CopciAB_449440
Coprinopsis cinerea A43mutB43mut pab1-1 #326

General data

Systematic name CopciAB_449440 Strain Coprinopsis cinerea Okayama 7
Standard name HRR25 Synonyms 449440
Uniprot id Functional description Belongs to the protein kinase superfamily
Location scaffold_1:1331445..1334185 Strand +
Gene length (nt) 2741 Transcript length (nt) 2229
CDS length (nt) 1098 Protein length (aa) 365

Reciprocal best hits in model fungi

Strain name Gene / Protein name
Neurospora crassa ck-1a
Aspergillus nidulans AN4563_ckiA
Schizosaccharomyces pombe hhp1

Orthologs in mushroom models

Strain name Gene / Protein name Pident E-value Bits
Agrocybe aegerita Agrae_CAA7264740 93.7 1.603E-230 705
Hypsizygus marmoreus strain 51987-8 Hypma_RDB28600 93.3 5.284E-227 695
Pleurotus ostreatus PC15 PleosPC15_2_1111729 92.5 4.626E-225 689
Pleurotus ostreatus PC9 PleosPC9_1_112679 92.5 4.528E-225 689
Flammulina velutipes Flave_chr08AA00386 92.3 1.107E-224 688
Schizophyllum commune H4-8 Schco3_2172656 92.2 6.716E-224 686
Lentinula edodes B17 Lened_B_1_1_16260 90.7 1.04E-223 685
Lentinula edodes W1-26 v1.0 Lentinedodes1_342 90.7 1.305E-223 685
Grifola frondosa Grifr_OBZ78915 89.5 1.588E-220 676
Agaricus bisporus var bisporus (H97) Agabi_varbisH97_2_62578 95.4 4.11E-216 663
Agaricus bisporus var. burnettii JB137-S8 Agabi_varbur_1_31660 95.4 4.282E-216 663
Pleurotus eryngii ATCC 90797 Pleery1_1437732 95.4 3.317E-213 655
Ganoderma sp. 10597 SS1 v1.0 Gansp1_37853 93.6 3.629E-211 649
Lentinula edodes NBRC 111202 Lenedo1_1032047 93.7 3.954E-211 649
Auricularia subglabra Aurde3_1_1023935 89.1 1.035E-196 608

