CopciAB_467792
Coprinopsis cinerea A43mutB43mut pab1-1 #326

General data

Systematic name CopciAB_467792 Strain Coprinopsis cinerea Okayama 7
Standard name CBK1 Synonyms 467792
Uniprot id Functional description Haspin like kinase domain
Location scaffold_5:1722839..1725052 Strand +
Gene length (nt) 2214 Transcript length (nt) 1735
CDS length (nt) 1512 Protein length (aa) 503

Reciprocal best hits in model fungi

Strain name Gene / Protein name
Aspergillus nidulans AN5529_cotA
Candida albicans CBK1
Saccharomyces cerevisiae YNL161W_CBK1
Schizosaccharomyces pombe orb6

Orthologs in mushroom models

Strain name Gene / Protein name Pident E-value Bits
Lentinula edodes B17 Lened_B_1_1_10145 76.8 4.378E-259 795
Lentinula edodes NBRC 111202 Lenedo1_1140630 76.8 5.533E-259 795
Lentinula edodes W1-26 v1.0 Lentinedodes1_14213 76.8 5.49E-259 795
Hypsizygus marmoreus strain 51987-8 Hypma_RDB22790 78.1 3.207E-258 793
Agrocybe aegerita Agrae_CAA7259768 79.2 6.322E-258 792
Flammulina velutipes Flave_chr11AA00694 79.3 2.315E-250 770
Pleurotus ostreatus PC15 PleosPC15_2_1064218 79 2.806E-247 761
Pleurotus ostreatus PC9 PleosPC9_1_83344 78.8 6.094E-247 760
Ganoderma sp. 10597 SS1 v1.0 Gansp1_41520 75.8 1.48E-246 759
Pleurotus eryngii ATCC 90797 Pleery1_1167579 77.8 2.121E-243 750
Auricularia subglabra Aurde3_1_1204651 73.9 3.725E-242 747
Grifola frondosa Grifr_OBZ70445 72.7 1.766E-235 727
Schizophyllum commune H4-8 Schco3_2500728 73.3 7.538E-230 711

