CopciAB_82437
Coprinopsis cinerea A43mutB43mut pab1-1 #326

General data

Systematic name CopciAB_82437 Strain Coprinopsis cinerea Okayama 7
Standard name YCK2 Synonyms 82437
Uniprot id Functional description Belongs to the protein kinase superfamily
Location scaffold_2:1207915..1210404 Strand -
Gene length (nt) 2490 Transcript length (nt) 1906
CDS length (nt) 1377 Protein length (aa) 458

Reciprocal best hits in model fungi

Strain name Gene / Protein name
Saccharomyces cerevisiae YNL154C_YCK2
Aspergillus nidulans AN5757_ckiB
Schizosaccharomyces pombe cki1
Neurospora crassa ck-1b

Orthologs in mushroom models

Strain name Gene / Protein name Pident E-value Bits
Agrocybe aegerita Agrae_CAA7271540 79.7 3.446E-251 770
Hypsizygus marmoreus strain 51987-8 Hypma_RDB20985 79.3 1.912E-250 768
Lentinula edodes NBRC 111202 Lenedo1_1119959 77.5 3.95E-249 764
Lentinula edodes W1-26 v1.0 Lentinedodes1_8522 77.5 3.92E-249 764
Pleurotus ostreatus PC15 PleosPC15_2_1061144 80 9.849E-246 754
Pleurotus ostreatus PC9 PleosPC9_1_114233 79.7 4.752E-245 752
Pleurotus eryngii ATCC 90797 Pleery1_1409272 79.6 2.814E-244 750
Agaricus bisporus var bisporus (H97) Agabi_varbisH97_2_133794 78.2 4.588E-244 749
Agaricus bisporus var. burnettii JB137-S8 Agabi_varbur_1_82289 78.2 4.78E-244 749
Flammulina velutipes Flave_chr10AA00361 78.2 2.18E-237 730
Ganoderma sp. 10597 SS1 v1.0 Gansp1_129802 76.1 2.593E-235 724
Lentinula edodes B17 Lened_B_1_1_1518 75.8 7.768E-230 708
Grifola frondosa Grifr_OBZ75449 81.3 3.136E-215 666
Schizophyllum commune H4-8 Schco3_52195 93 3.21E-190 594
Auricularia subglabra Aurde3_1_1275237 63.2 4.997E-189 591