Expression

Name Summary Attribution Assay type
Carbon metabolism Transcriptional changes along alternative morphogenetic paths of C. cinerea Xie et al. 2020 RNA-Seq
Sample Mean cpm SD cpm Se of mean
sclerotia 308.3649 15.5044 8.9515
oidia 274.4417 21.4853 12.4046
vegetative_mycelium 257.4055 15.313 8.841
primordia 405.8551 17.4562 10.0784
hyphal_knot 300.9991 15.0372 8.6817
young_fruiting_body 906.0785 11.9243 6.8845
Complex carbon sources 1 (long incubation) Expression profiling on diverse complex carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Control - glucose 358.8997 45.7025 26.3863
Wheat bran 261.6431 60.4669 34.9106
Horse manure 392.8551 188.4487 108.8009
Oak leaves 690.9835 271.3099 156.6408
Hay 387.3275 71.99 41.5635
Corn stalk 437.1821 94.0701 54.3114
Pectine 336.8807 20.326 11.7352
Microcrystalline cellulose 304.2183 15.6395 9.0295
Xylose 449.6762 98.7804 57.0309
Cellobiose 353.2094 14.5206 8.3835
Lignin 346.8444 39.2717 22.6735
Apple peels 436.3869 34.5097 19.9242
Coprinopsis challenged with bacteria Transcriptional response to Bacillus subtilis and Escherichia coli. Kombrink et al. 2018 RNA-Seq
Sample Mean cpm SD cpm Se of mean
Control 231.3354 21.3572 12.3306
Bsubtilis 260.9167 20.7063 11.9548
Ecoli 209.8342 12.9722 7.4895
Early development 1 Time series expression profiling of basidiospore and oidium germination Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
BS 0h 72.6896 0.9547 0.5512
BS 4h 72.5764 7.4853 4.3217
BS 8h 136.6768 13.6772 7.8965
BS 12h 132.8734 27.4214 15.8318
Oidia 0 h 130.6562 32.7546 18.9109
Oidia 18 h 131.3061 13.3092 7.6841
Sclerotia 313.1592 5.9318 3.4247
Early development 2 Time series expression profiling of mycelial growth, light induction and fruiting body initiation. Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
DM 12h 287.1197 41.276 23.8307
DM 36h 234.6099 4.7517 2.7434
DM 60h 225.7271 7.9538 4.5921
DM 84h 260.7191 5.4078 3.1222
DM 108h 270.0689 24.116 13.9234
DM 132h 273.6887 35.9716 20.7682
DM 156hAE 350.1369 25.1303 14.509
ELI1hAE 314.4235 19.6643 11.3532
ELI2hAE 300.0464 11.5608 6.6746
LI2hAE 320.7182 57.0919 32.962
LI6hAE 357.555 36.0122 20.7917
LI12hAE 364.7356 32.7541 18.9106
LI18hAE 334.6922 43.5636 25.1514
LI 24hAE 407.7629 82.9104 47.8683
DM 156hAM 301.1444 17.2966 9.9862
ELI1hAM 331.4408 75.3941 43.5288
ELI2hAM 265.7069 25.6822 14.8276
LI2hAM 264.5662 16.5393 9.549
LI6hAM 334.8345 57.6257 33.2702
LI12hAM 333.0179 28.4128 16.4041
LI18hAM 333.8224 81.143 46.8479
LI 24hAM 413.6481 75.3017 43.4754
LI 24hHK 471.3182 105.9273 61.1572
L/D 6h 386.0743 102.1228 58.9606
L/D 12h 402.125 67.9274 39.2179
L/D 18h 290.744 40.5853 23.4319
L/D 24h 368.8432 28.8047 16.6304
Fruiting body development RNA-Seq analysis of fruiting body development Krizsan et al. 2019 RNA-Seq
Sample Mean cpm SD cpm Se of mean
Vegetative mycelium 196.0313 17.7424 10.2436
Hyphal knots 282.8967 24.0015 13.8573
Primordium 1 323.7607 3.2547 1.8791
Primordium 2 284.7013 62.6771 36.1866
Young Fruiting body cap 556.2683 147.6513 85.2465
Younf fruiting body gill 571.8673 58.3034 33.6615
Young fruiting body stipe 814.8625 164.7387 95.112
Mature fruiting body cap_gill 541.8713 216.3559 124.9131
Mature fruiting body stipe 847.6655 59.8175 34.5356
Nitrogen sources (12h incubation) Expression profiling on diverse nitrogen sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Complete medium - control 442.148 57.2398 33.0474
NH4NO3 292.6362 9.2396 5.3345
Proline 319.6648 25.087 14.484
Tryptophan 300.6417 21.2349 12.26
Isoleucin 312.7271 14.4374 8.3354
Arginine 296.4774 25.6627 14.8163
Metionine 339.1972 12.3635 7.138
NaNO3 277.8217 3.6009 2.079
Plant biomass (12h incubation) Expression profiling on diverse plant biomasses as carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose - control 442.148 57.2398 33.0474
Citrus peel 286.9554 12.6681 7.3139
Poplar leaves 472.3825 9.6626 5.5787
Typha leaves 382.7458 61.0579 35.2518
Overwintered Salix leaves 387.4814 34.1365 19.7087
Reed flowering 374.4171 31.5284 18.2029
Tigernut 398.2945 25.121 14.5036
Energy cane 410.3233 25.3256 14.6218
Guar gum 309.7077 80.4484 46.4469
Apple peels 313.947 45.3576 26.1872
Cellobiose 361.4867 15.2171 8.7856
Corn stalk 360.6684 46.2529 26.7041
Horse manure 370.109 20.8146 12.0173
Lignin 340.9688 100.2443 57.8761
Microcrystalline cellulose 363.2837 17.1115 9.8793
Oak leaves 334.4883 33.2913 19.2207
