.0429
Complex carbon sources 1 (long incubation) Expression profiling on diverse complex carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Control - glucose 0.8319 0.7653 0.4419
Wheat bran 2.6954 2.5994 1.5008
Horse manure 4.1845 1.3344 0.7704
Oak leaves 3.7732 2.2987 1.3271
Hay 1.9565 1.8671 1.078
Corn stalk 3.3194 1.4161 0.8176
Pectine 5.3324 1.071 0.6183
Microcrystalline cellulose 5.053 3.0968 1.7879
Xylose 0.5471 0.0929 0.0536
Cellobiose 0.4947 0.1848 0.1067
Lignin 1.5126 1.5434 0.8911
Apple peels 0.5656 0.2463 0.1422
Coprinopsis challenged with bacteria Transcriptional response to Bacillus subtilis and Escherichia coli. Kombrink et al. 2018 RNA-Seq
Sample Mean cpm SD cpm Se of mean
Control 0.2833 0.0825 0.0476
Bsubtilis 0.1739 0.1658 0.0957
Ecoli 0.1502 0.2168 0.1252
Early development 1 Time series expression profiling of basidiospore and oidium germination Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
BS 0h 0.3399 0.3548 0.2048
BS 4h 0.0813 0.0814 0.047
BS 8h 0 0 0
BS 12h 0.0748 0.1295 0.0748
Oidia 0 h 0.041 0.0711 0.041
Oidia 18 h 0.0139 0.0241 0.0139
Sclerotia 0.4859 0.8416 0.4859
Early development 2 Time series expression profiling of mycelial growth, light induction and fruiting body initiation. Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
DM 12h 0.0264 0.0457 0.0264
DM 36h 0.0603 0.0238 0.0137
DM 60h 0 0 0
DM 84h 0.0873 0.086 0.0496
DM 108h 0.0566 0.098 0.0566
DM 132h 0 0 0
DM 156hAE 0.1038 0.1798 0.1038
ELI1hAE 0.0304 0.0526 0.0304
ELI2hAE 0.2038 0.1799 0.1039
LI2hAE 0.1552 0.2689 0.1552
LI6hAE 0.4281 0.4167 0.2406
LI12hAE 0.0406 0.0704 0.0406
LI18hAE 0.3647 0.415 0.2396
LI 24hAE 0.2533 0.2211 0.1276
DM 156hAM 0 0 0
ELI1hAM 0.0514 0.0774 0.0447
ELI2hAM 0 0 0
LI2hAM 0.041 0.071 0.041
LI6hAM 0.0057 0.0099 0.0057
LI12hAM 0.1886 0.2238 0.1292
LI18hAM 0.8086 0.3938 0.2274
LI 24hAM 0.0888 0.1538 0.0888
LI 24hHK 0 0 0
L/D 6h 0.2907 0.4351 0.2512
L/D 12h 0 0 0
L/D 18h 0.2985 0.4747 0.2741
L/D 24h 0.0833 0.0858 0.0495
Fruiting body development RNA-Seq analysis of fruiting body development Krizsan et al. 2019 RNA-Seq
Sample Mean cpm SD cpm Se of mean
Vegetative mycelium 0.4126 0.2093 0.1208
Hyphal knots 0.5384 0.306 0.1767
Primordium 1 0.3491 0.0418 0.0241
Primordium 2 0.2652 0.0048 0.0028
Young Fruiting body cap 0.6825 0.4806 0.2775
Younf fruiting body gill 0.0543 0.0554 0.032
Young fruiting body stipe 0.2845 0.0586 0.0338
Mature fruiting body cap_gill 1.7938 0.7098 0.4098
Mature fruiting body stipe 0.825 0.232 0.1339
Nitrogen sources (12h incubation) Expression profiling on diverse nitrogen sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Complete medium - control 0.4545 0.051 0.0294
NH4NO3 0.0775 0.0264 0.0152
Proline 0.105 0.1396 0.0806
Tryptophan 0.0154 0.0267 0.0154
Isoleucin 0.1072 0.1004 0.0579
Arginine 0.1699 0.1581 0.0913
Metionine 0.0175 0.0303 0.0175
NaNO3 0 0 0
Plant biomass (12h incubation) Expression profiling on diverse plant biomasses as carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose - control 0.4545 0.051 0.0294
Citrus peel 0 0 0
Poplar leaves 0.037 0.0641 0.037
Typha leaves 0 0 0
Overwintered Salix leaves 0.0531 0.092 0.0531
Reed flowering 0.0611 0.1059 0.0611
Tigernut 0.1231 0.1677 0.0968
Energy cane 0.1058 0.1049 0.0606
Guar gum 0.0821 0.1032 0.0596
Apple peels 0.2634 0.071 0.041
Cellobiose 0.4561 0.1148 0.0663
Corn stalk 0.7298 1.0209 0.5894
Horse manure 0.4597 0.3752 0.2166
Lignin 0.2741 0.3567 0.2059
Microcrystalline cellulose 1.4196 1.4969 0.8643
Oak leaves 0.2283 0.177 0.1022
Pectin esterified 0.259 0.0541 0.0313
Poplar sawdust 0.3247 0.2469 0.1426
Wheat bran 0.3294 0.2521 0.1455
Chlamydomonas reinhardtii 0.0498 0.0495 0.0286
Vertatryl alcohol 0.1611 0.0477 0.0275
Furfural 0.1021 0.0917 0.0529
