CopciAB_449305
Coprinopsis cinerea A43mutB43mut pab1-1 #326

General data

Systematic name CopciAB_449305 Strain Coprinopsis cinerea Okayama 7
Standard name HOG1 Synonyms 449305
Uniprot id Functional description mitogen-activated protein kinase
Location scaffold_1:1035862..1038225 Strand -
Gene length (nt) 2364 Transcript length (nt) 1658
CDS length (nt) 1107 Protein length (aa) 368

Reciprocal best hits in model fungi

Strain name Gene / Protein name
Ustilago maydis HOG1
Cryptococcus neoformans HOG1
Fusarium graminearum HOG1
Aspergillus nidulans AN1017_hogA
Schizosaccharomyces pombe sty1
Candida albicans HOG1
Saccharomyces cerevisiae YLR113W_HOG1

Orthologs in mushroom models

Strain name Gene / Protein name Pident E-value Bits
Agrocybe aegerita Agrae_CAA7265857 93.4 6.901E-233 712
Hypsizygus marmoreus strain 51987-8 Hypma_RDB28928 93.6 4.204E-231 707
Pleurotus eryngii ATCC 90797 Pleery1_1456625 92 3.948E-230 704
Pleurotus ostreatus PC15 PleosPC15_2_38836 91.8 3.68E-229 701
Pleurotus ostreatus PC9 PleosPC9_1_86234 91.8 3.603E-229 701
Lentinula edodes NBRC 111202 Lenedo1_321976 91.6 1.257E-225 691
Lentinula edodes W1-26 v1.0 Lentinedodes1_17686 91.6 1.248E-225 691
Ganoderma sp. 10597 SS1 v1.0 Gansp1_39761 91.1 2.564E-225 690
Agaricus bisporus var bisporus (H97) Agabi_varbisH97_2_41003 96.1 2.266E-224 687
Agaricus bisporus var. burnettii JB137-S8 Agabi_varbur_1_22411 96.1 2.361E-224 687
Flammulina velutipes Flave_chr08AA00335 91.6 2.826E-224 687
Schizophyllum commune H4-8 Schco3_2175896 89.1 7.718E-224 686
Grifola frondosa Grifr_OBZ66023 88.8 3.373E-222 681
Auricularia subglabra Aurde3_1_1217468 85.9 1.24E-213 657
Lentinula edodes B17 Lened_B_1_1_10934 84.2 3.679E-202 623