Pectin esterified 249.3917 27.5473 15.9045
Poplar sawdust 334.05 40.041 23.1177
Wheat bran 271.0505 34.6876 20.0269
Chlamydomonas reinhardtii 403.0745 49.8787 28.7975
Vertatryl alcohol 286.3371 18.917 10.9217
Furfural 203.7922 7.1491 4.1275
Autoclaved mycelium 407.8242 26.3813 15.2313
Simple and complex carbon and nitrogen sources Expression profiling on diverse complex carbon and nitrogen sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose control 253.3444 8.0266 4.6342
Ribose 332.9866 14.5933 8.4254
Mannose 334.0804 8.8254 6.2405
Fructose 308.9324 12.6389 7.297
Arabinose 330.4673 24.2998 14.0295
Xylose 310.9469 13.1065 7.567
Galacturonic acid 310.7482 32.519 18.7748
Rhamnogalacturonan 310.983 15.5808 8.9956
Pectin esterified 313.3817 10.5623 6.0981
Polygalacturonic acid 317.8872 20.2941 11.7168
Sodium acetate 344.164 7.41 4.2782
No nitrogen 299.0977 32.1927 18.5865
BSA 324.8884 21.0643 12.1615
Glutamine 310.4379 15.9975 9.2362
No phosphate 285.2624 10.8941 6.2897
No carbon 356.3804 12.5234 8.8554
No sulphur 292.91 29.8352 17.2253
Simple and complex carbon sources (12h incubation) Expression profiling on diverse complex carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose - control 442.148 57.2398 33.0474
Amylose 358.4647 9.8775 5.7028
Fucose 350.461 26.5716 15.3411
Galactose 375.4872 14.5154 8.3805
Lactose 334.6725 14.6388 8.4517
Maltose 365.9824 30.1139 17.3862
Mannitol 383.1487 32.5813 18.8108
Rhamnose 368.155 13.2501 7.65
Sorbitol 344.246 21.7314 12.5466
Trehalose 318.3509 55.7895 32.2101
Glycerol 378.0328 12.4924 7.2125
Glucuronic acid 367.3529 30.7787 17.7701
Arabinan 308.1331 42.2302 24.3816
Galactan 339.3346 7.802 4.5045
Galactomannan 378.5154 13.1837 7.6116
Glucan 356.9466 56.7129 32.7432
Xylan 359.0447 10.6406 6.1434
Xyloglucan 380.8462 11.1775 6.4534
Arabinogalactan 372.1269 44.5119 25.699
Pectin 387.2559 122.973 70.9985
Rhamnogalacturonan 485.5753 57.9944 33.4831
Polygalacturonic acid 340.8472 13.2771 7.6655
Mannan 355.9793 17.2924 9.9838
Amylopectin 277.183 28.1816 16.2706
Inulin 383.5634 5.7593 3.3251
BSA 428.7754 3.5028 2.0223
Starvation induced by water agar transfer Expression profiling on starvation induced by transfer to water agar Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Control 225.7271 7.9538 4.5921
2h WAT 339.9581 20.3271 11.7358
4h WAT 325.9453 88.36 51.0147
8h WAT 368.2286 69.5963 40.1814
16h WAT 342.7586 58.445 33.7432
24h WAT 329.7824 43.0859 24.8757
WAT hyphal knot -30h 327.7827 48.7505 28.1461
WAT hyphal knot -22h 319.0279 7.4329 4.2914
WAT hyphal knot -15h 318.1856 8.9432 5.1634
WAT hyphal knot -7.5h 337.4037 41.7389 24.098
WAT hyphal knot 322.0678 31.7031 18.3038
WAT hyphal knot +7.5h 341.6957 66.3962 38.3338
Straw time series Time series expression profiling on straw as a carbon source Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose control 261.9298 107.6811 62.1697
Straw 3h 274.7588 56.1016 32.3903
Straw 6h 217.7191 88.798 51.2675
Straw 12h 339.4033 7.8329 4.5223
Straw 24h 300.6486 33.7706 19.4975
Stress conditions 1 Expression profiling under various stress conditions Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Flask control 334.6518 93.9501 54.2421
Frost (-20C, 30min) 505.0626 60.9315 35.1788
Heat shock (47C, 2h) 1193.2253 96.4734 55.6989
High CO2 346.1752 36.0966 20.8404
Drought (4% agar, 12h) 384.7542 74.6333 43.0896
Oxidative (1mM H2O2, 3h) 338.4356 59.6547 34.4417
Acidic (pH4, 3h) 250.6259 31.1459 17.9821
Alkaline (pH9, 3h) 334.5174 18.067 10.431
Osmotic (sorbitol 2h) 228.9132 15.841 9.1458
CongoRed (3h) 417.6327 99.6045 57.5067
Cobalt chloride control 550.178 43.0779 24.871
Cobalt chloride 2mM 453.2256 84.6411 48.8676
Stress conditions 2 Expression profiling under various stress conditions Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Flask control 397.2119 286.7786 165.5717
Cold stimulation 308.7756 11.2145 6.4747
Scratched surface 512.7527 104.9459 60.5906
Ca2+, 200mM, 24h 172.3172 22.3225 12.8879
Cu2+, 2mM, 6h 196.9008 33.9546 19.6037
Voriconazole 263.8497 23.3608 13.4874
Trichoderma interaction, early 308.8201 19.6737 11.3586
Trichoderma interaction 60h 202.8625 33.7738 19.4993
Cobalt chloride 2mM repeat 238.402 23.8483 13.7688
Hypoxia 251.2259 24.372 14.0712
Hypoxia control 235.6065 10.0265 5.7888
Protoplastation control 369.2371 5.6599 4.0022
Protoplastation 3.5h 201.7649 26.6559 18.8486
Protoplastation 1.5h 258.4297 69.1992 48.9312