Expression

Name Summary Attribution Assay type
Carbon metabolism Transcriptional changes along alternative morphogenetic paths of C. cinerea Xie et al. 2020 RNA-Seq
Sample Mean cpm SD cpm Se of mean
sclerotia 29.0261 1.7494 1.01
oidia 54.7228 6.6153 3.8193
vegetative_mycelium 49.8123 5.2695 3.0423
primordia 25.8128 0.8314 0.48
hyphal_knot 35.1776 6.0276 3.48
young_fruiting_body 10.5443 1.2162 0.7022
Complex carbon sources 1 (long incubation) Expression profiling on diverse complex carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Control - glucose 71.0606 18.0844 10.441
Wheat bran 65.9454 7.0732 4.0837
Horse manure 61.3972 5.2271 3.0179
Oak leaves 40.5323 11.8006 6.8131
Hay 56.7718 2.6327 1.52
Corn stalk 56.4213 4.7142 2.7217
Pectine 49.3004 3.655 2.1102
Microcrystalline cellulose 48.9552 5.007 2.8908
Xylose 76.1328 8.6092 4.9705
Cellobiose 104.8588 20.4078 11.7824
Lignin 57.2699 21.7006 12.5288
Apple peels 59.9105 3.9961 2.3071
Coprinopsis challenged with bacteria Transcriptional response to Bacillus subtilis and Escherichia coli. Kombrink et al. 2018 RNA-Seq
Sample Mean cpm SD cpm Se of mean
Control 78.5059 8.213 4.7418
Bsubtilis 54.268 2.2436 1.2954
Ecoli 57.0525 5.3271 3.0756
Early development 1 Time series expression profiling of basidiospore and oidium germination Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
BS 0h 3.6494 1.0641 0.6144
BS 4h 15.587 3.0605 1.767
BS 8h 15.4884 1.775 1.0248
BS 12h 17.5012 2.4968 1.4415
Oidia 0 h 7.014 1.9362 1.1179
Oidia 18 h 21.7166 4.3882 2.5335
Sclerotia 17.8733 6.2801 3.6258
Early development 2 Time series expression profiling of mycelial growth, light induction and fruiting body initiation. Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
DM 12h 18.4198 4.237 2.4462
DM 36h 21.205 3.1162 1.7991
DM 60h 18.5464 3.8394 2.2167
DM 84h 16.4964 1.4341 0.828
DM 108h 15.6162 1.5225 0.879
DM 132h 15.3626 1.719 0.9925
DM 156hAE 18.1176 1.5042 0.8685
ELI1hAE 15.7187 3.3966 1.961
ELI2hAE 19.6101 2.9055 1.6775
LI2hAE 15.4207 0.9641 0.5566
LI6hAE 13.3764 0.6539 0.3775
LI12hAE 16.5355 1.0632 0.6138
LI18hAE 14.1935 2.8104 1.6226
LI 24hAE 20.1577 1.0225 0.5903
DM 156hAM 20.9091 0.6896 0.3982
ELI1hAM 21.4373 5.4712 3.1588
ELI2hAM 18.5917 1.7172 0.9914
LI2hAM 25.1305 4.8736 2.8138
LI6hAM 24.3295 2.3187 1.3387
LI12hAM 16.9219 3.4052 1.966
LI18hAM 13.2961 1.2652 0.7305
LI 24hAM 18.5038 2.0289 1.1714
LI 24hHK 25.7664 1.1927 0.6886
L/D 6h 22.7968 2.7973 1.615
L/D 12h 16.8699 3.6206 2.0904
L/D 18h 20.079 4.4656 2.5782
L/D 24h 17.0814 0.8577 0.4952
Fruiting body development RNA-Seq analysis of fruiting body development Krizsan et al. 2019 RNA-Seq
Sample Mean cpm SD cpm Se of mean
Vegetative mycelium 26.4773 1.8182 1.0497
Hyphal knots 29.1724 6.3081 3.642
Primordium 1 33.4431 1.0069 0.5813
Primordium 2 33.9289 2.8522 1.6467
Young Fruiting body cap 33.7702 3.5912 2.0734
Younf fruiting body gill 22.0251 10.8762 6.2794
Young fruiting body stipe 18.4395 1.8461 1.0659
Mature fruiting body cap_gill 33.052 4.1968 2.423
Mature fruiting body stipe 29.1523 5.9824 3.454
Nitrogen sources (12h incubation) Expression profiling on diverse nitrogen sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Complete medium - control 29.2448 2.4332 1.4048
NH4NO3 39.0398 2.9066 1.6781
Proline 33.1373 8.2277 4.7503
Tryptophan 31.1521 2.8471 1.6438
Isoleucin 33.0938 6.2262 3.5947
Arginine 35.5682 3.087 1.7823
Metionine 25.2055 1.0682 0.6167
NaNO3 26.738 1.0447 0.6032
Plant biomass (12h incubation) Expression profiling on diverse plant biomasses as carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose - control 29.2448 2.4332 1.4048
Citrus peel 15.0465 1.6766 0.968
Poplar leaves 31.8473 2.3488 1.3561
Typha leaves 26.921 4.0508 2.3387
Overwintered Salix leaves 25.1703 4.7481 2.7413
Reed flowering 22.7625 7.7771 4.4901
Tigernut 25.6219 3.0179 1.7424
Energy cane 24.256 3.7483 2.1641
Guar gum 33.2778 12.5361 7.2377
Apple peels 39.7829 4.812 2.7782
Cellobiose 41.7764 2.1953 1.2675
Corn stalk 43.0215 4.7062 2.7171
Horse manure 34.698 2.8822 1.6641
Lignin 26.1566 10.3133 5.9544
Microcrystalline cellulose 36.2711 7.8641 4.5404
Oak leaves 39.1136 7.3284 4.2311
Pectin esterified 38.9331 3.035 1.7522