Expression

Name Summary Attribution Assay type
Carbon metabolism Transcriptional changes along alternative morphogenetic paths of C. cinerea Xie et al. 2020 RNA-Seq
Sample Mean cpm SD cpm Se of mean
sclerotia 161.4169 1.6348 0.9438
oidia 129.6264 14.3879 8.3068
vegetative_mycelium 111.1612 11.3141 6.5322
primordia 240.4579 13.7735 7.9521
hyphal_knot 141.3362 7.1527 4.1296
young_fruiting_body 309.071 21.0301 12.1418
Complex carbon sources 1 (long incubation) Expression profiling on diverse complex carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Control - glucose 142.6304 7.4453 4.2986
Wheat bran 101.4057 12.8128 7.3975
Horse manure 120.9992 35.3224 20.3934
Oak leaves 147.7784 33.2916 19.2209
Hay 136.7153 28.0472 16.193
Corn stalk 121.0262 15.8063 9.1257
Pectine 132.2639 7.6848 4.4368
Microcrystalline cellulose 129.9223 7.9859 4.6107
Xylose 154.3739 19.144 11.0528
Cellobiose 150.2117 8.5941 4.9618
Lignin 132.1266 30.7245 17.7388
Apple peels 162.459 9.1569 5.2867
Coprinopsis challenged with bacteria Transcriptional response to Bacillus subtilis and Escherichia coli. Kombrink et al. 2018 RNA-Seq
Sample Mean cpm SD cpm Se of mean
Control 142.0658 6.7206 3.8801
Bsubtilis 159.3904 7.2664 4.1953
Ecoli 137.3423 5.9877 3.457
Early development 1 Time series expression profiling of basidiospore and oidium germination Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
BS 0h 98.965 4.5331 2.6172
BS 4h 62.0786 4.5486 2.6261
BS 8h 77.1001 6.4058 3.6984
BS 12h 98.353 10.4488 6.0326
Oidia 0 h 73.0117 10.327 5.9623
Oidia 18 h 85.7788 19.341 11.1665
Sclerotia 148.9903 22.8745 13.2066
Early development 2 Time series expression profiling of mycelial growth, light induction and fruiting body initiation. Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
DM 12h 202.4797 52.9176 30.552
DM 36h 187.6073 10.9978 6.3496
DM 60h 167.7699 17.3117 9.9949
DM 84h 176.799 4.2009 2.4254
DM 108h 187.9957 14.4666 8.3523
DM 132h 199.6049 17.802 10.278
DM 156hAE 232.1508 7.7372 4.4671
ELI1hAE 208.4542 25.629 14.7969
ELI2hAE 192.2427 19.326 11.1579
LI2hAE 195.1344 28.7095 16.5754
LI6hAE 209.8828 8.64 4.9883
LI12hAE 196.0164 17.5467 10.1306
LI18hAE 210.7031 45.0313 25.9988
LI 24hAE 223.7115 15.8684 9.1616
DM 156hAM 165.9967 13.6302 7.8694
ELI1hAM 162.2316 6.991 4.0362
ELI2hAM 151.1648 8.4573 4.8828
LI2hAM 137.344 21.3205 12.3094
LI6hAM 161.8781 7.5718 4.3716
LI12hAM 159.2968 20.395 11.7751
LI18hAM 164.4385 14.1999 8.1983
LI 24hAM 198.5134 21.3859 12.3472
LI 24hHK 168.0701 12.0919 6.9813
L/D 6h 209.7859 33.0405 19.0759
L/D 12h 203.4905 38.8021 22.4024
L/D 18h 181.2066 26.5335 15.3191
L/D 24h 193.0852 25.0748 14.4769
Fruiting body development RNA-Seq analysis of fruiting body development Krizsan et al. 2019 RNA-Seq
Sample Mean cpm SD cpm Se of mean
Vegetative mycelium 97.3183 5.1005 2.9448
Hyphal knots 128.8966 15.0946 8.7149
Primordium 1 130.0317 18.4149 10.6319
Primordium 2 117.3379 8.9161 5.1477
Young Fruiting body cap 321.1315 156.642 90.4373
Younf fruiting body gill 227.6724 16.5348 9.5463
Young fruiting body stipe 452.0675 159.6053 92.1482
Mature fruiting body cap_gill 390.6154 53.9963 31.1748
Mature fruiting body stipe 939.5182 102.6132 59.2438
Nitrogen sources (12h incubation) Expression profiling on diverse nitrogen sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Complete medium - control 134.4534 10.047 5.8006
NH4NO3 120.6525 2.5417 1.4675
Proline 149.2046 7.4028 4.274
Tryptophan 149.944 13.0321 7.5241
Isoleucin 149.1593 3.9888 2.3029
Arginine 148.5061 8.7394 5.0457
Metionine 156.359 9.4823 5.4746
NaNO3 135.0633 6.8218 3.9386
Plant biomass (12h incubation) Expression profiling on diverse plant biomasses as carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose - control 134.4534 10.047 5.8006
Citrus peel 171.4414 13.7415 7.9336
Poplar leaves 152.8759 10.5019 6.0633
Typha leaves 154.8865 8.4473 4.8771
Overwintered Salix leaves 154.7419 16.3114 9.4174
Reed flowering 190.7917 52.1935 30.1339
Tigernut 155.4559 3.3876 1.9558
Energy cane 144.8293 16.1048 9.2981
Guar gum 163.0473 43.9376 25.3674
Apple peels 139.2882 12.3018 7.1024
Cellobiose 134.3391 7.9017 4.562
Corn stalk 131.8339 16.1396 9.3182
Horse manure 127.8867 14.2093 8.2038
Lignin 131.3101 14.4079 8.3184
Microcrystalline cellulose 145.818 4.6727 2.6978
Oak leaves 128.4472 10.4852 6.0536