General data

Systematic name HRR25
Protein id CopciAB_449440.T0
Description Belongs to the protein kinase superfamily

Annotation summary

0 100 200 300 365

Conserved domains

Analysis Signature accession Signature description InterPro Accession Start End
CDD cd14125 STKc_CK1_delta_epsilon - 15 289
Pfam PF00069 Protein kinase domain IPR000719 16 234

SignalP

Prediction Start End Score
No records

Transmembrane domains

Domain n Start End Length
No records

InterPro

Accession Description
IPR000719 Protein kinase domain
IPR008271 Serine/threonine-protein kinase, active site
IPR017441 Protein kinase, ATP binding site
IPR011009 Protein kinase-like domain superfamily

GO

Go id Term Ontology
GO:0004672 protein kinase activity MF
GO:0005524 ATP binding MF
GO:0006468 protein phosphorylation BP

KEGG

KEGG Orthology
K14758

EggNOG

COG category Description
T Belongs to the protein kinase superfamily

CAZy

Class Family Subfamily
No records

Transcription factor

Group
No records

Conservation of CopciAB_449440 across fungi.

Arrow shows the origin of gene family containing CopciAB_449440.

Protein

Sequence id CopciAB_449440.T0
Sequence >CopciAB_449440.T0
MAESAHRLDLRVGGKYRLGKKIGSGSFGDIYLGINIISGEEVAIKLESVKAKHPQLEYESKVYKTLAGGVGVPFV
RWFGTECDYNAMVLDLLGPSLEDLFNFCNRKFSLKTVLLLADQLISRIEYIHSRNFIHRDIKPDNFLMGIGKRGN
QVNVIDFGLAKKFRDPKTHLHIPYRENKNLTGTARYTSINTHLGVEQARRDDLESLAYVLMYFLRGALPWQGLKA
ATKKQKYDRIMEKKMTTPTDLLCRGFPNEFGIFLNYTRALRFDDKPDYSYLRKLFRDLFVREGYQYDYVFDWSVQ
RGAQEDQAASSSKVPVGRRKVVQEADEDHRASDRMLRSHTRQAQQAGGSGMPQARAGRGRDAEVW
Length 365