Autoclaved mycelium 0.2347 0.1405 0.0811
Simple and complex carbon and nitrogen sources Expression profiling on diverse complex carbon and nitrogen sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose control 2.5591 0.4149 0.2395
Ribose 0.7985 0.109 0.0629
Mannose 1.4356 0.398 0.2814
Fructose 1.6845 0.504 0.291
Arabinose 1.9009 0.9297 0.5368
Xylose 1.1086 0.2756 0.1591
Galacturonic acid 1.1628 0.9592 0.5538
Rhamnogalacturonan 2.8928 0.7709 0.4451
Pectin esterified 1.2771 0.3701 0.2137
Polygalacturonic acid 4.9954 4.8742 2.8141
Sodium acetate 0.9476 0.8494 0.4904
No nitrogen 1.2322 0.3934 0.2271
BSA 1.8054 0.9151 0.5284
Glutamine 2.173 0.8431 0.4867
No phosphate 2.0276 0.9262 0.5348
No carbon 0.7236 0.6243 0.4414
No sulphur 1.6518 0.678 0.3915
Simple and complex carbon sources (12h incubation) Expression profiling on diverse complex carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose - control 0.4545 0.051 0.0294
Amylose 0.098 0.0516 0.0298
Fucose 0.0451 0.0782 0.0451
Galactose 0.1126 0.0976 0.0563
Lactose 0.0737 0.0648 0.0374
Maltose 0.2382 0.1605 0.0927
Mannitol 0.0772 0.0676 0.039
Rhamnose 0.051 0.0503 0.029
Sorbitol 0.1125 0.0179 0.0103
Trehalose 0.0822 0.0931 0.0537
Glycerol 0.1503 0.0765 0.0442
Glucuronic acid 0.0412 0.0714 0.0412
Arabinan 0.1289 0.113 0.0652
Galactan 0 0 0
Galactomannan 0.0564 0.0554 0.032
Glucan 0.3707 0.2507 0.1448
Xylan 0.0144 0.0249 0.0144
Xyloglucan 0.1012 0.1355 0.0782
Arabinogalactan 0.1465 0.1278 0.0738
Pectin 0.1985 0.1835 0.1059
Rhamnogalacturonan 0.0885 0.0877 0.0506
Polygalacturonic acid 2.3139 3.8797 2.24
Mannan 0.0377 0.0654 0.0377
Amylopectin 0.0394 0.0683 0.0394
Inulin 0.0646 0.023 0.0133
BSA 0.1151 0.1993 0.1151
Starvation induced by water agar transfer Expression profiling on starvation induced by transfer to water agar Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Control 0 0 0
2h WAT 0.0149 0.0259 0.0149
4h WAT 0.1261 0.2184 0.1261
8h WAT 0 0 0
16h WAT 0.2935 0.5083 0.2935
24h WAT 0.0083 0.0144 0.0083
WAT hyphal knot -30h 0.0876 0.1517 0.0876
WAT hyphal knot -22h 0 0 0
WAT hyphal knot -15h 0.124 0.1252 0.0723
WAT hyphal knot -7.5h 0.088 0.0839 0.0484
WAT hyphal knot 0 0 0
WAT hyphal knot +7.5h 0.2839 0.2677 0.1545
Straw time series Time series expression profiling on straw as a carbon source Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose control 0.9938 0.4518 0.2609
Straw 3h 25.1917 25.9518 14.9833
Straw 6h 28.0766 38.7972 22.3996
Straw 12h 10.5405 5.2858 3.0518
Straw 24h 0.91 1.5106 0.8722
Stress conditions 1 Expression profiling under various stress conditions Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Flask control 0.011 0.019 0.011
Frost (-20C, 30min) 0.1035 0.0912 0.0526
Heat shock (47C, 2h) 0.189 0.199 0.1149
High CO2 0.0657 0.0668 0.0386
Drought (4% agar, 12h) 0.0817 0.1415 0.0817
Oxidative (1mM H2O2, 3h) 0.0869 0.1266 0.0731
Acidic (pH4, 3h) 0.242 0.2111 0.1219
Alkaline (pH9, 3h) 0.0664 0.1033 0.0596
Osmotic (sorbitol 2h) 0.0452 0.0784 0.0452
CongoRed (3h) 0.0438 0.0759 0.0438
Cobalt chloride control 0.6174 0.3922 0.2265
Cobalt chloride 2mM 0.5301 0.3202 0.1849
Stress conditions 2 Expression profiling under various stress conditions Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Flask control 0 0 0
Cold stimulation 0.2556 0.2971 0.1715
Scratched surface 0.02 0.0173 0.01
Ca2+, 200mM, 24h 0.1949 0.2157 0.1245
Cu2+, 2mM, 6h 0 0 0
Voriconazole 0.0498 0.0863 0.0498
Trichoderma interaction, early 0 0 0
Trichoderma interaction 60h 2.0837 3.1796 1.8357
Cobalt chloride 2mM repeat 0.5327 0.5943 0.3431
Hypoxia 0.0164 0.0156 0.009
Hypoxia control 0 0 0
Protoplastation control 0 0 0
Protoplastation 3.5h 0.1021 0.1444 0.1021
Protoplastation 1.5h 0.148 0.2092 0.148