Pectin esterified 131.4809 3.8982 2.2506
Poplar sawdust 146.6456 12.1238 6.9997
Wheat bran 120.3129 10.1681 5.8706
Chlamydomonas reinhardtii 143.6976 7.5576 4.3634
Vertatryl alcohol 97.1735 2.7066 1.5627
Furfural 111.7706 18.3212 10.5778
Autoclaved mycelium 133.8038 3.4053 1.966
Simple and complex carbon and nitrogen sources Expression profiling on diverse complex carbon and nitrogen sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose control 119.9201 5.4204 3.1294
Ribose 141.4729 6.9032 3.9856
Mannose 128.4109 3.69 2.6092
Fructose 137.6156 0.9592 0.5538
Arabinose 139.47 5.2909 3.0547
Xylose 133.4279 5.3678 3.0991
Galacturonic acid 137.061 13.2505 7.6502
Rhamnogalacturonan 139.6025 8.5896 4.9592
Pectin esterified 141.1598 4.3877 2.5332
Polygalacturonic acid 133.4545 4.5104 2.6041
Sodium acetate 138.7429 9.3902 5.4214
No nitrogen 147.7473 3.8806 2.2405
BSA 135.8162 6.9472 4.0109
Glutamine 134.0103 5.4981 3.1743
No phosphate 139.7816 4.3543 2.5139
No carbon 147.7305 2.3153 1.6371
No sulphur 137.8773 8.9403 5.1617
Simple and complex carbon sources (12h incubation) Expression profiling on diverse complex carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose - control 134.4534 10.047 5.8006
Amylose 151.6859 4.4285 2.5568
Fucose 148.7439 11.6291 6.714
Galactose 149.827 8.8949 5.1354
Lactose 125.3755 9.657 5.5755
Maltose 137.2443 2.5852 1.4926
Mannitol 133.9897 14.1966 8.1964
Rhamnose 146.0139 6.5305 3.7704
Sorbitol 124.3802 4.1213 2.3795
Trehalose 119.8863 6.3669 3.676
Glycerol 152.9312 7.4064 4.2761
Glucuronic acid 142.7229 7.8119 4.5102
Arabinan 150.1408 4.4682 2.5797
Galactan 148.9022 5.6669 3.2718
Galactomannan 150.5052 34.6019 19.9774
Glucan 149.7815 10.0716 5.8148
Xylan 129.0852 4.3392 2.5052
Xyloglucan 131.494 9.1124 5.2611
Arabinogalactan 150.0019 8.1429 4.7013
Pectin 121.808 7.5395 4.3529
Rhamnogalacturonan 107.6616 15.9706 9.2206
Polygalacturonic acid 129.68 11.0996 6.4083
Mannan 145.2624 7.0159 4.0506
Amylopectin 152.6985 9.6273 5.5583
Inulin 153.2322 7.8015 4.5042
BSA 140.228 19.8615 11.467
Starvation induced by water agar transfer Expression profiling on starvation induced by transfer to water agar Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Control 167.7699 17.3117 9.9949
2h WAT 188.5383 5.955 3.4381
4h WAT 199.4755 9.1348 5.274
8h WAT 214.4915 12.2564 7.0762
16h WAT 201.0873 14.4788 8.3594
24h WAT 207.1859 8.9353 5.1588
WAT hyphal knot -30h 231.4966 9.226 5.3266
WAT hyphal knot -22h 224.0675 9.2208 5.3236
WAT hyphal knot -15h 214.1881 12.3619 7.1372
WAT hyphal knot -7.5h 251.8986 41.5356 23.9806
WAT hyphal knot 233.4559 34.9404 20.1728
WAT hyphal knot +7.5h 192.0021 12.4085 7.1641
Straw time series Time series expression profiling on straw as a carbon source Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose control 142.289 27.4786 15.8648
Straw 3h 142.318 17.1646 9.91
Straw 6h 133.1465 26.1629 15.1052
Straw 12h 129.1295 15.2117 8.7825
Straw 24h 162.623 44.5203 25.7038
Stress conditions 1 Expression profiling under various stress conditions Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Flask control 224.1709 26.3254 15.199
Frost (-20C, 30min) 182.2105 11.9809 6.9172
Heat shock (47C, 2h) 65.1433 0.8115 0.4685
High CO2 152.5071 22.7105 13.1119
Drought (4% agar, 12h) 134.9071 28.8554 16.6597
Oxidative (1mM H2O2, 3h) 133.1688 19.7128 11.3812
Acidic (pH4, 3h) 159.3987 13.2552 7.6529
Alkaline (pH9, 3h) 179.5537 16.3507 9.4401
Osmotic (sorbitol 2h) 184.7244 45.9752 26.5438
CongoRed (3h) 195.5465 22.727 13.1214
Cobalt chloride control 188.2212 8.4727 4.8917
Cobalt chloride 2mM 214.0015 24.0072 13.8606
Stress conditions 2 Expression profiling under various stress conditions Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Flask control 131.4078 22.549 13.0187
Cold stimulation 148.2018 25.5455 14.7487
Scratched surface 219.4018 17.2744 9.9734
Ca2+, 200mM, 24h 109.3682 27.3905 15.8139
Cu2+, 2mM, 6h 128.6133 4.8752 2.8147
Voriconazole 166.2488 4.836 2.7921
Trichoderma interaction, early 183.64 21.3599 12.3321
Trichoderma interaction 60h 137.6077 42.2597 24.3987
Cobalt chloride 2mM repeat 169.7102 37.7246 21.7803
Hypoxia 172.5785 41.038 23.6933
Hypoxia control 150.4664 36.4091 21.0208
Protoplastation control 203.4961 1.9009 1.3441
Protoplastation 3.5h 152.3023 25.3948 17.9568
Protoplastation 1.5h 213.4761 25.3415 17.9192