Coding

Sequence id CopciAB_449440.T0
Sequence >CopciAB_449440.T0
ATGGCCGAATCTGCGCACAGACTGGATCTTAGAGTAGGCGGCAAATACAGACTTGGGAAAAAGATCGGTTCAGGG
TCATTTGGCGATATCTACCTTGGTATTAACATCATCTCTGGTGAAGAGGTCGCCATCAAGCTCGAATCAGTCAAG
GCCAAGCACCCCCAGCTCGAGTATGAGTCCAAGGTCTACAAGACCCTCGCCGGCGGTGTTGGCGTCCCCTTTGTG
AGGTGGTTTGGAACCGAGTGTGACTACAACGCCATGGTTCTCGACCTCCTCGGACCCTCTCTCGAGGATCTCTTC
AACTTCTGCAACCGCAAGTTCAGCCTCAAGACCGTTCTTCTCCTCGCTGATCAACTGATCTCTCGCATCGAGTAC
ATCCACTCTCGCAACTTCATCCACCGTGACATCAAGCCCGACAACTTCTTGATGGGCATCGGCAAACGTGGCAAC
CAGGTCAACGTCATTGACTTTGGTCTCGCGAAGAAATTCCGCGACCCAAAGACACATCTCCATATTCCTTACCGA
GAGAACAAGAATTTGACCGGTACCGCCCGCTACACTTCCATCAACACCCACTTGGGTGTCGAGCAAGCCCGTCGT
GACGACCTCGAATCCCTCGCCTATGTCCTCATGTACTTCCTCCGCGGCGCTCTGCCCTGGCAAGGCCTCAAGGCT
GCTACCAAGAAGCAGAAGTACGACCGTATCATGGAGAAGAAGATGACCACCCCCACCGACCTTCTCTGCCGTGGA
TTCCCCAACGAGTTTGGCATTTTCTTGAACTATACCCGTGCCCTTCGCTTCGATGACAAGCCCGACTATTCGTAC
CTTCGCAAGCTCTTCCGCGACCTCTTCGTTCGCGAAGGTTATCAGTACGATTACGTTTTCGACTGGAGTGTCCAG
CGTGGAGCTCAGGAGGACCAAGCTGCCTCCAGCTCGAAGGTTCCAGTCGGCCGTCGCAAGGTCGTTCAGGAGGCT
GACGAGGACCATCGTGCAAGCGACAGAATGCTTCGCTCCCACACCAGGCAGGCTCAGCAGGCCGGTGGATCCGGA
ATGCCTCAGGCCAGGGCTGGCCGGGGTCGTGATGCTGAAGTCTGGTAA
Length 1098

Transcript

Sequence id CopciAB_449440.T0
Sequence >CopciAB_449440.T0
ACTTTCTTCCAAACAACCATCTATCTATCCTCTTTATCCCTTTTATCTCTCTCTCCCTCAGTAATCGATGGCCGA
ATCTGCGCACAGACTGGATCTTAGAGTAGGCGGCAAATACAGACTTGGGAAAAAGATCGGTTCAGGGTCATTTGG
CGATATCTACCTTGGTATTAACATCATCTCTGGTGAAGAGGTCGCCATCAAGCTCGAATCAGTCAAGGCCAAGCA
CCCCCAGCTCGAGTATGAGTCCAAGGTCTACAAGACCCTCGCCGGCGGTGTTGGCGTCCCCTTTGTGAGGTGGTT
TGGAACCGAGTGTGACTACAACGCCATGGTTCTCGACCTCCTCGGACCCTCTCTCGAGGATCTCTTCAACTTCTG
CAACCGCAAGTTCAGCCTCAAGACCGTTCTTCTCCTCGCTGATCAACTGATCTCTCGCATCGAGTACATCCACTC
TCGCAACTTCATCCACCGTGACATCAAGCCCGACAACTTCTTGATGGGCATCGGCAAACGTGGCAACCAGGTCAA