General data

Systematic name -
Protein id CopciAB_375402.T0
Description Protein tyrosine kinase

Annotation summary

0 100 200 285

Conserved domains

Analysis Signature accession Signature description InterPro Accession Start End
Pfam PF07714 Protein tyrosine and serine/threonine kinase IPR001245 14 271

SignalP

Prediction Start End Score
No records

Transmembrane domains

Domain n Start End Length
No records

InterPro

Accession Description
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domain
IPR011009 Protein kinase-like domain superfamily
IPR000719 Protein kinase domain

GO

Go id Term Ontology
GO:0004672 protein kinase activity MF
GO:0006468 protein phosphorylation BP
GO:0005524 ATP binding MF

KEGG

KEGG Orthology
No records

EggNOG

COG category Description
T Protein tyrosine kinase

CAZy

Class Family Subfamily
No records

Transcription factor

Group
No records

Conservation of CopciAB_375402 across fungi.

Arrow shows the origin of gene family containing CopciAB_375402.

Protein

Sequence id CopciAB_375402.T0
Sequence >CopciAB_375402.T0
MPYRDFGPYTDVLDATHNCQKAVVKVFRIGKLSPHHRHVLTKRLENALTEWKRHHMHPNIARVTGMVLGFGDLPG
IEMPLYSNGNAYRYLKAHPNVDKYRLICGIAEGLNHLHSQQPPIIHGMVCATNILISDSGAPLLTDIGLGTIPLE
AVGVSPFQGDKYSRHLQKVRWLAPEIIDPENVGPPDISTSLNDCTPSTDVYSFGMTILELFTEKVPYHHVRSTPA
VINEINNRRHPGRLYCTEVPDELWCILESCWSHHAKERPTTAVLRSRIGALGIHGSGRRA
Length 285