General data

Systematic name YCK2
Protein id CopciAB_82437.T0
Description Belongs to the protein kinase superfamily

Annotation summary

0 100 200 300 400 458

Conserved domains

Analysis Signature accession Signature description InterPro Accession Start End
CDD cd14127 STKc_CK1_fungal - 17 293
Pfam PF00069 Protein kinase domain IPR000719 18 238

SignalP

Prediction Start End Score
No records

Transmembrane domains

Domain n Start End Length
No records

InterPro

Accession Description
IPR000719 Protein kinase domain
IPR008271 Serine/threonine-protein kinase, active site
IPR011009 Protein kinase-like domain superfamily
IPR017441 Protein kinase, ATP binding site

GO

Go id Term Ontology
GO:0004672 protein kinase activity MF
GO:0005524 ATP binding MF
GO:0006468 protein phosphorylation BP

KEGG

KEGG Orthology
K02218

EggNOG

COG category Description
T Belongs to the protein kinase superfamily

CAZy

Class Family Subfamily
No records

Transcription factor

Group
No records

Conservation of CopciAB_82437 across fungi.

Arrow shows the origin of gene family containing CopciAB_82437.

Protein

Sequence id CopciAB_82437.T0
Sequence >CopciAB_82437.T0
MASHSHPSSTANIVGIHYRVGKKIGEGSFGVIFEGTNLLNSQTVAIKFEPRKAEAPQLRDECRSYRILAGCTGIP
QIYHFGQEGLHNILVIDLLGPSLEDLFDMCGRKFSIKTVCMAAKQMITRVQTIHEKNLIYRDIKPDNFLIGRPGT
KGANVIHVVDFGMAKQYRDPKTKQHIPYRERKSLSGTARYMSINTHLGREQSRRDDLEALGHVFMYFLRGSLPWQ
GLKAATNKQKYEKIGEKKQTTPIKELCEGFPEEFGIYLNYVRKLGFEETPDYDFLRELFTKVLKSNGDVEDNVFD
WNLLNDGRGWEASLNQSQILPPMQPTNDRRRGDGREDRRRSQQGVVPPSPALVRTGSKQRKGPGAGQMTPHMNVP
AANRMSGAQHPYANAGGYDYGAVDDPYRNQPYGRASPMVPNASAAPPTMTNARASATPGDYNQQGGEEPAPKPSL
LRILTCRC
Length 458