Poplar sawdust 39.5541 6.405 3.6979
Wheat bran 43.7786 1.9653 1.1347
Chlamydomonas reinhardtii 29.7222 0.5287 0.3052
Vertatryl alcohol 29.5496 7.7695 4.4857
Furfural 25.5969 7.6496 4.4165
Autoclaved mycelium 32.3723 0.7184 0.4148
Simple and complex carbon and nitrogen sources Expression profiling on diverse complex carbon and nitrogen sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose control 66.8508 5.7113 3.2974
Ribose 77.5516 6.8586 3.9598
Mannose 76.1717 12.6972 8.9783
Fructose 65.0904 7.8068 4.5073
Arabinose 69.0386 13.4921 7.7896
Xylose 72.0744 6.4333 3.7142
Galacturonic acid 67.9021 6.1263 3.537
Rhamnogalacturonan 69.2902 5.3885 3.1111
Pectin esterified 65.4015 10.4659 6.0425
Polygalacturonic acid 65.1196 0.8184 0.4725
Sodium acetate 77.2592 6.3175 3.6474
No nitrogen 61.302 4.1117 2.3739
BSA 65.943 6.026 3.4791
Glutamine 62.7812 8.5034 4.9095
No phosphate 77.3754 4.5745 2.6411
No carbon 80.7106 0.7882 0.5574
No sulphur 96.1507 1.3963 0.8062
Simple and complex carbon sources (12h incubation) Expression profiling on diverse complex carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose - control 29.2448 2.4332 1.4048
Amylose 33.1267 4.4376 2.562
Fucose 34.4328 0.6485 0.3744
Galactose 28.63 2.4333 1.4049
Lactose 35.6873 1.4663 0.8466
Maltose 31.0305 0.6697 0.3866
Mannitol 31.9694 4.7757 2.7572
Rhamnose 29.5847 2.9853 1.7236
Sorbitol 33.7438 2.1115 1.2191
Trehalose 27.4585 1.9524 1.1272
Glycerol 24.6782 4.8668 2.8098
Glucuronic acid 35.991 7.364 4.2516
Arabinan 36.9124 8.7719 5.0644
Galactan 29.6971 0.5229 0.3019
Galactomannan 42.2677 18.8272 10.8699
Glucan 29.7911 5.7878 3.3416
Xylan 37.6981 3.0287 1.7486
Xyloglucan 43.2244 2.7096 1.5644
Arabinogalactan 44.7012 1.819 1.0502
Pectin 22.9706 6.1121 3.5288
Rhamnogalacturonan 20.4699 0.6394 0.3691
Polygalacturonic acid 31.9785 12.1984 7.0428
Mannan 29.5142 3.7681 2.1755
Amylopectin 24.0607 1.0681 0.6166
Inulin 29.8224 4.8327 2.7902
BSA 23.2248 2.3318 1.3463
Starvation induced by water agar transfer Expression profiling on starvation induced by transfer to water agar Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Control 18.5464 3.8394 2.2167
2h WAT 14.1737 3.0554 1.764
4h WAT 13.6302 2.6945 1.5556
8h WAT 14.8965 3.0355 1.7526
16h WAT 15.2203 2.2507 1.2994
24h WAT 14.4078 3.1618 1.8255
WAT hyphal knot -30h 16.2581 4.3499 2.5114
WAT hyphal knot -22h 16.718 2.746 1.5854
WAT hyphal knot -15h 17.4028 3.0886 1.7832
WAT hyphal knot -7.5h 16.1835 1.9293 1.1139
WAT hyphal knot 19.1116 0.9118 0.5264
WAT hyphal knot +7.5h 16.0933 2.247 1.2973
Straw time series Time series expression profiling on straw as a carbon source Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose control 25.3785 3.4395 1.9858
Straw 3h 32.8503 5.6581 3.2667
Straw 6h 29.2845 1.7804 1.0279
Straw 12h 28.8647 0.8296 0.479
Straw 24h 26.8179 4.3529 2.5131
Stress conditions 1 Expression profiling under various stress conditions Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Flask control 11.038 3.9716 2.293
Frost (-20C, 30min) 18.3923 3.2065 1.8513
Heat shock (47C, 2h) 8.2459 2.9397 1.6973
High CO2 14.0452 1.9016 1.0979
Drought (4% agar, 12h) 23.501 1.9275 1.1128
Oxidative (1mM H2O2, 3h) 12.6346 0.82 0.4734
Acidic (pH4, 3h) 12.4789 1.416 0.8175
Alkaline (pH9, 3h) 16.0581 1.9241 1.1109
Osmotic (sorbitol 2h) 12.6748 1.0866 0.6274
CongoRed (3h) 15.1398 3.6231 2.0918
Cobalt chloride control 13.0917 0.7061 0.4077
Cobalt chloride 2mM 14.2795 2.9317 1.6926
Stress conditions 2 Expression profiling under various stress conditions Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Flask control 14.5561 4.902 2.8302
Cold stimulation 15.9567 1.3505 0.7797
Scratched surface 25.1963 2.5025 1.4448
Ca2+, 200mM, 24h 31.2216 3.3617 1.9409
Cu2+, 2mM, 6h 12.7098 6.1385 3.544
Voriconazole 12.5459 0.4425 0.2555
Trichoderma interaction, early 19.3113 1.3621 0.7864
Trichoderma interaction 60h 5.221 7.6895 4.4395
Cobalt chloride 2mM repeat 15.4091 7.4375 4.2941
Hypoxia 13.2822 3.4733 2.0053
Hypoxia control 11.6969 0.889 0.5133
Protoplastation control 12.7277 0.1727 0.1221
Protoplastation 3.5h 11.2669 1.6774 1.1861
Protoplastation 1.5h 11.6517 3.9239 2.7746