Expression

Name Summary Attribution Assay type
Carbon metabolism Transcriptional changes along alternative morphogenetic paths of C. cinerea Xie et al. 2020 RNA-Seq
Sample Mean cpm SD cpm Se of mean
sclerotia 547.0886 201.4035 116.2804
oidia 205.7932 31.9737 18.4601
vegetative_mycelium 214.5632 120.8144 69.7522
primordia 111.274 10.9938 6.3473
hyphal_knot 361.3564 57.5379 33.2195
young_fruiting_body 254.3141 58.9542 34.0372
Complex carbon sources 1 (long incubation) Expression profiling on diverse complex carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Control - glucose 261.2157 12.5206 7.2288
Wheat bran 215.159 62.722 36.2126
Horse manure 230.43 22.6285 13.0646
Oak leaves 253.2348 104.1235 60.1157
Hay 243.1039 36.5325 21.092
Corn stalk 249.8084 49.4757 28.5648
Pectine 209.956 12.065 6.9657
Microcrystalline cellulose 242.6979 64.8463 37.439
Xylose 353.8053 37.2122 21.4845
Cellobiose 224.7183 33.0646 19.0899
Lignin 316.8054 178.1471 102.8533
Apple peels 345.777 26.9044 15.5333
Coprinopsis challenged with bacteria Transcriptional response to Bacillus subtilis and Escherichia coli. Kombrink et al. 2018 RNA-Seq
Sample Mean cpm SD cpm Se of mean
Control 400.3072 255.0734 147.2667
Bsubtilis 1462.6949 200.3202 115.6549
Ecoli 630.0272 201.9386 116.5893
Early development 1 Time series expression profiling of basidiospore and oidium germination Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
BS 0h 125.397 23.5051 13.5707
BS 4h 130.803 28.2665 16.3197
BS 8h 112.7618 7.4118 4.2792
BS 12h 180.1166 31.3216 18.0835
Oidia 0 h 60.1893 4.5103 2.604
Oidia 18 h 187.8911 55.0369 31.7756
Sclerotia 237.7127 32.7302 18.8968
Early development 2 Time series expression profiling of mycelial growth, light induction and fruiting body initiation. Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
DM 12h 290.319 116.0471 66.9998
DM 36h 137.7011 52.6003 30.3688
DM 60h 164.9305 50.2706 29.0238
DM 84h 200.9381 59.3818 34.2841
DM 108h 166.0958 4.3638 2.5194
DM 132h 271.3355 175.6127 101.3901
DM 156hAE 298.7476 22.1842 12.808
ELI1hAE 139.2283 22.7316 13.1241
ELI2hAE 145.4969 23.6913 13.6782
LI2hAE 152.2622 18.9654 10.9497
LI6hAE 300.9392 87.1994 50.3446
LI12hAE 194.6591 35.3623 20.4165
LI18hAE 232.9833 51.5109 29.7398
LI 24hAE 274.4043 41.6626 24.0539
DM 156hAM 184.387 29.3016 16.9173
ELI1hAM 103.597 24.722 14.2732
ELI2hAM 106.2223 23.7467 13.7102
LI2hAM 79.0223 16.1288 9.312
LI6hAM 201.3773 37.6137 21.7163
LI12hAM 192.4796 34.4228 19.874
LI18hAM 227.0597 62.5672 36.1232
LI 24hAM 386.4043 235.1731 135.7772
LI 24hHK 293.1006 91.6327 52.9042
L/D 6h 318.6085 39.1226 22.5874
L/D 12h 306.7967 48.7868 28.1671
L/D 18h 260.2924 118.7073 68.5357
L/D 24h 195.0068 39.5638 22.8421
Fruiting body development RNA-Seq analysis of fruiting body development Krizsan et al. 2019 RNA-Seq
Sample Mean cpm SD cpm Se of mean
Vegetative mycelium 406.1328 345.2506 199.3305
Hyphal knots 1654.9117 1987.2795 1147.3563
Primordium 1 238.4162 55.8272 32.2319
Primordium 2 343.7359 252.4336 145.7426
Young Fruiting body cap 755.256 683.0849 394.3792
Younf fruiting body gill 181.4029 52.0571 30.0552
Young fruiting body stipe 329.0302 82.3925 47.5694
Mature fruiting body cap_gill 1934.7768 802.5675 463.3626
Mature fruiting body stipe 1639.9457 235.3275 135.8664
Nitrogen sources (12h incubation) Expression profiling on diverse nitrogen sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Complete medium - control 348.3414 50.195 28.9801
NH4NO3 303.7626 77.218 44.5818
Proline 518.4841 241.4351 139.3926
Tryptophan 736.1655 258.2177 149.082
Isoleucin 343.8902 202.8083 117.0914
Arginine 448.707 1.7849 1.0305
Metionine 581.4929 100.5661 58.0619
NaNO3 357.1915 49.1905 28.4002
Plant biomass (12h incubation) Expression profiling on diverse plant biomasses as carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose - control 348.3414 50.195 28.9801
Citrus peel 600.4018 10.4041 6.0068
Poplar leaves 316.7147 13.1183 7.5738
Typha leaves 266.8632 74.4182 42.9653
Overwintered Salix leaves 321.2564 101.1662 58.4083
Reed flowering 327.5193 142.0568 82.0166
Tigernut 320.8384 62.3496 35.9976
Energy cane 409.7551 69.9423 40.3812
Guar gum 348.193 286.8517 165.6139
Apple peels 299.9463 8.854 5.1118
Cellobiose 170.9144 39.0888 22.568
Corn stalk 239.3974 3.8416 2.218
Horse manure 403.5884 99.4059 57.392
Lignin 616.7312 399.2822 230.5257
Microcrystalline cellulose 546.7077 159.9227 92.3314
Oak leaves 234.0928 31.9796 18.4634