Coding

Sequence id CopciAB_82437.T0
Sequence >CopciAB_82437.T0
ATGGCCTCCCATTCACACCCATCGTCGACAGCGAACATAGTTGGCATCCACTATCGTGTCGGCAAGAAGATTGGA
GAGGGCTCGTTTGGCGTAATCTTCGAGGGCACCAATCTGCTCAACTCTCAAACGGTCGCCATCAAGTTTGAACCA
AGAAAGGCGGAAGCGCCCCAGCTTCGGGATGAATGTCGCTCTTATCGTATTCTGGCGGGCTGCACTGGAATCCCC
CAAATATACCATTTCGGTCAAGAAGGCTTGCACAACATCCTCGTAATTGACCTTCTTGGTCCAAGTCTTGAAGAT
CTCTTCGACATGTGTGGTCGCAAGTTCAGCATCAAGACCGTTTGCATGGCAGCCAAGCAAATGATTACTCGTGTC
CAGACCATCCATGAGAAGAACCTCATTTACCGCGACATTAAGCCAGACAACTTTTTGATTGGTCGTCCAGGCACC
AAGGGGGCCAACGTTATCCACGTTGTCGACTTTGGAATGGCGAAGCAGTACCGTGACCCGAAGACGAAGCAGCAC
ATCCCCTATCGGGAACGGAAGAGTCTCAGCGGAACCGCGCGGTACATGAGCATCAATACGCACCTGGGCAGAGAG
CAATCTAGAAGAGATGATCTCGAAGCTCTTGGTCATGTATTCATGTACTTTTTACGTGGTAGCCTGCCATGGCAA
GGTTTGAAGGCCGCTACCAACAAGCAGAAGTACGAGAAGATTGGAGAGAAGAAGCAAACTACGCCAATTAAAGAG
CTATGCGAAGGATTTCCAGAGGAGTTTGGCATTTATCTGAACTATGTTCGCAAACTTGGATTCGAAGAGACGCCC
GATTACGACTTCTTGCGTGAATTGTTCACCAAGGTTCTAAAGAGCAATGGTGATGTTGAGGATAATGTATTTGAC
TGGAACTTACTTAACGATGGTCGGGGCTGGGAAGCTTCGTTGAATCAAAGCCAAATTTTGCCTCCAATGCAACCC
ACTAACGATAGACGACGCGGCGATGGCCGTGAAGATCGTAGACGATCCCAACAGGGTGTTGTACCACCGTCGCCC
GCTCTCGTACGAACTGGCTCGAAGCAACGCAAGGGCCCGGGCGCGGGCCAGATGACACCGCACATGAACGTTCCT
GCGGCCAATCGTATGAGTGGGGCACAGCATCCTTATGCAAACGCAGGGGGGTATGACTACGGTGCGGTGGACGAT
CCTTATCGCAACCAACCGTATGGTCGCGCATCCCCCATGGTGCCTAATGCTAGCGCCGCACCACCCACCATGACC
AACGCACGAGCGTCTGCCACTCCAGGGGACTACAATCAGCAAGGTGGCGAAGAGCCTGCACCAAAACCATCCCTG
CTCCGAATCTTGACATGTAGATGTTGA
Length 1377