General data

Systematic name CBK1
Protein id CopciAB_467792.T0
Description Haspin like kinase domain

Annotation summary

0 100 200 300 400 500 503

Conserved domains

Analysis Signature accession Signature description InterPro Accession Start End
CDD cd21773 MobB_CBK1 - 46 127
Pfam PF00069 Protein kinase domain IPR000719 132 284
Pfam PF00069 Protein kinase domain IPR000719 329 435

SignalP

Prediction Start End Score
No records

Transmembrane domains

Domain n Start End Length
No records

InterPro

Accession Description
IPR017441 Protein kinase, ATP binding site
IPR000961 AGC-kinase, C-terminal
IPR000719 Protein kinase domain
IPR011009 Protein kinase-like domain superfamily
IPR008271 Serine/threonine-protein kinase, active site

GO

Go id Term Ontology
GO:0005524 ATP binding MF
GO:0004674 protein serine/threonine kinase activity MF
GO:0006468 protein phosphorylation BP
GO:0004672 protein kinase activity MF

KEGG

KEGG Orthology
K08286

EggNOG

COG category Description
T Haspin like kinase domain

CAZy

Class Family Subfamily
No records

Transcription factor

Group
No records

Conservation of CopciAB_467792 across fungi.

Arrow shows the origin of gene family containing CopciAB_467792.

Protein

Sequence id CopciAB_467792.T0
Sequence >CopciAB_467792.T0
MQGLNTQNIRKTSSRVNINQSRQPSGPSPAATAQGAAKSPDYVYFDRNPSTCFSEESQIRAKSAQLKLENYYKVA
VESAVERNARRVELERRLQEDTLISDSRKNRQLQQLGKKESTFLRLRRTKIGLNDFRTVKVIGKGAFGEVRLVQK
TDTGKIYAMKLLRKNEMLKKDQLAHVRAERDVLAESDSPWVVSLFYSFQDPTYLYLVMEFLPGGDLMTMLIKYDT
FSEDVTRFYMAECVLAIEAVHRMGFIHRDIKPDNILIDKDGHIKLSDFGLSTGFHKQHDSSYYQRLLESAKNSSN
NTPQSSRNSVMVNSINLTISNQDIATWKANRRKLAYSTVGTPDYIAPEIFLQKGYGKECDWWSLGAIMFECLVGY
PPFCSESTHETYQKIIHWRHCLSFPSDIHLSAEALDLIQRMITSADQRLNVDQIKRHPFFYGVDWATIRQIDAPF
VPRLSSITDTSYFPTDEIDQVTDDIPQDASSADKDLAFLGYTFKRFSISSHAF
Length 503