Pectin esterified 418.44 31.033 17.9169
Poplar sawdust 194.3712 48.8179 28.185
Wheat bran 252.4421 80.6642 46.5715
Chlamydomonas reinhardtii 351.4707 47.8 27.5973
Vertatryl alcohol 247.2876 19.164 11.0644
Furfural 375.5121 27.4104 15.8254
Autoclaved mycelium 394.6675 47.4402 27.3896
Simple and complex carbon and nitrogen sources Expression profiling on diverse complex carbon and nitrogen sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose control 212.4295 20.5 11.8357
Ribose 347.9879 98.1173 56.648
Mannose 251.3635 6.6218 4.6823
Fructose 275.1435 38.7676 22.3825
Arabinose 283.9665 36.9585 21.338
Xylose 214.3674 8.6084 4.97
Galacturonic acid 306.0837 34.3693 19.8431
Rhamnogalacturonan 269.2166 12.2879 7.0944
Pectin esterified 566.9668 158.2907 91.3892
Polygalacturonic acid 236.3622 8.8583 5.1143
Sodium acetate 454.8915 79.4926 45.8951
No nitrogen 274.3296 66.4474 38.3634
BSA 423.8319 134.6521 77.7414
Glutamine 283.6854 13.0387 7.5279
No phosphate 249.5928 25.9672 14.9921
No carbon 520.505 48.3209 34.168
No sulphur 292.5004 61.8203 35.6919
Simple and complex carbon sources (12h incubation) Expression profiling on diverse complex carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose - control 348.3414 50.195 28.9801
Amylose 332.1972 30.2329 17.455
Fucose 415.8122 32.0496 18.5038
Galactose 767.9889 85.831 49.5545
Lactose 258.336 24.7723 14.3023
Maltose 419.5014 177.9471 102.7378
Mannitol 313.6191 73.5936 42.4893
Rhamnose 412.1163 183.3492 105.8567
Sorbitol 232.1499 32.347 18.6756
Trehalose 268.073 82.5969 47.6873
Glycerol 625.4979 293.8263 169.6407
Glucuronic acid 306.37 88.2645 50.9595
Arabinan 253.3359 171.5604 99.0505
Galactan 395.2018 109.6711 63.3187
Galactomannan 341.0673 30.9497 17.8688
Glucan 411.6776 36.8448 21.2724
Xylan 197.8251 54.5214 31.4779
Xyloglucan 187.2725 31.5893 18.2381
Arabinogalactan 313.4445 17.8946 10.3314
Pectin 560.9286 95.8575 55.3434
Rhamnogalacturonan 463.525 61.6732 35.607
Polygalacturonic acid 347.9171 27.2333 15.7231
Mannan 295.401 71.0218 41.0045
Amylopectin 548.4052 338.5842 195.4817
Inulin 1005.2941 85.4498 49.3345
BSA 600.5145 90.6399 52.331
Starvation induced by water agar transfer Expression profiling on starvation induced by transfer to water agar Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Control 164.9305 50.2706 29.0238
2h WAT 354.244 193.2413 111.5679
4h WAT 165.2061 36.2317 20.9184
8h WAT 170.9552 8.5213 4.9198
16h WAT 191.362 45.8044 26.4452
24h WAT 186.497 11.9853 6.9197
WAT hyphal knot -30h 91.8517 9.2809 5.3583
WAT hyphal knot -22h 93.9628 6.9155 3.9926
WAT hyphal knot -15h 116.3339 12.7694 7.3724
WAT hyphal knot -7.5h 265.3169 85.2783 49.2354
WAT hyphal knot 186.3553 76.1385 43.9586
WAT hyphal knot +7.5h 257.8276 47.8926 27.6508
Straw time series Time series expression profiling on straw as a carbon source Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose control 385.8985 117.0918 67.603
Straw 3h 801.8517 499.6909 288.4966
Straw 6h 846.7875 131.5719 75.9631
Straw 12h 396.5958 83.6012 48.2672
Straw 24h 626.2478 325.5471 187.9547
Stress conditions 1 Expression profiling under various stress conditions Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Flask control 509.036 126.2309 72.8794
Frost (-20C, 30min) 308.4312 107.0633 61.813
Heat shock (47C, 2h) 210.4769 14.6348 8.4494
High CO2 207.1115 83.1472 48.005
Drought (4% agar, 12h) 119.7491 19.8187 11.4423
Oxidative (1mM H2O2, 3h) 537.6753 185.6732 107.1985
Acidic (pH4, 3h) 671.6609 133.8423 77.2739
Alkaline (pH9, 3h) 291.7776 66.1512 38.1924
Osmotic (sorbitol 2h) 697.5254 148.4472 85.706
CongoRed (3h) 583.3552 24.1738 13.9568
Cobalt chloride control 292.1791 72.1551 41.6587
Cobalt chloride 2mM 370.927 64.0582 36.984
Stress conditions 2 Expression profiling under various stress conditions Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Flask control 144.8347 80.969 46.7475
Cold stimulation 231.2768 33.6776 19.4438
Scratched surface 51.367 12.2024 7.045
Ca2+, 200mM, 24h 208.1665 15.9477 9.2074
Cu2+, 2mM, 6h 576.7011 282.6473 163.1865
Voriconazole 196.9241 4.181 2.4139
Trichoderma interaction, early 199.6517 61.9786 35.7833
Trichoderma interaction 60h 167.5232 8.2285 4.7507
Cobalt chloride 2mM repeat 181.7412 47.3603 27.3435
Hypoxia 249.1721 129.1825 74.5835
Hypoxia control 292.6886 111.6132 64.4399
Protoplastation control 1054.411 2.1519 1.5216
Protoplastation 3.5h 1396.8824 15.7374 11.128
Protoplastation 1.5h 1765.3925 251.44 177.795

