CopciAB_357261
Coprinopsis cinerea A43mutB43mut pab1-1 #326

General data

Systematic name CopciAB_357261 Strain Coprinopsis cinerea Okayama 7
Standard name - Synonyms 357261
Uniprot id Functional description Protein tyrosine kinase
Location scaffold_1:1830717..1832936 Strand -
Gene length (nt) 2220 Transcript length (nt) 1519
CDS length (nt) 1395 Protein length (aa) 464

Reciprocal best hits in model fungi

Strain name Gene / Protein name

Orthologs in mushroom models

Strain name Gene / Protein name Pident E-value Bits
Hypsizygus marmoreus strain 51987-8 Hypma_RDB28880 62.8 5.135E-188 588
Lentinula edodes NBRC 111202 Lenedo1_1125164 61 2.104E-178 560
Pleurotus eryngii ATCC 90797 Pleery1_1485638 56.7 4.573E-169 533
Schizophyllum commune H4-8 Schco3_2684163 52.4 2.881E-157 499
Grifola frondosa Grifr_OBZ79927 53.7 2.749E-155 493
Ganoderma sp. 10597 SS1 v1.0 Gansp1_38805 51.4 1.019E-138 445
Pleurotus ostreatus PC15 PleosPC15_2_49595 62.7 1.031E-137 442
Pleurotus ostreatus PC9 PleosPC9_1_96060 62.7 1.009E-137 442
Lentinula edodes W1-26 v1.0 Lentinedodes1_878 50.5 1.517E-134 433
Auricularia subglabra Aurde3_1_1405448 40.8 5.22E-103 342
Flammulina velutipes Flave_chr08AA01171 35.3 3.701E-45 171