Transcript

Sequence id CopciAB_82437.T0
Sequence >CopciAB_82437.T0
ATTTCCCTTTCCTTCTTCCCTCCGACGCCCTCCTCCTATCAGCAATCGTCCCCGACGACGACGACGACGACGACC
ATGGCCTCCCATTCACACCCATCGTCGACAGCGAACATAGTTGGCATCCACTATCGTGTCGGCAAGAAGATTGGA
GAGGGCTCGTTTGGCGTAATCTTCGAGGGCACCAATCTGCTCAACTCTCAAACGGTCGCCATCAAGTTTGAACCA
AGAAAGGCGGAAGCGCCCCAGCTTCGGGATGAATGTCGCTCTTATCGTATTCTGGCGGGCTGCACTGGAATCCCC
CAAATATACCATTTCGGTCAAGAAGGCTTGCACAACATCCTCGTAATTGACCTTCTTGGTCCAAGTCTTGAAGAT
CTCTTCGACATGTGTGGTCGCAAGTTCAGCATCAAGACCGTTTGCATGGCAGCCAAGCAAATGATTACTCGTGTC
CAGACCATCCATGAGAAGAACCTCATTTACCGCGACATTAAGCCAGACAACTTTTTGATTGGTCGTCCAGGCACC
AAGGGGGCCAACGTTATCCACGTTGTCGACTTTGGAATGGCGAAGCAGTACCGTGACCCGAAGACGAAGCAGCAC
ATCCCCTATCGGGAACGGAAGAGTCTCAGCGGAACCGCGCGGTACATGAGCATCAATACGCACCTGGGCAGAGAG
CAATCTAGAAGAGATGATCTCGAAGCTCTTGGTCATGTATTCATGTACTTTTTACGTGGTAGCCTGCCATGGCAA
GGTTTGAAGGCCGCTACCAACAAGCAGAAGTACGAGAAGATTGGAGAGAAGAAGCAAACTACGCCAATTAAAGAG
CTATGCGAAGGATTTCCAGAGGAGTTTGGCATTTATCTGAACTATGTTCGCAAACTTGGATTCGAAGAGACGCCC
GATTACGACTTCTTGCGTGAATTGTTCACCAAGGTTCTAAAGAGCAATGGTGATGTTGAGGATAATGTATTTGAC
TGGAACTTACTTAACGATGGTCGGGGCTGGGAAGCTTCGTTGAATCAAAGCCAAATTTTGCCTCCAATGCAACCC
ACTAACGATAGACGACGCGGCGATGGCCGTGAAGATCGTAGACGATCCCAACAGGGTGTTGTACCACCGTCGCCC
GCTCTCGTACGAACTGGCTCGAAGCAACGCAAGGGCCCGGGCGCGGGCCAGATGACACCGCACATGAACGTTCCT
GCGGCCAATCGTATGAGTGGGGCACAGCATCCTTATGCAAACGCAGGGGGGTATGACTACGGTGCGGTGGACGAT
CCTTATCGCAACCAACCGTATGGTCGCGCATCCCCCATGGTGCCTAATGCTAGCGCCGCACCACCCACCATGACC
AACGCACGAGCGTCTGCCACTCCAGGGGACTACAATCAGCAAGGTGGCGAAGAGCCTGCACCAAAACCATCCCTG
CTCCGAATCTTGACATGTAGATGTTGAGGACGAAGGGCATCGTTTCCAGCTTCTCTTATCCATTCACGAAAACGC
TCGTTTTGGCATCGTTAATATCTTCCTTAACGCCGTTCCAGTCTGCAGGACTTAATGACTCCACATCTTTCTCTC
GGGTGTTCTCTGCCTTCGTCGCTTTCGAGGTTGCTTTTTCCCTTTTGAATAGTTTTACAAGTCCGCTTCAGGTTA
CTCCTTCATGACGTCCAATTCTTTTGAGCCAGGCTTCGCTTGTTTTCTCCGTTTCCTCTAGTCCTCTGTCACTCT
TTTACTGTGTCACCGTGCCTTCTAGCTAGTCCTTATTCCGGTTCTTATTATTTTTATACCCATACAGCCACACCT
AATTGAAGGATCTTCAGACCTTCTTGACGATCCATACTTCCATTCCTTTCATAGTAACGCCCTGTACATGATGAC
CCAATCTATTCTACGGAAAGCTTGCTCTCGG
Length 1906