General data

Systematic name HOG1
Protein id CopciAB_449305.T0
Description mitogen-activated protein kinase

Annotation summary

0 100 200 300 368

Conserved domains

Analysis Signature accession Signature description InterPro Accession Start End
CDD cd07856 STKc_Sty1_Hog1 IPR038783 8 335
Pfam PF00069 Protein kinase domain IPR000719 19 298

SignalP

Prediction Start End Score
No records

Transmembrane domains

Domain n Start End Length
No records

InterPro

Accession Description
IPR017441 Protein kinase, ATP binding site
IPR000719 Protein kinase domain
IPR011009 Protein kinase-like domain superfamily
IPR038783 Fungal mitogen-activated protein (MAP) kinase Sty1/Hog1
IPR003527 Mitogen-activated protein (MAP) kinase, conserved site
IPR008271 Serine/threonine-protein kinase, active site

GO

Go id Term Ontology
GO:0005524 ATP binding MF
GO:0004672 protein kinase activity MF
GO:0006468 protein phosphorylation BP
GO:0004707 MAP kinase activity MF
GO:0051403 stress-activated MAPK cascade BP

KEGG

KEGG Orthology
K04441

EggNOG

COG category Description
T mitogen-activated protein kinase

CAZy

Class Family Subfamily
No records

Transcription factor

Group
No records

Conservation of CopciAB_449305 across fungi.

Arrow shows the origin of gene family containing CopciAB_449305.