Expression

Name Summary Attribution Assay type
Carbon metabolism Transcriptional changes along alternative morphogenetic paths of C. cinerea Xie et al. 2020 RNA-Seq
Sample Mean cpm SD cpm Se of mean
sclerotia 13.0781 3.5746 2.0638
oidia 1.536 0.6413 0.3703
vegetative_mycelium 1.5981 0.734 0.4238
primordia 95.8509 2.9392 1.697
hyphal_knot 3.7632 1.9344 1.1168
young_fruiting_body 37.7277 11.92 6.882
Complex carbon sources 1 (long incubation) Expression profiling on diverse complex carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Control - glucose 2.804 0.8773 0.5065
Wheat bran 0.9772 0.012 0.0069
Horse manure 1.1254 0.3783 0.2184
Oak leaves 0.758 0.2116 0.1222
Hay 1.1226 0.6521 0.3765
Corn stalk 0.7885 0.0984 0.0568
Pectine 0.871 0.0685 0.0395
Microcrystalline cellulose 0.8256 0.3439 0.1985
Xylose 0.5971 0.2706 0.1562
Cellobiose 1.1074 0.3358 0.1939
Lignin 1.5298 0.3473 0.2005
Apple peels 3.1082 0.8726 0.5038
Coprinopsis challenged with bacteria Transcriptional response to Bacillus subtilis and Escherichia coli. Kombrink et al. 2018 RNA-Seq
Sample Mean cpm SD cpm Se of mean
Control 0.8799 0.208 0.1201
Bsubtilis 0.9362 0.2365 0.1366
Ecoli 1.0969 0.1424 0.0822
Early development 1 Time series expression profiling of basidiospore and oidium germination Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
BS 0h 7.6753 1.8147 1.0477
BS 4h 6.6939 0.4893 0.2825
BS 8h 2.9213 0.4678 0.2701
BS 12h 1.4508 0.5043 0.2911
Oidia 0 h 2.0852 0.8142 0.4701
Oidia 18 h 2.3981 0.9281 0.5358
Sclerotia 0.3789 0.5977 0.3451
Early development 2 Time series expression profiling of mycelial growth, light induction and fruiting body initiation. Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
DM 12h 0.5008 0.2374 0.137
DM 36h 0.362 0.1963 0.1133
DM 60h 0.1652 0.0845 0.0488
DM 84h 0.3228 0.1933 0.1116
DM 108h 0.0921 0.0808 0.0467
DM 132h 0.2732 0.252 0.1455
DM 156hAE 0.0545 0.0475 0.0274
ELI1hAE 0.1136 0.0991 0.0572
ELI2hAE 0.3503 0.4062 0.2345
LI2hAE 0.031 0.0538 0.031
LI6hAE 0.2011 0.3483 0.2011
LI12hAE 0.3373 0.324 0.1871
LI18hAE 0.4668 0.5845 0.3375
LI 24hAE 0.3056 0.27 0.1559
DM 156hAM 0.1804 0.2368 0.1367
ELI1hAM 0.0931 0.0904 0.0522
ELI2hAM 0.2611 0.103 0.0595
LI2hAM 0.1045 0.108 0.0623
LI6hAM 0.3501 0.4015 0.2318
LI12hAM 0.5189 0.8987 0.5189
LI18hAM 0.3551 0.3499 0.202
LI 24hAM 0.4318 0.7479 0.4318
LI 24hHK 1.2069 0.643 0.3712
L/D 6h 2.1658 1.5377 0.8878
L/D 12h 1.1833 0.8412 0.4857
L/D 18h 2.8839 0.634 0.366
L/D 24h 3.8122 1.2395 0.7156
Fruiting body development RNA-Seq analysis of fruiting body development Krizsan et al. 2019 RNA-Seq
Sample Mean cpm SD cpm Se of mean
Vegetative mycelium 1.347 0.5352 0.309
Hyphal knots 5.6214 0.4889 0.2823
Primordium 1 11.1888 6.026 3.4791
Primordium 2 11.193 2.5564 1.4759
Young Fruiting body cap 28.2842 16.2378 9.3749
Younf fruiting body gill 53.8396 12.5761 7.2608
Young fruiting body stipe 108.0626 45.5087 26.2744
Mature fruiting body cap_gill 7.0854 1.8868 1.0893
Mature fruiting body stipe 35.6784 12.8832 7.4381
Nitrogen sources (12h incubation) Expression profiling on diverse nitrogen sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Complete medium - control 0.7396 0.3879 0.224
NH4NO3 0.7941 0.0733 0.0423
Proline 0.2872 0.1678 0.0969
Tryptophan 0.5813 0.443 0.2558
Isoleucin 0.5581 0.1552 0.0896
Arginine 0.9411 0.1707 0.0986
Metionine 0.404 0.2866 0.1654
NaNO3 0.6516 0.1048 0.0605
Plant biomass (12h incubation) Expression profiling on diverse plant biomasses as carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose - control 0.7396 0.3879 0.224
Citrus peel 1.7355 0.8344 0.4818
Poplar leaves 1.0706 0.3742 0.2161
Typha leaves 1.5591 0.1696 0.0979
Overwintered Salix leaves 0.9957 0.2538 0.1465
Reed flowering 0.923 0.2958 0.1708
Tigernut 0.7347 0.4513 0.2605
Energy cane 1.0899 0.1454 0.084
Guar gum 0.7348 0.2262 0.1306
Apple peels 0.6515 0.4939 0.2852
Cellobiose 0.4295 0.1265 0.073
Corn stalk 0.8631 0.3247 0.1874
Horse manure 0.7006 0.4298 0.2482
Lignin 1.3705 0.2636 0.1522
Microcrystalline cellulose 0.4764 0.3684 0.2127
Oak leaves 0.9363 0.5902 0.3407