CGTCATTGACTTTGGTCTCGCGAAGAAATTCCGCGACCCAAAGACACATCTCCATATTCCTTACCGAGAGAACAA
GAATTTGACCGGTACCGCCCGCTACACTTCCATCAACACCCACTTGGGTGTCGAGCAAGCCCGTCGTGACGACCT
CGAATCCCTCGCCTATGTCCTCATGTACTTCCTCCGCGGCGCTCTGCCCTGGCAAGGCCTCAAGGCTGCTACCAA
GAAGCAGAAGTACGACCGTATCATGGAGAAGAAGATGACCACCCCCACCGACCTTCTCTGCCGTGGATTCCCCAA
CGAGTTTGGCATTTTCTTGAACTATACCCGTGCCCTTCGCTTCGATGACAAGCCCGACTATTCGTACCTTCGCAA
GCTCTTCCGCGACCTCTTCGTTCGCGAAGGTTATCAGTACGATTACGTTTTCGACTGGAGTGTCCAGCGTGGAGC
TCAGGAGGACCAAGCTGCCTCCAGCTCGAAGGTTCCAGTCGGCCGTCGCAAGGTCGTTCAGGAGGCTGACGAGGA
CCATCGTGCAAGCGACAGAATGCTTCGCTCCCACACCAGGCAGGCTCAGCAGGCCGGTGGATCCGGAATGCCTCA
GGCCAGGGCTGGCCGGGGTCGTGATGCTGAAGTCTGGTAAACGGGCTTCTTAGTTTGGTTTCTGGCCTGTTTTCT
CTATAGTGCGTCCCGAGAGTGTCGAGCGAATGGGGGGTGGAGGGCAGAAGCAGGTATCGCTCGGCAGTGACTGAT
GATCAAGGACGTCGTATGGTTGGGTGGAGACGCGTCCCTGGGATCGTCAGGAGTATGTGGATGCGCGGAGGAGGT
TGTAGAAGTTACGCGAGTGTTGGCGGGGGTTGTTGGATGGTTTCGTTTGGGCGTTTCCCCCAACTTGTTGCATAG
ATCTGGGTTCACGGACAGCATCAGTTGACGCCCGGCGATTCCACCCCTATCATACCAAGTATTCCCTTCAAGAAG
AAGCCTGGACAACCTCTCAACTCAATCGCAAGCTTCCCATGCCCAAGGTGTATTCGACCCTAAACATTATTCTGG
CTTCATTGCCTGTTTACATCGCTTCTTTCATCTGAAACGGACGCTTTTTCTTTTCACGTCAGTCTCTTGTTCTTC
GGAACAAGGGCTGGCCGCCTCACCCCCAACCCCTTGTTATCTATTATCATAATCCAAATCCTCACCCCCTGCGCC
CTTTCAGCCTAACGTTAGCCCATTTCCCCCTTGTACACCTTCCCGTTCACTTGACCTGGTTTCCCTTTTTTTCAT
CGGTAGTACACGATCCCCCATCACTCGTATTATTGACATTCATTGGCTTCAAGAATTTCCCCTTCCCCCACCATT
CCTTTCTTCCCCCTTTCTGTTTCTGTATGGGTTTTAGGTCTTCACTTTATCCTTCCGTCCTCCACCTTTCTCTTC
CCCAATGAGAAAGGGCGAGCGGGACGGAAGAGGGCGCCGAGTGTAGAAGGAGAGGTTACGTCGAGTGCTGGACTC
GCGTGAGGAGAGTTGACGAACAGTTGTCGGTGTGGACAATAACAAGTTTCGTAGTAGACATGCGTCGTATGATCA
CCCCTCGTTTCCACCCCTTTCGGTCTCTCCGAATCCCTCACCCCCTTCCGAATCGATGTCTACTGTTGCCTTCAA
TGTATGACTATTGTGACGAATGTTGTTAATATGACCAGACACTTGTGTTCCGCG
Length 2229