Protein

Sequence id CopciAB_449305.T0
Sequence >CopciAB_449305.T0
MSFVKLSIFGTSFEVTTRYVDLQPVGMGAFGLVCSAKDQLTGASVAIKKIMKPFSTPVLAKRTYRELKLLKHIQH
ENIISLSDVFISPLEDLYFVTELLGTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGVVHRDLKPSNILVNE
NCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVAVDIWSTGCIFAEMLEGKPLFPGKDHVNQFSII
TELLGTPPDDVIETICSENTLRFVQSLPKRQRVPFSQKLRTTDPDALDLLERMLVFDPRKRINASESLAHAYVAP
YHDPTDEPEAEEKFDWSFNDADLPIDTWKVMMYSEILDFHQVDQGQGLGIPEGALAGPEDGGYSNGHA
Length 368

Coding

Sequence id CopciAB_449305.T0
Sequence >CopciAB_449305.T0
ATGTCCTTCGTCAAACTCAGCATATTCGGAACATCCTTCGAGGTTACAACTCGATATGTTGACCTCCAGCCAGTG
GGAATGGGCGCTTTCGGTCTCGTCTGCTCAGCGAAAGATCAACTAACAGGAGCATCTGTCGCTATCAAGAAGATC
ATGAAACCTTTCAGCACACCGGTCCTCGCCAAGCGAACGTACCGCGAACTCAAGCTCTTGAAGCACATCCAACAC
GAAAACATTATCAGCCTCAGCGACGTCTTCATCTCCCCACTGGAGGATCTGTACTTTGTCACAGAGCTCCTCGGA
ACTGACCTTCACCGCCTGTTAACGTCGAGACCACTCGAAAAGCAGTTCATTCAATACTTCTTGTACCAAATCTTG
CGTGGCCTAAAATACGTTCATTCAGCGGGTGTCGTCCATCGTGACCTCAAACCGAGCAATATCCTCGTGAACGAA
AACTGTGATCTGAAGATTTGCGATTTCGGATTGGCTCGTATCCAGGATCCGCAAATGACTGGCTACGTCTCGACA
CGATACTACCGGGCGCCAGAGATCATGCTAACATGGCAGAAGTATGACGTTGCCGTCGACATCTGGAGTACTGGG
TGCATATTTGCAGAGATGCTTGAGGGCAAACCGCTCTTCCCAGGGAAAGATCACGTTAACCAATTCTCGATCATC
ACGGAATTATTGGGCACACCTCCTGATGATGTCATTGAAACCATCTGCAGCGAAAACACCCTGCGCTTTGTCCAA
AGCTTGCCTAAGCGGCAACGTGTTCCTTTCAGCCAGAAACTGCGGACGACAGACCCAGATGCACTTGATCTCCTT
GAGCGGATGCTCGTGTTCGACCCGCGCAAGCGGATAAACGCGTCTGAGTCACTTGCTCATGCCTACGTCGCACCT
TATCATGATCCTACCGACGAGCCGGAAGCGGAAGAGAAATTTGATTGGAGCTTCAATGACGCCGATCTTCCTATC
GATACCTGGAAAGTCATGATGTACAGTGAAATCCTCGACTTCCATCAGGTCGATCAAGGGCAGGGGCTGGGCATC
CCAGAAGGAGCGCTGGCTGGTCCAGAGGATGGGGGCTACTCGAATGGCCATGCTTGA
Length 1107