Pectin esterified 0.7993 0.0836 0.0483
Poplar sawdust 0.4835 0.2392 0.1381
Wheat bran 1.4092 0.3243 0.1872
Chlamydomonas reinhardtii 1.3821 0.067 0.0387
Vertatryl alcohol 4.5876 0.6015 0.3472
Furfural 4.8042 0.3245 0.1873
Autoclaved mycelium 1.0959 0.0555 0.032
Simple and complex carbon and nitrogen sources Expression profiling on diverse complex carbon and nitrogen sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose control 0.7869 0.063 0.0364
Ribose 0.5376 0.3611 0.2085
Mannose 0.4509 0.1521 0.1075
Fructose 0.7053 0.3845 0.222
Arabinose 0.462 0.2933 0.1693
Xylose 0.6691 0.5172 0.2986
Galacturonic acid 0.5669 0.3997 0.2307
Rhamnogalacturonan 0.472 0.3001 0.1733
Pectin esterified 0.8661 0.6046 0.3491
Polygalacturonic acid 0.5996 0.2681 0.1548
Sodium acetate 0.2503 0.0631 0.0364
No nitrogen 0.9501 0.2622 0.1514
BSA 0.6796 0.2362 0.1364
Glutamine 1.3164 0.5229 0.3019
No phosphate 0.6411 0.2921 0.1686
No carbon 1.382 0.3069 0.217
No sulphur 0.6227 0.1155 0.0667
Simple and complex carbon sources (12h incubation) Expression profiling on diverse complex carbon sources. Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose - control 0.7396 0.3879 0.224
Amylose 0.7027 0.1921 0.1109
Fucose 0.7459 0.2734 0.1579
Galactose 0.6321 0.0759 0.0438
Lactose 0.8598 0.4991 0.2882
Maltose 1.1191 0.364 0.2102
Mannitol 0.7113 0.1287 0.0743
Rhamnose 0.811 0.4026 0.2325
Sorbitol 0.7058 0.5881 0.3396
Trehalose 0.5847 0.1618 0.0934
Glycerol 0.6366 0.2768 0.1598
Glucuronic acid 0.6479 0.0728 0.0421
Arabinan 0.6113 0.2459 0.142
Galactan 1.5543 0.3866 0.2232
Galactomannan 1.0716 0.0342 0.0197
Glucan 1.2464 0.7835 0.4523
Xylan 0.8582 0.3338 0.1927
Xyloglucan 0.7784 0.2936 0.1695
Arabinogalactan 0.7088 0.171 0.0987
Pectin 2.3709 1.1166 0.6447
Rhamnogalacturonan 2.4886 0.9428 0.5443
Polygalacturonic acid 0.8657 0.3685 0.2128
Mannan 0.5661 0.0491 0.0284
Amylopectin 1.1305 0.5197 0.3001
Inulin 1.0758 0.7472 0.4314
BSA 0.6347 0.3069 0.1772
Starvation induced by water agar transfer Expression profiling on starvation induced by transfer to water agar Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Control 0.1652 0.0845 0.0488
2h WAT 0.3318 0.4205 0.2428
4h WAT 0.2479 0.2472 0.1427
8h WAT 0.0782 0.0718 0.0414
16h WAT 0.4183 0.3623 0.2092
24h WAT 0 0 0
WAT hyphal knot -30h 0.0878 0.0876 0.0506
WAT hyphal knot -22h 0.1273 0.1523 0.0879
WAT hyphal knot -15h 0.1267 0.1294 0.0747
WAT hyphal knot -7.5h 0.0835 0.1446 0.0835
WAT hyphal knot 0.1271 0.2201 0.1271
WAT hyphal knot +7.5h 0.1621 0.1745 0.1008
Straw time series Time series expression profiling on straw as a carbon source Hegedus et al. RNA-Seq
Sample Mean cpm SD cpm Se of mean
Glucose control 0.6011 0.13 0.0751
Straw 3h 2.036 0.5389 0.3111
Straw 6h 2.247 0.455 0.2627
Straw 12h 0.8213 0.3454 0.1994
Straw 24h 1.0504 0.6186 0.3571
Stress conditions 1 Expression profiling under various stress conditions Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Flask control 0.5039 0.2707 0.1563
Frost (-20C, 30min) 0.9913 0.2938 0.1696
Heat shock (47C, 2h) 2.0023 1.0481 0.6051
High CO2 0.297 0.1865 0.1077
Drought (4% agar, 12h) 0.3098 0.1658 0.0958
Oxidative (1mM H2O2, 3h) 1.0554 0.79 0.4561
Acidic (pH4, 3h) 0.7213 0.6148 0.355
Alkaline (pH9, 3h) 0.2673 0.0491 0.0283
Osmotic (sorbitol 2h) 1.9945 0.5976 0.345
CongoRed (3h) 0.9139 0.5953 0.3437
Cobalt chloride control 0.5449 0.4641 0.268
Cobalt chloride 2mM 0.3676 0.159 0.0918
Stress conditions 2 Expression profiling under various stress conditions Hegedus et al. QuantSeq
Sample Mean cpm SD cpm Se of mean
Flask control 0.2079 0.3267 0.1886
Cold stimulation 0.2402 0.3037 0.1753
Scratched surface 0.1353 0.1185 0.0684
Ca2+, 200mM, 24h 1.1654 0.7185 0.4148
Cu2+, 2mM, 6h 0.4737 0.4316 0.2492
Voriconazole 0.6197 0.4193 0.2421
Trichoderma interaction, early 0.2968 0.4021 0.2322
Trichoderma interaction 60h 8.8752 10.6744 6.1629
Cobalt chloride 2mM repeat 0.2232 0.2039 0.1177
Hypoxia 0.5091 0.5146 0.2971
Hypoxia control 0.1901 0.165 0.0953
Protoplastation control 0.1206 0.0168 0.0119
Protoplastation 3.5h 0 0 0
Protoplastation 1.5h 0.7398 1.0462 0.7398