Gene

Sequence id CopciAB_449440.T0
Sequence >CopciAB_449440.T0
ACTTTCTTCCAAACAACCATCTATCTATCCTCTTTATCCCTTTTATCTGTGAGTAGCCCTCTTTTTCTTTTCGTC
CCCTCGTCGTCGTCGTCGCCCAGCGGGTGCCACACAGCGCCTGCCCTGCAACCGCACAGCTGTCCCATTCAGCCA
TTGTACCCTTCCTCCTTTTCTCGCCCCGCCCGTCCTTGTTCCCAGAACAATGAGGACTCGGTCAAGCGACAACGA
CAGGCGTCACCCCTGGTTAGCCACCGCAACGAGGCCGGCCTGTTGTCTGGGATCCACATGCCCCCAGCCCTGTTA
TATATAAAGCCCATCATGCACTCCTTCAATTTTTTGCCTTCCTTCCCCCACTTTCTCTCTTCACCCTTACTTACA
CCGGTCTCTAGCTCTCTCCCTCAGTAATCGATGGCCGAATCTGCGCACAGACTGGATCTTAGAGTAGGCGGCAAA
TACAGACTTGGGAAAAAGATCGGTTCAGGGTCATTTGGTGCGTCGTCTCCGTCCGCAGGCGTCATGAATGATGTT
ACTCACACTTGCATGCAGGCGATATCTACCTTGGTATTAACATCATCTCTGGTGAAGAGGTCGCCATCAAGCTCG
AATCAGTCAAGGCCAAGCACCCCCAGCTCGAGTATGAGTCCAAGGTCTACAAGACCCTCGCCGGCGGTGTTGGCG
TCCCCTTTGTGAGGTGGTTTGGAACCGAGTGTGACTACAACGCCATGGTTCTCGACCTCCTCGGACCCTCTCTCG
AGGATCTCTTCAACTTCTGCAACCGCAAGTTCAGCCTCAAGACCGTTCTTCTCCTCGCTGATCAACTGGTGAGTC
CGGGTCTCCCCCCTATATCCTTTTCATGCTCCGTTTGCTGATGTGGCATGCAGATCTCTCGCATCGAGTACATCC
ACTCTCGCAACTTCATCCACCGTGACATCAAGCCCGACAACTTCTTGATGGGCATCGGCAAACGTGGCAACCAGG
TCAACGTCATTGACTTTGGTCTCGCGAAGAAATTCCGCGACCCAAAGACACATCTCCATATTCCTTACCGAGAGA
ACAAGAATTTGACCGGTACCGCCCGCTACACTTCCATCAACACCCACTTGGGTGTCGAGCAAGCCCGTCGTGACG
ACCTCGAATCCCTCGCCTATGTCCTCATGTACTTCCTCCGCGGCGCTCTGCCCTGGCAAGGCCTCAAGGCTGCTA
CCAAGAAGCAGAAGTACGACCGTATCATGGAGAAGAAGATGACCACCCCCACCGACCTTCTCTGCCGTGGATTCC
CCAACGAGTTTGGCATTTTCTTGAACTATACCCGTGCCCTTCGCTTCGATGACAAGCCCGACTATTCGTACCTTC
GCAAGCTCTTCCGCGACCTCTTCGTTCGCGAAGGTTATCAGTACGATTACGTTTTCGACTGGAGTGTCCAGCGTG
GAGCTCAGGAGGACCAAGCTGCCTCCAGCTCGAAGGTTCCAGTCGGCCGTCGCAAGGTCGTTCAGGAGGCTGACG
AGGACCATCGTGCAAGCGACAGAATGTAAGCATGACTTTACCCTTACTCCAGTCACCCAGATCGCGCTAACAATT
GTGAATAGGCTTCGCTCCCACACCAGGCAGGCTCAGCAGGCCGGTGGATCCGGAATGCCTCAGGCCAGGGCTGGC
CGGGGTCGTGATGCTGAAGTCTGGTAAACGGGCTTCTTAGTTTGGTTTCTGGCCTGTTTTCTCTATAGTGCGTCC
CGAGAGTGTCGAGCGAATGGGGGGTGGAGGGCAGAAGCAGGTATCGCTCGGCAGTGACTGATGATCAAGGACGTC
GTATGGTTGGGTGGAGACGCGTCCCTGGGATCGTCAGGAGTATGTGGATGCGCGGAGGAGGTTGTAGAAGTTACG
CGAGTGTTGGCGGGGGTTGTTGGATGGTTTCGTTTGGGCGTTTCCCCCAACTTGTTGCATAGATCTGGGTTCACG
GACAGCATCAGTTGACGCCCGGCGATTCCACCCCTATCATACCAAGTATTCCCTTCAAGAAGAAGCCTGGACAAC
CTCTCAACTCAATCGCAAGCTTCCCATGCCCAAGGTGTATTCGACCCTAAACATTATTCTGGCTTCATTGCCTGT
TTACATCGCTTCTTTCATCTGAAACGGACGCTTTTTCTTTTCACGTCAGTCTCTTGTTCTTCGGAACAAGGGCTG
GCCGCCTCACCCCCAACCCCTTGTTATCTATTATCATAATCCAAATCCTCACCCCCTGCGCCCTTTCAGCCTAAC
GTTAGCCCATTTCCCCCTTGTACACCTTCCCGTTCACTTGACCTGGTTTCCCTTTTTTTCATCGGTAGTACACGA
TCCCCCATCACTCGTATTATTGACATTCATTGGCTTCAAGAATTTCCCCTTCCCCCACCATTCCTTTCTTCCCCC
TTTCTGTTTCTGTATGGGTTTTAGGTCTTCACTTTATCCTTCCGTCCTCCACCTTTCTCTTCCCCAATGAGAAAG
GGCGAGCGGGACGGAAGAGGGCGCCGAGTGTAGAAGGAGAGGTTACGTCGAGTGCTGGACTCGCGTGAGGAGAGT
TGACGAACAGTTGTCGGTGTGGACAATAACAAGTTTCGTAGTAGACATGCGTCGTATGATCACCCCTCGTTTCCA
CCCCTTTCGGTCTCTCCGAATCCCTCACCCCCTTCCGAATCGATGTCTACTGTTGCCTTCAATGTATGACTATTG
TGACGAATGTTGTTAATATGACCAGACACTTGTGTTCCGCG
Length 2741