Gene

Sequence id CopciAB_82437.T0
Sequence >CopciAB_82437.T0
ATTTCCCTTTCCTTCTTCCCTCCGACGCCCTCCTCCTATCAGCAATCGTCCCCGACGACGACGACGACGACGACC
ATGGCCTCCCATTCACACCCATCGTCGACAGCGAACATAGTTGGCATCCACTATCGTGTCGGCAAGAAGATTGGA
GAGGGCTCGTTTGGCGTAATCTTCGAGGGTACAGCGCTTTCCATATGAATTTGTCGTCGTCATCGTCGTGCTCAA
CGGGTGCTGTTCACACTAGGCACCAATCTGCTCAACTCTCAAACGGTCGCCATCAAGTTTGTGCGTGCTCGACTC
CACGAAGTGCCTCTATCTCCGAACACGCCCAGCTCAATGCTTCTCACAGGAACCAAGAAAGGCGGAAGCGCCCCA
GCTTCGGGATGAATGTCGCTCTTATCGTATTCTGGCGGGCTGCAGTGCGTACTTCGTCACCACACCGTCCATCAC
CACCCCTCGCTTACCCGAACTGCTTAACAGCTGGAATCCCCCAAATATACCATTTCGGTCAAGAAGGCTTGCACA
ACATCCTCGTAATTGACCTTCTTGGTCCAAGTCTTGAAGATCTCTTCGACATGTGTGGTCGCAAGTTCAGCATCA
AGACCGTTTGCATGGCAGCCAAGCAAATGGTGCGCTCGACCGCTTGCTTCGCCCCTCGTCCTTGTCCTTCTCATT
CAAAGGACCTTCCATTGGCGTTCTCCTTCAACAGATTACTCGTGTCCAGACCATCCATGAGAAGAACCTCATTTA
CCGCGACATTAAGCCAGACAACTTTTTGATTGGTCGTCCAGGCACCAAGGGGGCCAACGGTCAGTTCATCTTCGG
CTTTTCAGATTTAGCACAGCAGCGGCATCTCTTAACTAATTCAAATTTAGTTATCCACGTTGTCGACTTTGGAAT
GGCGAAGCAGTACCGTGACCCGAAGACGAAGCAGCACATCCCCTATCGGGAACGGAAGAGTCTCAGCGGAACCGC
GCGGTACATGAGCATCAATACGCACCTGGGCAGAGGTCAGTCTTGCCATTTAAACTCACATTATTGCCCCTGATC
GTTATTTGCATTTACCCCTTTGCTACAGAGCAATCTAGAAGAGATGATCTCGAAGCTCTTGGTCATGTATTCATG
TACTTTTTACGTGGTAGCCTGCCATGGCAAGGTTTGAAGGCCGCTACCAACAAGCAGAAGTACGAGAAGATTGGA
GAGAAGAAGCAAACTACGCCAATTAAAGAGCTATGCGAAGGATTTCCAGGCAAGTTGCATCTGAATTAGGGTTTC
ACCCAAACCCCACTCATACCCTTGAGTCTCCAGAGGAGTTTGGCATTTATCTGAACTATGTTCGCAAACTTGGAT
TCGAAGAGACGCCCGATTACGACTTCTTGCGTGAATTGTTCACCAAGGTTCTAAAGAGCAATGGTGATGTTGAGG
ATAATGTATTTGACTGGAACTTACTTAACGGTGAGTCATTAAAAATGTACAAGTGATATTCAAATATTTATGGGC
CATAACCTTATAGATGGTCGGGGCTGGGAAGCTTCGTTGGTACGTTCTTGGCTTGCTCTGTGCCTTTGCGTGACC
TTGGTTGACTTTCATTCGCTGTCTAGAATCAAAGCCAAATTTTGCCTCCAATGCAACCCACTAACGATAGACGAC
GCGGCGATGGCCGTGAAGATCGTAGACGATCCCAACAGGGTGTTGTACCACCGTCGCCCGCTCTCGTACGAACTG
GCTCGAAGCAACGCAAGGGCCCGGGCGCGGGCCAGATGACACCGCACATGAACGTTCCTGCGGCCAATCGTATGA
GTGGGGCACAGCATCCTTATGCAAACGCAGGGGGGTATGACTACGGTGCGGTGGACGATCCTTATCGCAACCAAC
CGTATGGTCGCGCATCCCCCATGGTGCCTAATGCTAGCGCCGCACCACCCACCATGACCAACGCACGAGCGTCTG
CCACTCCAGGGGACTACAATCAGCAAGGTGGCGAAGAGCCTGCACCAAAACCATCCCTGCTCCGAATCTTGACAT
GTAGATGTTGAGGACGAAGGGCATCGTTTCCAGCTTCTCTTATCCATTCACGAAAACGCTCGTTTTGGCATCGTT
AATATCTTCCTTAACGCCGTTCCAGTCTGCAGGACTTAATGACTCCACATCTTTCTCTCGGGTGTTCTCTGCCTT
CGTCGCTTTCGAGGTTGCTTTTTCCCTTTTGAATAGTTTTACAAGTCCGCTTCAGGTTACTCCTTCATGACGTCC
AATTCTTTTGAGCCAGGCTTCGCTTGTTTTCTCCGTTTCCTCTAGTCCTCTGTCACTCTTTTACTGTGTCACCGT
GCCTTCTAGCTAGTCCTTATTCCGGTTCTTATTATTTTTATACCCATACAGCCACACCTAATTGAAGGATCTTCA
GACCTTCTTGACGATCCATACTTCCATTCCTTTCATAGTAACGCCCTGTACATGATGACCCAATCTATTCTACGG
AAAGCTTGCTCTCGG
Length 2490