General data

Systematic name -
Protein id CopciAB_357261.T0
Description Protein tyrosine kinase

Annotation summary

0 100 200 300 400 464

Conserved domains

Analysis Signature accession Signature description InterPro Accession Start End
Pfam PF00498 FHA domain IPR000253 38 107
Pfam PF00069 Protein kinase domain IPR000719 152 445

SignalP

Prediction Start End Score
No records

Transmembrane domains

Domain n Start End Length
No records

InterPro

Accession Description
IPR008271 Serine/threonine-protein kinase, active site
IPR000719 Protein kinase domain
IPR000253 Forkhead-associated (FHA) domain
IPR011009 Protein kinase-like domain superfamily
IPR008984 SMAD/FHA domain superfamily
IPR017441 Protein kinase, ATP binding site

GO

Go id Term Ontology
GO:0004672 protein kinase activity MF
GO:0006468 protein phosphorylation BP
GO:0005524 ATP binding MF
GO:0005515 protein binding MF

KEGG

KEGG Orthology
K06641
K08286
K08794
K12776

EggNOG

COG category Description
T Protein tyrosine kinase

CAZy

Class Family Subfamily
No records

Transcription factor

Group
No records

Conservation of CopciAB_357261 across fungi.

Arrow shows the origin of gene family containing CopciAB_357261.

Protein

Sequence id CopciAB_357261.T0
Sequence >CopciAB_357261.T0
MATASEFRPSQRKDICAKLVTTRNGRKEVINLGFNCPVVIGRHPELCTYVISDSIISGVHCKLYAVPSPSGGIIV
SCQDLSRNGVVLNSYRIRKASVILMDGDVLVLPNMLAFTCVHIIKGPAEKLSLFDPTPPSHARTLAQKSIGNYVV
MSQCLGTGSFATVHLAFDPTHHKQVACKSIRTRRENEVRQVLKEVRILMTLKHPNINEIYDTEEDNGFIHIFLQL
CTGGDLFTYISTVNLKADRPGLCEAESKYIMFQLLTGLAYLHKKHISHRDLKPENILLHAPGPYPRILIADFGLA
RPNAYQETLNVCGTVSYLPPEGILALDNKHLGYIGMPADCWSAGVILYIMLCGSHPFDNDATYQSSWADDADSYT
SVPTESQQCLGSFSEHRQARLKARIVEEEVVFLHCPWSNLPQAKALVQNLLVHDYRRRANVFEALDSEWMVSEIS
DLQLLYRRKILGNK
Length 464