Transcript

Sequence id CopciAB_449305.T0
Sequence >CopciAB_449305.T0
ACAGGCTTCTTCCTACCACCATCTCCTCCACAATACGCCCAACGTTCTCCCGTTGAGCGCGATCCTCCCTTCTTC
TACCAGCCTATACAGAACTCGTCGTCACCCAAGTCCTTCTCCTCCTCAACGTCAACGACGTCGAGTACAATGTCC
TTCGTCAAACTCAGCATATTCGGAACATCCTTCGAGGTTACAACTCGATATGTTGACCTCCAGCCAGTGGGAATG
GGCGCTTTCGGTCTCGTCTGCTCAGCGAAAGATCAACTAACAGGAGCATCTGTCGCTATCAAGAAGATCATGAAA
CCTTTCAGCACACCGGTCCTCGCCAAGCGAACGTACCGCGAACTCAAGCTCTTGAAGCACATCCAACACGAAAAC
ATTATCAGCCTCAGCGACGTCTTCATCTCCCCACTGGAGGATCTGTACTTTGTCACAGAGCTCCTCGGAACTGAC
CTTCACCGCCTGTTAACGTCGAGACCACTCGAAAAGCAGTTCATTCAATACTTCTTGTACCAAATCTTGCGTGGC
CTAAAATACGTTCATTCAGCGGGTGTCGTCCATCGTGACCTCAAACCGAGCAATATCCTCGTGAACGAAAACTGT
GATCTGAAGATTTGCGATTTCGGATTGGCTCGTATCCAGGATCCGCAAATGACTGGCTACGTCTCGACACGATAC
TACCGGGCGCCAGAGATCATGCTAACATGGCAGAAGTATGACGTTGCCGTCGACATCTGGAGTACTGGGTGCATA
TTTGCAGAGATGCTTGAGGGCAAACCGCTCTTCCCAGGGAAAGATCACGTTAACCAATTCTCGATCATCACGGAA
TTATTGGGCACACCTCCTGATGATGTCATTGAAACCATCTGCAGCGAAAACACCCTGCGCTTTGTCCAAAGCTTG
CCTAAGCGGCAACGTGTTCCTTTCAGCCAGAAACTGCGGACGACAGACCCAGATGCACTTGATCTCCTTGAGCGG
ATGCTCGTGTTCGACCCGCGCAAGCGGATAAACGCGTCTGAGTCACTTGCTCATGCCTACGTCGCACCTTATCAT
GATCCTACCGACGAGCCGGAAGCGGAAGAGAAATTTGATTGGAGCTTCAATGACGCCGATCTTCCTATCGATACC
TGGAAAGTCATGATGTACAGTGAAATCCTCGACTTCCATCAGGTCGATCAAGGGCAGGGGCTGGGCATCCCAGAA
GGAGCGCTGGCTGGTCCAGAGGATGGGGGCTACTCGAATGGCCATGCTTGATCGCTGACATTTTCTCCCTGGATC
TCTTCTTTGTCTCGGGTTATGTCTATTTCTTGATTTTTGTGAGTTCCAAGGTTAGGACCCCGCGCCAACAACTTC
AACATCCAATCAAGCTCGACGATACGTGTATTCTAATCGCCATTGCCGTCTCTGTCTCTAAGCCACCTCATTTGT
ATTTTGTGTATATCTCTCCCTTGCCATGTTGTGCGCCTCTAGTACCATGTTTTACCCGGACTTACTTCCTCGTTC
ATCTGTCTCTGTTGTTTTTACTTCTCTGATACACGGTCGCTTTTCCGGCGGCACATAGCCTTTGCTTGTTCCTTA
CCTCGGGGTTTCTTACGCCTTGGCTCGCGTACTTGTATATTCTTCACTATTGGATCTGAAAATGTCAATTTAAAT
GGAACTTC
Length 1658