Coding

Sequence id CopciAB_375402.T0
Sequence >CopciAB_375402.T0
ATGCCGTATCGTGACTTCGGGCCCTACACAGACGTCCTCGACGCGACCCACAACTGTCAGAAAGCAGTTGTCAAA
GTCTTTCGGATTGGAAAGCTCTCTCCTCACCACCGACATGTACTGACTAAGAGGCTAGAGAATGCGTTGACGGAG
TGGAAGAGGCATCACATGCACCCTAACATTGCCAGAGTAACGGGAATGGTTCTCGGTTTCGGGGATCTTCCTGGT
ATCGAAATGCCTCTGTACAGCAACGGGAATGCATACAGATATCTCAAGGCCCATCCAAATGTCGACAAGTACCGC
TTGATCTGTGGGATTGCTGAGGGACTAAACCACCTGCATTCCCAACAACCACCCATCATACACGGCATGGTGTGC
GCGACGAACATCTTAATCTCTGACTCGGGCGCCCCTCTGCTGACTGACATTGGTCTCGGAACAATTCCTCTAGAA
GCTGTCGGAGTTTCGCCGTTCCAAGGTGATAAGTATTCTCGACATCTTCAGAAAGTTAGGTGGCTTGCCCCCGAG
ATAATTGATCCAGAGAACGTGGGTCCCCCTGATATTAGTACGAGCTTAAACGATTGCACACCATCGACAGATGTC
TACAGCTTTGGGATGACTATCCTGGAGCTATTCACCGAGAAGGTGCCATACCACCATGTCAGATCTACTCCTGCT
GTAATCAACGAAATAAACAACCGCCGCCATCCAGGCCGATTGTACTGCACCGAGGTGCCTGACGAGCTATGGTGC
ATCCTTGAAAGCTGCTGGAGTCATCACGCGAAGGAGCGACCAACCACTGCGGTCCTGCGCTCGCGGATAGGGGCT
CTCGGCATACACGGCAGCGGCCGGAGGGCTTAG
Length 858

Transcript

Sequence id CopciAB_375402.T0
Sequence >CopciAB_375402.T0
AGAGTCTACGACCATTCTACCTCGACGACGGGCGTCTAACAAGGCGCCTTCCATATGATTCGAACGTCGTCCTAT
ACTTGTGTGTCTGGGACTGCGGAAGCTGTTACTAGGAGGGCTATATAGCCAGCTCCTGCTCACCCTTCCTTGCTG
TAAACACCCACCCACCCATACATGCACACATTCACAATTATCAGGTCGACTTCCACCACGATATCACTACAAGCG
CTTACCGACTCTCGGATCGAGGGTTGAAATTACAGCTGGACATGCCGTATCGTGACTTCGGGCCCTACACAGACG
TCCTCGACGCGACCCACAACTGTCAGAAAGCAGTTGTCAAAGTCTTTCGGATTGGAAAGCTCTCTCCTCACCACC
GACATGTACTGACTAAGAGGCTAGAGAATGCGTTGACGGAGTGGAAGAGGCATCACATGCACCCTAACATTGCCA
GAGTAACGGGAATGGTTCTCGGTTTCGGGGATCTTCCTGGTATCGAAATGCCTCTGTACAGCAACGGGAATGCAT
ACAGATATCTCAAGGCCCATCCAAATGTCGACAAGTACCGCTTGATCTGTGGGATTGCTGAGGGACTAAACCACC
TGCATTCCCAACAACCACCCATCATACACGGCATGGTGTGCGCGACGAACATCTTAATCTCTGACTCGGGCGCCC
CTCTGCTGACTGACATTGGTCTCGGAACAATTCCTCTAGAAGCTGTCGGAGTTTCGCCGTTCCAAGGTGATAAGT
ATTCTCGACATCTTCAGAAAGTTAGGTGGCTTGCCCCCGAGATAATTGATCCAGAGAACGTGGGTCCCCCTGATA
TTAGTACGAGCTTAAACGATTGCACACCATCGACAGATGTCTACAGCTTTGGGATGACTATCCTGGAGCTATTCA
CCGAGAAGGTGCCATACCACCATGTCAGATCTACTCCTGCTGTAATCAACGAAATAAACAACCGCCGCCATCCAG
GCCGATTGTACTGCACCGAGGTGCCTGACGAGCTATGGTGCATCCTTGAAAGCTGCTGGAGTCATCACGCGAAGG
AGCGACCAACCACTGCGGTCCTGCGCTCGCGGATAGGGGCTCTCGGCATACACGGCAGCGGCCGGAGGGCTTAGT
AACGTGTGCCGTAGGCCCGCGGTAGGGACAAAAACAGCCCGAAAGAGGAACTCCGACTCGGAGACTGAATTTCTG
GTATATAAACCCTGACGTCGTTGTCTACGATCGCAATGCAATTTTGCTTTACACCATC
Length 1258