Coding

Sequence id CopciAB_357261.T0
Sequence >CopciAB_357261.T0
ATGGCCACCGCCTCTGAATTCCGACCCTCGCAGAGAAAAGATATATGCGCAAAGTTGGTGACGACGCGCAATGGG
CGTAAGGAAGTGATCAATTTGGGTTTTAATTGCCCAGTGGTCATTGGACGGCACCCTGAGCTGTGCACCTACGTG
ATCAGCGATAGCATTATCTCTGGTGTTCACTGCAAGCTATATGCAGTACCGTCGCCTTCTGGAGGGATCATTGTT
TCTTGTCAAGACTTGTCACGCAATGGAGTCGTTTTGAACAGCTATCGGATACGCAAGGCTTCTGTTATTCTTATG
GACGGAGACGTCCTTGTACTACCGAATATGCTGGCATTCACTTGCGTTCATATCATAAAGGGACCTGCGGAGAAG
CTGTCTCTATTCGATCCAACACCTCCAAGCCACGCTAGGACGCTTGCGCAGAAGAGCATCGGGAACTATGTCGTC
ATGTCGCAGTGCCTCGGAACGGGGTCCTTCGCCACCGTCCACCTGGCCTTCGATCCTACTCACCACAAGCAAGTA
GCTTGCAAAAGCATTCGAACTCGCCGCGAGAATGAAGTTCGTCAAGTTTTGAAGGAAGTAAGGATTCTCATGACA
TTGAAACATCCTAACATAAACGAGATATACGACACCGAGGAGGACAACGGATTCATTCACATCTTTCTGCAACTT
TGTACAGGCGGAGATTTGTTCACCTACATCTCTACCGTGAACCTCAAAGCCGACAGGCCAGGTTTATGCGAAGCA
GAGTCCAAGTATATAATGTTTCAACTCTTGACTGGGCTGGCATACCTTCATAAGAAACATATTTCCCATCGAGAC
TTGAAACCTGAAAACATACTACTGCACGCACCGGGCCCATATCCACGGATACTAATCGCCGACTTTGGTCTCGCT
CGGCCCAATGCATATCAAGAGACGCTGAACGTATGTGGGACAGTATCGTACTTGCCTCCAGAAGGTATACTAGCA
TTAGACAACAAGCACCTGGGATACATTGGAATGCCCGCAGACTGCTGGAGCGCTGGCGTAATCCTGTACATCATG
CTGTGCGGAAGCCATCCGTTCGACAATGACGCTACCTACCAGTCATCTTGGGCGGACGATGCGGATTCGTATACA
AGTGTGCCGACAGAATCACAGCAATGTCTGGGATCGTTCAGTGAGCACAGACAGGCAAGACTGAAAGCGAGAATC
GTGGAAGAGGAGGTCGTCTTCTTACATTGCCCCTGGAGCAACTTACCACAAGCCAAGGCATTGGTGCAGAACTTG
CTCGTCCATGATTATCGCCGGAGAGCCAACGTCTTCGAGGCACTGGACAGCGAGTGGATGGTATCGGAGATCAGC
GACCTTCAGCTACTTTACCGGCGCAAGATCTTGGGCAACAAATGA
Length 1395