Coding

Sequence id CopciAB_467792.T0
Sequence >CopciAB_467792.T0
ATGCAGGGGCTGAACACCCAAAACATCCGCAAGACCTCGTCCAGAGTCAACATAAACCAATCCCGGCAGCCCTCT
GGTCCCAGTCCTGCGGCAACAGCACAAGGAGCCGCCAAATCACCGGATTACGTGTATTTTGACAGAAATCCTTCA
ACATGCTTCTCTGAAGAATCGCAGATAAGAGCCAAGAGCGCCCAACTGAAGCTGGAGAACTACTACAAAGTAGCG
GTCGAATCGGCAGTCGAACGAAATGCACGACGTGTAGAACTTGAACGCAGGCTCCAAGAGGACACCCTAATCTCT
GATTCAAGAAAGAATCGGCAGTTACAACAGCTTGGCAAGAAGGAATCCACGTTCCTGCGACTTAGGAGGACCAAA
ATTGGCTTGAATGACTTTAGGACTGTCAAGGTCATCGGGAAGGGAGCTTTTGGAGAGGTACGGTTAGTCCAGAAG
ACGGATACAGGGAAGATATATGCCATGAAGCTGTTGAGGAAGAATGAAATGTTGAAGAAGGATCAGCTCGCACAC
GTCCGCGCTGAGCGCGATGTACTTGCCGAATCCGACTCTCCATGGGTGGTCTCGCTCTTCTATTCCTTCCAGGAC
CCGACGTATCTATACCTGGTCATGGAATTCCTGCCGGGCGGGGATCTGATGACCATGCTAATCAAGTACGACACG
TTCTCCGAGGATGTTACGCGATTCTACATGGCAGAGTGCGTTCTCGCCATTGAAGCTGTCCATCGAATGGGATTC
ATCCATCGAGACATCAAACCGGATAACATTCTGATCGACAAAGACGGACATATCAAGCTGAGCGACTTTGGTCTT
TCCACTGGTTTCCACAAGCAGCATGATTCGAGTTATTACCAACGCTTGTTAGAATCGGCCAAAAACTCGTCGAAT
AATACACCTCAGTCGTCGAGGAACAGCGTCATGGTAAATTCCATCAACCTCACTATCAGTAATCAAGATATTGCA
ACATGGAAAGCTAATCGACGGAAACTTGCCTACTCCACTGTCGGTACTCCCGATTACATCGCTCCAGAAATCTTC
CTCCAAAAGGGATATGGAAAGGAGTGTGACTGGTGGTCACTGGGTGCTATCATGTTCGAGTGTTTGGTGGGATAC
CCTCCATTCTGCTCCGAATCCACCCACGAGACATATCAGAAGATCATTCATTGGCGCCATTGCCTTTCTTTCCCG
AGCGATATTCATCTGAGCGCGGAGGCATTGGATCTAATACAAAGGATGATCACCTCTGCTGACCAGAGGCTAAAT
GTGGACCAAATCAAGCGACATCCATTCTTCTATGGTGTGGACTGGGCTACCATTCGACAGATAGACGCGCCGTTC
GTTCCTCGGCTAAGCTCGATCACCGACACATCATATTTCCCAACGGACGAAATCGACCAAGTCACGGACGATATT
CCCCAGGATGCTTCGTCCGCGGACAAGGATCTTGCATTTCTTGGATACACCTTCAAAAGGTTTTCAATATCTTCG
CATGCATTCTAA
Length 1512