Gene

Sequence id CopciAB_449305.T0
Sequence >CopciAB_449305.T0
ACAGGCTTCTTCCTACCACCATCTCCTCCACAATACGCCCAACGTTCTCCCGTTGAGCGCGATCCTCCCTTCTTC
TACCAGCCTATACAGAACTCGTCGTCACCCAAGTCCTTCTCCTCCTCAACGTCAACGACGTCGAGTACAATGTCC
TTCGTCAAACTCAGCATATTCGGAACATCCTTCGAGGTTAGGATCCATGGACTAGGGCGGCCATTAGGATGCTCA
TGACCTACGTTTACCGCAGGTTACAACTCGATATGTTGACCTCCAGCCAGTGGGAATGGGTACGTCGCCTGACTG
ACTGGGGAGCCACCGATGGGTACTGATCTCTCTCCTGTCGATAGGCGCTTTCGGTCTCGTCTGGTCAGTTAGGCC
TCCACAGCATCTCGTATGAAAGGCGACATTGACATCGTCTTCAGCTCAGCGAAAGATCAACTAACAGGAGCATCT
GTCGCTATCAAGAAGATCATGAAACCTTTCAGCACACCGGTCCTCGCCAAGCGAACGTACCGCGAACTCAAGCTC
TTGAAGCACATCCAACACGAAAACGTAGCCCCGACCTTATTCAAGCGTGCTATCCGCTGACCCTTCTTACAGATT
ATCAGCCTCAGCGACGTCTTCATCTCCCCACTGGAGGATCTGTACGTTTCCCCCTTTGGGTTACTTCCTCAACCC
AGCAGTAACGCTCGTATCCAGGTACTTTGTCACAGAGCTCCTCGGAACTGACCTTCACCGCCTGTTAACGTCGAG
ACCACTCGAAAAGCAGTTCATTCAATACTTCTTGTACCAAATCTTGGTGCGTTATCTTGTCGATATCCGGGATAG
ACACTGATCTGCTATCCAACAGCGTGGCCTAAAATACGTTCATTCAGCGGGTGTCGTCCATCGTGACCTCGTATG
TTCATTCATCGTCTCCCCTTCACACCCAAACTCAACGACGGAGCCGAATAGAAACCGAGCAATATCCTCGTGAAC
GAAAACTGTGATCTGAAGGTATGGTTCCCCGAGCAATGGAAAGCTTATTGGGCGCTTGGTCTGACCCACAGCCCT
GCCGTTCCCTAGATTTGCGATTTCGGATTGGCTCGTATCCAGGATCCGCAAATGACTGGCTACGTCTCGACACGA
TACTACCGGGCGCCAGAGATCATGCTAACATGGCAGAAGTATGACGTTGCCGTCGACATCTGGAGTACTGGGTGC
ATATTTGCAGAGATGCTTGAGGGCAAACCGCTCTTCCCAGGGAAAGATCGTACGTCATATCGCGGGCCACAACAC
ATTCCTCTCCCTGACATATGCCCCTCCCTTCACTTTAGACGTTAACCAATTCTCGATCATCACGGAATTATTGGG
CACACCTCCTGATGATGTCATTGAAACCATCTGCAGCGAAAACGTAGGCGTTGCTCCATGTCGTTTGACCAGCTG
ATTGCAGTCCTGACCCTCAAATGTTCGTCCGTTAGACCCTGCGCTTTGTCCAAAGCTTGCCTAAGCGGCAACGTG
TTCCTTTCAGCCAGAAACTGCGGACGACAGACCCAGATGGTAAGATTTGTGTGACTCCGGCCTTGGAAACGGCAA
TGGCTGAACTCTTTGCGTGTAGCACTTGATCTCCTTGAGCGGATGCTCGTGTTCGACCCGCGCAAGCGGATAAAC
GCGTCTGAGTCACTTGCTCATGCCTACGTCGCACCTTATCATGATCCTACCGACGAGCCGGAAGCGGAAGAGAAA
TTTGATTGGAGCTTCAATGACGCCGATCTTCCTATCGATACCTGGAAAGTCATGATGTACAGTGAAATCCTCGGT
AAGTCCTTTTGCTTCACAAGGCGATGCTTCTGTGTCAATATAGATTAACCGCCTTTTCTTAGACTTCCATCAGGT
CGATCAAGGGCAGGGGCTGGGCATCCCAGAAGGAGCGCTGGCTGGTCCAGAGGATGGGGGCTACTCGAATGGCCA
TGCTTGATCGCTGACATTTTCTCCCTGGATCTCTTCTTTGTCTCGGGTTATGTCTATTTCTTGATTTTTGTGAGT
TCCAAGGTTAGGACCCCGCGCCAACAACTTCAACATCCAATCAAGCTCGACGATACGTGTATTCTAATCGCCATT
GCCGTCTCTGTCTCTAAGCCACCTCATTTGTATTTTGTGTATATCTCTCCCTTGCCATGTTGTGCGCCTCTAGTA
CCATGTTTTACCCGGACTTACTTCCTCGTTCATCTGTCTCTGTTGTTTTTACTTCTCTGATACACGGTCGCTTTT
CCGGCGGCACATAGCCTTTGCTTGTTCCTTACCTCGGGGTTTCTTACGCCTTGGCTCGCGTACTTGTATATTCTT
CACTATTGGATCTGAAAATGTCAATTTAAATGGAACTTC
Length 2364