Transcript

Sequence id CopciAB_357261.T0
Sequence >CopciAB_357261.T0
GTCTTTCGCTCTTGACCAGGACAATGGCCACCGCCTCTGAATTCCGACCCTCGCAGAGAAAAGATATATGCGCAA
AGTTGGTGACGACGCGCAATGGGCGTAAGGAAGTGATCAATTTGGGTTTTAATTGCCCAGTGGTCATTGGACGGC
ACCCTGAGCTGTGCACCTACGTGATCAGCGATAGCATTATCTCTGGTGTTCACTGCAAGCTATATGCAGTACCGT
CGCCTTCTGGAGGGATCATTGTTTCTTGTCAAGACTTGTCACGCAATGGAGTCGTTTTGAACAGCTATCGGATAC
GCAAGGCTTCTGTTATTCTTATGGACGGAGACGTCCTTGTACTACCGAATATGCTGGCATTCACTTGCGTTCATA
TCATAAAGGGACCTGCGGAGAAGCTGTCTCTATTCGATCCAACACCTCCAAGCCACGCTAGGACGCTTGCGCAGA
AGAGCATCGGGAACTATGTCGTCATGTCGCAGTGCCTCGGAACGGGGTCCTTCGCCACCGTCCACCTGGCCTTCG
ATCCTACTCACCACAAGCAAGTAGCTTGCAAAAGCATTCGAACTCGCCGCGAGAATGAAGTTCGTCAAGTTTTGA
AGGAAGTAAGGATTCTCATGACATTGAAACATCCTAACATAAACGAGATATACGACACCGAGGAGGACAACGGAT
TCATTCACATCTTTCTGCAACTTTGTACAGGCGGAGATTTGTTCACCTACATCTCTACCGTGAACCTCAAAGCCG
ACAGGCCAGGTTTATGCGAAGCAGAGTCCAAGTATATAATGTTTCAACTCTTGACTGGGCTGGCATACCTTCATA
AGAAACATATTTCCCATCGAGACTTGAAACCTGAAAACATACTACTGCACGCACCGGGCCCATATCCACGGATAC
TAATCGCCGACTTTGGTCTCGCTCGGCCCAATGCATATCAAGAGACGCTGAACGTATGTGGGACAGTATCGTACT
TGCCTCCAGAAGGTATACTAGCATTAGACAACAAGCACCTGGGATACATTGGAATGCCCGCAGACTGCTGGAGCG
CTGGCGTAATCCTGTACATCATGCTGTGCGGAAGCCATCCGTTCGACAATGACGCTACCTACCAGTCATCTTGGG
CGGACGATGCGGATTCGTATACAAGTGTGCCGACAGAATCACAGCAATGTCTGGGATCGTTCAGTGAGCACAGAC
AGGCAAGACTGAAAGCGAGAATCGTGGAAGAGGAGGTCGTCTTCTTACATTGCCCCTGGAGCAACTTACCACAAG
CCAAGGCATTGGTGCAGAACTTGCTCGTCCATGATTATCGCCGGAGAGCCAACGTCTTCGAGGCACTGGACAGCG
AGTGGATGGTATCGGAGATCAGCGACCTTCAGCTACTTTACCGGCGCAAGATCTTGGGCAACAAATGATTGCTTG
GAAGGGTCTCTTCAAAAATATAATTATATCGTCACGTATGGAATGTCCTTCTTGATGTGTTACAAATTCATTGGT
CTTCATTGTCACGGCCTCA
Length 1519