Transcript

Sequence id CopciAB_467792.T0
Sequence >CopciAB_467792.T0
AGAACGGTTCTCTCATTCCACTAGCTTTCCAATCCAACCCGCTCACATATATCCTCCGTTTTTTTGACCTCTTAC
CACGCACACACAATATGCAGGGGCTGAACACCCAAAACATCCGCAAGACCTCGTCCAGAGTCAACATAAACCAAT
CCCGGCAGCCCTCTGGTCCCAGTCCTGCGGCAACAGCACAAGGAGCCGCCAAATCACCGGATTACGTGTATTTTG
ACAGAAATCCTTCAACATGCTTCTCTGAAGAATCGCAGATAAGAGCCAAGAGCGCCCAACTGAAGCTGGAGAACT
ACTACAAAGTAGCGGTCGAATCGGCAGTCGAACGAAATGCACGACGTGTAGAACTTGAACGCAGGCTCCAAGAGG
ACACCCTAATCTCTGATTCAAGAAAGAATCGGCAGTTACAACAGCTTGGCAAGAAGGAATCCACGTTCCTGCGAC
TTAGGAGGACCAAAATTGGCTTGAATGACTTTAGGACTGTCAAGGTCATCGGGAAGGGAGCTTTTGGAGAGGTAC
GGTTAGTCCAGAAGACGGATACAGGGAAGATATATGCCATGAAGCTGTTGAGGAAGAATGAAATGTTGAAGAAGG
ATCAGCTCGCACACGTCCGCGCTGAGCGCGATGTACTTGCCGAATCCGACTCTCCATGGGTGGTCTCGCTCTTCT
ATTCCTTCCAGGACCCGACGTATCTATACCTGGTCATGGAATTCCTGCCGGGCGGGGATCTGATGACCATGCTAA
TCAAGTACGACACGTTCTCCGAGGATGTTACGCGATTCTACATGGCAGAGTGCGTTCTCGCCATTGAAGCTGTCC
ATCGAATGGGATTCATCCATCGAGACATCAAACCGGATAACATTCTGATCGACAAAGACGGACATATCAAGCTGA
GCGACTTTGGTCTTTCCACTGGTTTCCACAAGCAGCATGATTCGAGTTATTACCAACGCTTGTTAGAATCGGCCA
AAAACTCGTCGAATAATACACCTCAGTCGTCGAGGAACAGCGTCATGGTAAATTCCATCAACCTCACTATCAGTA
ATCAAGATATTGCAACATGGAAAGCTAATCGACGGAAACTTGCCTACTCCACTGTCGGTACTCCCGATTACATCG
CTCCAGAAATCTTCCTCCAAAAGGGATATGGAAAGGAGTGTGACTGGTGGTCACTGGGTGCTATCATGTTCGAGT
GTTTGGTGGGATACCCTCCATTCTGCTCCGAATCCACCCACGAGACATATCAGAAGATCATTCATTGGCGCCATT
GCCTTTCTTTCCCGAGCGATATTCATCTGAGCGCGGAGGCATTGGATCTAATACAAAGGATGATCACCTCTGCTG
ACCAGAGGCTAAATGTGGACCAAATCAAGCGACATCCATTCTTCTATGGTGTGGACTGGGCTACCATTCGACAGA
TAGACGCGCCGTTCGTTCCTCGGCTAAGCTCGATCACCGACACATCATATTTCCCAACGGACGAAATCGACCAAG
TCACGGACGATATTCCCCAGGATGCTTCGTCCGCGGACAAGGATCTTGCATTTCTTGGATACACCTTCAAAAGGT
TTTCAATATCTTCGCATGCATTCTAAGGTTGCTCCTGCCATTTTCTGCTGGTTCAGACGCCCTGCATGGGGTGAG
ACAATGTTCTAACAATAGATCGCACGTTTATAAGTAGCAGGAATGTATGGCCACAAGATGATAATCTATTTCAGT
TGTAACAGCC
Length 1735