Gene

Sequence id CopciAB_375402.T0
Sequence >CopciAB_375402.T0
AGAGTCTACGACCATTCTACCTCGACGACGGGCGTCTAACAAGGCGCCTTCCATATGATTCGAACGTCGTCCTAT
ACTTGTGTGTCTGGGACTGCGGAAGCTGTTACTAGGAGGGCTATATAGCCAGCTCCTGCTCACCCTTCCTTGCTG
TAAACACCCACCCACCCATACATGCACACATTCACAATTATCAGGTATATCCTTCAACGCATCCAATATCTCAAG
CTAAATGTTGTCTTAGGTCGACTTCCACCACGATATCACTACAAGCGCTTACCGACTCTCGGATCGAGGGTTGAA
ATTACAGCTGGACATGCCGTATCGTGACTTCGGGCCCTACACAGACGTCCTCGACGCGACCCACAACTGTCAGAA
AGCAGTTGTCAAAGTCTTTCGGATTGGAAAGCTCTCTCCTCACCACCGACATGTACTGACTAAGGTATGTGTATT
TCGGTCAAAAAGAATCCATCGAGCGGTTTGGCTATATCGTAACATATGCAGAGGCTAGAGAATGCGTTGACGGAG
TGGAAGAGGCATCACATGCACCCTAACATTGCCAGAGTAACGGGAATGGTTCTCGGTTTCGGGGATCTTCCTGGT
ATCGAAATGCCTCTGTACAGCAACGGGAATGCATACAGATATCTCAAGGCCCATCCAAATGTCGACAAGTACCGC
TTGGTAGGTGGTCAATACGTGAATTGGGAGTCGCTGTGCATAATCTGACGCCCACGGAAGATCTGTGGGATTGCT
GAGGGACTAAACCACCTGCATTCCCAACAACCACCCATCATACACGGCATGGTGTGCGCGGTGAGTATGTTTCAC
TCACTTTCATTCTAGCCCCTGACAGATACTCCTCAGACGAACATCTTAATCTCTGACTCGGGCGCCCCTCTGCTG
ACTGACATTGGTCTCGGAACAATTCCTCTAGAAGCTGTCGGAGTTTCGCCGTTCCAAGGTGATAAGTATTCTCGA
CATCTTCAGAAAGTTAGGTGGCTTGCCCCCGAGATAATTGATCCAGAGAACGTGGGTCCCCCTGATATTAGTACG
AGCTTAAACGATTGCACACCATCGACAGATGTCTACAGCTTTGGGATGACTATCCTGGAGGTCCGTCTACAACGT
GATTGATAAGTATTAAGCGCTGGTCAACTAACACCCGATCCACAGCTATTCACCGAGAAGGTGCCATACCACCAT
GTCAGATCTACTCCTGCTGTAATCAACGAAATAAACAACCGCCGCCATCCAGGCCGATTGTACTGCACCGAGGTG
CCTGACGAGCTATGGTGCATCCTTGAAAGCTGCTGGAGTCATCACGCGAAGGAGCGACCAACCACTGCGGTCCTG
CGCTCGCGGATAGGGGCTCTCGGCATACACGGCAGCGGCCGGAGGGCTTAGTAACGTGTGCCGTAGGCCCGCGGT
AGGGACAAAAACAGCCCGAAAGAGGAACTCCGACTCGGAGACTGAATTTCTGGTATATAAACCCTGACGTCGTTG
TCTACGATCGCAATGCAATTTTGCTTTACACCATC
Length 1535