Gene

Sequence id CopciAB_357261.T0
Sequence >CopciAB_357261.T0
GTCTTTCGCTCTTGACCAGGACAATGGCCACCGCCTCTGAATTCCGACCCTCGCAGAGAAAAGATATATGCGCAA
AGTTGGTGACGACGCGCAATGGGCGTAAGGAAGGCAAGTGGGATTTGAGCCATCCGAGCGACAGCCATTGTTAAA
CGCAGCTGTGTAGTGATCAATTTGGGTTTTAATTGCCCAGTGGTCATTGGACGGCACCCTGAGCTGTGGTAAAAC
TTATTCTCAGACATATATGCGCATATCTGAGCTCCCTTTTCCTAGCACCTACGTGATCAGCGATAGCATTATCTC
TGGTGTTCACTGCAAGCTATATGCGTCAGTTTCCGAGAACGACAGTGACCCGGAACTGACTGAAGTCGCAGAGTA
CCGTCGCCTTCTGGAGGGATCATTGTTTCTTGTCAAGTGAGTTCTATACATTGTCCTTGAAGACATTCTGTTTAC
TCGTTTCAGGACTTGTCACGCAATGGAGTCGTTTTGAACAGCTATCGGATACGCAAGGCTTCTGTTATTCTTATG
GACGGAGACGTCCTTGTACTACCGAATATGCTGGGTCTCAGCTATTCCCTTGCTCTTTCTGGCATCGGTCTAACT
TTGTGCAGCATTCACTTGCGTTCATATCATAAAGGGACCTGCGGAGAAGCTGTCTCTATTCGATCCAACACCTCC
AAGCCACGCTAGGACGCTTGCGCAGAAGGTCTTTCATCTGTTCCCGAAAGACCTGTGTTGACCCTCTTCAATATT
CTGTTGGCTGACTATGGAGCTCTAGAGCATCGGGAACTATGTCGTCATGTCGCAGTGCCTCGGAACGGGGTCCTT
CGCCACCGTCCACCTGGCCTTCGATCCTACTCACCACAAGCAAGTAGCTTGCAAAAGCATTCGAACTCGCCGCGA
GAATGAAGTTCGTCAAGTTTTGAAGGAAGTAAGGATTCTCATGACATTGAAACATGTAAGACTCCATTCCTATTA
CTCCGTGTATCTTGTTTTTCATGACGGCCTCTTAGCCTAACATAAACGAGATATACGACACCGAGGAGGACAACG
GATTCATGTATGTTTTCGTCTCCCCTCCAGAACTCTGGAATACTCACCCAATTCGTAGTCACATCTTTCTGCAAC
TTTGTACAGGCGGAGATTTGTTCACCTACATCTCTACCGTGAACCTCAAAGCCGACAGGCCAGGTTTATGCGAAG
CAGAGTCCAAGTATATAATGTTTCAACTCTTGACTGGGCTGGCATACCTTCATAAGAAACATATTTCCCATCGAG
GTATGCGTGTCCTTCTCACCAGTGTTCGAGGTTGCTCATTTGCCGACTGTGTAGACTTGAAAGTGTGTTACCATC
TCCACGTATGAAGCTTGGTTTACAGAATGTTGTTCCAGCCTGAAAACATACTACTGCACGCACCGGGCCCATATC
CACGGATACTAATCGCCGACTTTGGTCTCGCTCGGCCCAATGCATATCAAGAGACGCTGAACGTATGTGGGACAG
TATCGTACTTGCCTCCAGAAGGTATACTAGCATTAGACAACAAGCACCTGGGATACATTGGGTATGGTCTCTTCC
CATTCCAACCCACTGATTCAGACACTTGGTATTCACTGCAACCAGAATGCCCGCAGACTGCTGGAGCGCTGGCGT
AATCCTGTACATCATGCTGTGGTAAGCAATGTCCTACATTACTCGCGAAGAAATGTTATGGTTGACTGTCTGGAC
TATAGCGGAAGCCATCCGTTCGACAATGACGCTACCTACCAGTCATCTTGGGCGGACGATGCGGATTCGTATACA
AGTGTGCCGACAGAATCACAGCAATGTCTGGGATCGTTCAGTGAGCACAGACAGGCAAGACTGAAAGCGAGAATC
GTGGAAGAGGAGGTCGTCTTCTTACATTGCCCCTGGAGCAACTTACCACAAGGTGGGTTTGAGTGTTCGGGTCAT
TCAATGAACTGACACCGTCGTTTCAGCCAAGGCATTGGTGCAGAACTTGCTCGTCCATGATTATCGCCGGAGAGC
CAACGTCTTCGAGGCACTGGACAGCGAGTGGATGGTATCGGAGATCAGCGACCTTCAGCTACTTTACCGGCGCAA
GATCTTGGGCAACAAATGATTGCTTGGAAGGGTCTCTTCAAAAATATAATTATATCGTCACGTATGGAATGTCCT
TCTTGATGTGTTACAAATTCATTGGTCTTCATTGTCACGGCCTCA
Length 2220