Gene

Sequence id CopciAB_467792.T0
Sequence >CopciAB_467792.T0
AGAACGGTTCTCTCATTCCACTAGCTTTCCAATCCAACCCGCTCACATATATCCTCCGTTTTTTTGACCTCTTAC
CACGCACACACAATATGCAGGGGCTGAACACCCAAAACATCCGCAAGACCTCGTCCAGAGTCAACATAAACCAAT
CCCGGCAGCCCTCTGGTCCCAGTCCTGCGGCAACAGCACAAGGAGCCGCCAAATCACCGGATTGTGAGTTTCGCA
CCAACAATCGTACTGAAACGCCACTCTGAACAGCCCCCTTCAGACGTGTATTTTGACAGAAATCCTTCAACATGC
TTCTCTGAAGAATCGCAGATAAGAGCCAAGAGCGCCCAACTGAAGCTGGAGAACTACTACAAAGTAGCGGTCGAA
TCGGCAGTCGAACGAAATGCACGGTGCGTGCTGGGGTTCCTTTCGCATTGAAGAACTGACCCCTGATTGAAATCT
TCTCCCTAGACGTGTAGAACTTGAACGCAGGCTCCAAGAGGACACCCTAATCTCTGATTCAAGAAAGAATCGGCA
GTTACAACAGCTTGGCAAGAAGGAATCCACGTTCCTGCGACTTAGGAGGACCAAAATTGGCTTGAATGACTTTAG
GACTGTCAAGGTCATCGGGAAGGGAGCTTTTGGAGAGGTATGTAGCGCACATCCTGCATTGAATTGAATTGCGTG
CTCAGGTACTACCAGGTACGGTTAGTCCAGAAGACGGATACAGGGAAGATATATGCCATGAAGCTGTTGAGGAAG
AATGAAATGTTGAAGAAGGATCAGGTTGGTACAGAAACTTTCTCTACCTCAGGAGGTGGCTCATTGTTGTTATTA
GCTCGCACACGTCCGCGCTGAGCGCGATGTACTTGCCGAATCCGACTCTCCATGGGTGGTCTCGCTCTTCTATTC
CTTCCAGGACCCGACGTATCTATACCTGGTCATGGAATTCCTGCCGGGCGGGGATCTGATGACCATGCTAATCAA
GTACGACACGTTCTCCGAGGATGTTACGCGATTCTACATGGCAGAGTGCGTTCTCGCCATTGAAGCTGTCCATCG
AATGGGATTCATCCATCGAGACATCAAACCGGATAACATTCTGATGTGGGTGTCTCCATCTTCTATCTTATTTGG
GATTGTGACTGGATTACTGACCTATATGGTAACATTAGCGACAAAGACGGACATATCAAGCTGAGCGACTTTGGT
CTTTCCACTGGTTTCCACAAGCAGCATGATTCGAGTTATTACCAACGCTTGTTAGAATCGGCCAAAAACTCGTCG
AATAATACACCTCAGTCGTCGAGGAACAGCGTCATGGTAAATTCCATCAACCTCACTATCAGTAATCAAGATATT
GCAACATGGAAAGCTAATCGACGGAAACTTGTAAGCAAGAACTTTTTCCACTGGAGGGAGAATAATTATCGTACT
CACATTCTGGGTTAGGCCTACTCCACTGTCGGTACTCCCGATTACATCGCTCCAGAAATCTTCCTCCAAAAGGGA
TATGGAAAGGAGTGTGACTGGTGGTCACTGGGTGCTATCATGTTCGAGTGTTTGGTGGGATACCCTCCATTCTGC
TCCGAATCCACCCACGAGACATATCAGAAGATCATTCATTGGCGCCATTGCCTTTCTTTCCCGAGCGATATTCAT
CTGAGCGCGGAGGCATTGGATCTAATACAAAGGTAGACTCGCTCTGGTCCACTTACACCGGATACAGGTGCTGAT
AACTAAATTACCCTGCACCCCTCAGGATGATCACCTCTGCTGACCAGAGGCTAAATGTGGACCAAATCAAGCGAC
ATCCATTCTTCTATGGTGTGGACTGGGCTACCATTCGACAGATAGACGCGCCGTTCGTTCCTCGGCTAAGCTCGA
TCACCGACACATCATATTTCCCAACGGACGAAATCGACCAAGTCACGGACGATATTCCCCAGGATGCTTCGTCCG
CGGACAAGGATCTTGCATTTCTTGGGTCTGTACTGTTGCTGCAATCATCTTGCCGATTGGGTCTATTGCTGACAC
GTTTGCTTTTAGATACACCTTCAAAAGGTTTTCAATATCTTCGCATGCATTCTAAGGTTGCTCCTGCCATTTTCT
GCTGGTTCAGACGCCCTGCATGGGGTGAGACAATGTTCTAACAATAGATCGCACGTTTATAAGTAGCAGGAATGT
ATGGCCACAAGATGATAATCTATTTCAGTTGTAACAGCC
Length 2214